The relationship between knee loading during gait and cartilage thickness in nontraumatic and posttraumatic knee osteoarthritis [0.03%]
步态过程中膝关节负荷与非外伤性和外伤后膝骨关节炎软骨厚度的关系
Anthony Teoli,Melissa Cloutier-Gendron,Shirley Y K Ho et al.
Anthony Teoli et al.
The relationship between knee moments and markers of knee osteoarthritis progression has not been examined in different knee osteoarthritis subtypes. The objective was to examine relationships between external knee moments during gait and t...
Maturation- and degeneration-dependent articular cartilage metabolism via optical redox ratio imaging [0.03%]
通过光学还原比率成像依赖成熟及退化进行关节软骨代谢研究
Shannon K Walsh,Rikin Soni,Lisa M Arendt et al.
Shannon K Walsh et al.
From the two metabolic processes in healthy cartilage, glycolysis has been associated with proliferation and oxidative phosphorylation (oxphos) with matrix synthesis. Recently, metabolic dysregulation was significantly correlated with carti...
Mechanical properties and microstructural organization of common ulnar collateral ligament grafts: Palmaris longus and gracilis tendons [0.03%]
常用尺侧副韧带移植物的机械性能和显微组织结构:掌长肌腱和股薄肌腱
Lorenzo F Solon,Ryan M Castile,Matthew V Smith et al.
Lorenzo F Solon et al.
Ulnar collateral ligament (UCL) injuries are becoming increasingly common. The palmaris longus (PL) and gracilis (GR) tendons are the most common grafts used in UCL reconstructions. While clinical studies have demonstrated relatively simila...
The effect of mechanical stress on enthesis homeostasis in a rat Achilles enthesis organ culture model [0.03%]
机械应力对大鼠跟腱纤维连接组织器官培养模型中纤维连接组织稳态的影响
Taichi Saito,Ryo Nakamichi,Aki Yoshida et al.
Taichi Saito et al.
Tendons and ligaments are jointed to bones via an enthesis that is essential to the proper function of the muscular and skeletal structures. The aim of the study is to investigate the effect of mechanical stress on the enthesis. We used ex ...
Analgesic effects and arthritic changes following tramadol administration in a rat hip osteoarthritis model [0.03%]
曲马多对大鼠髋骨关节炎模型疼痛反应和关节炎变化的影响研究
Keijiro Kanno,Miyako Suzuki-Narita,Yuya Kawarai et al.
Keijiro Kanno et al.
We investigated the analgesic effects of tramadol and the arthritic changes following tramadol administration in the rat hip osteoarthritis (OA) model using mono-iodoacetate (MIA). The right hip joints of male Sprague-Dawley rats (n = 5 rat...
Age-related cellular and microstructural changes in the rotator cuff enthesis [0.03%]
肩袖肌腱附着区的年龄相关性细胞和微观结构变化
Zeling Long,Koichi Nakagawa,Zhanwen Wang et al.
Zeling Long et al.
Rotator cuff injuries increase with age. The enthesis is the most frequent site of rotator cuff injury and degeneration. Understanding age-related changes of the enthesis are essential to determine the mechanism of rotator cuff injuries, de...
TGF-beta pathway inhibition as the therapeutic acceleration of diabetic bone regeneration [0.03%]
TGF-β通路抑制作为加速糖尿病骨再生的治疗方法
Mustafa Becerikli,Felix Reinkemeier,Mehran Dadras et al.
Mustafa Becerikli et al.
Bone regeneration and fracture healing are impaired in diabetic patients due to defective functions of associated cells. Thus, the search for molecular causes and new treatment strategies are of particular clinical relevance. We investigate...
Sex-specific biomechanics and morphology of the anterior cruciate ligament during skeletal growth in a porcine model [0.03%]
骨骼生长过程中前交叉韧带的性别特异性生物力学和形态的猪模型研究
Danielle Howe,Stephanie G Cone,Jorge A Piedrahita et al.
Danielle Howe et al.
Pediatric anterior cruciate ligament (ACL) injuries are on the rise, and females experience higher ACL injury risk than males during adolescence. Studies in skeletally immature patients indicate differences in ACL size and joint laxity betw...
Inflammatory cytokines associated with outcomes in orthopedic trauma patients independent of New Injury Severity score: A pilot prospective cohort study [0.03%]
新损伤严重程度评分独立的炎症细胞因子与骨科创伤患者的临床结果相关性:一项初步前瞻性队列研究
Arun Aneja,David C Landy,Peter N Mittwede et al.
Arun Aneja et al.
Traumatic injury is the leading cause of mortality in patients under 50. It is associated with a complex inflammatory response involving hormonal, immunologic, and metabolic mediators. The marked elevation of cytokines and inflammatory medi...
Age- and sex-specific differences in ACL and ACL bundle size during adolescent growth [0.03%]
青春期生长过程中前交叉韧带及其束大小的年龄和性别差异
Stephanie G Cone,Ryan H Barnes,Danielle Howe et al.
Stephanie G Cone et al.
Anterior cruciate ligament (ACL) injuries are increasingly common in adolescents, and injuries in this age-group are associated with many unique challenges. Recent large animal studies suggest that the size and function of the major bundles...