Correction: Competition and cooperation: The plasticity of bacterial interactions across environments [0.03%]
Correction: 竞争与合作:细菌跨环境相互作用的可塑性
Josephine Solowiej-Wedderburn,Jennifer T Pentz,Ludvig Lizana et al.
Josephine Solowiej-Wedderburn et al.
[This corrects the article DOI: 10.1371/journal.pcbi.1013213.]. Copyright: © 2026 Solowiej-Wedderburn et al. This is an open access article distributed ...
Published Erratum
PLoS computational biology. 2026 Jan 15;22(1):e1013809. DOI:10.1371/journal.pcbi.1013809 2026
Cross-linking mass spectrometry for structure analysis of the intrinsically disordered Tau and phosphorylated Tau protein [0.03%]
用于分析固有无序Tau蛋白和磷酸化Tau蛋白结构的交联质谱技术
Cristian Arsene,Alexander Gates,Anne-Katrin Römmert et al.
Cristian Arsene et al.
We present a novel method for analyzing the folding of intrinsically disordered proteins (IDPs), such as Tau and phosphorylated Tau (pTau), in solution. Using cross-linking mass spectrometry (XL-MS) combined with a new downstream analysis f...
Asmita Roy,Xianyang Zhang
Asmita Roy
In genome-wide epigenetic studies, determining how exposures (e.g., Single Nucleotide Polymorphisms) affect outcomes (e.g., gene expression) through intermediate variables, such as DNA methylation, is a key challenge. Mediation analysis pro...
Peak strain dispersion as a nonlinear mediator in HFpEF: Unraveling subtype-specific pathways via SHAP-augmented ensemble modeling [0.03%]
峰值应变分散在HFpEF中的非线性介导作用:通过SHAP增强的集成建模揭示亚型特异性途径
Mingming Lin,Kai Li,Xiaofan Wang et al.
Mingming Lin et al.
Background: Heart failure with preserved ejection fraction (HFpEF) represents a heterogeneous syndrome with diverse pathophysiological mechanisms and limited therapeutic options. Peak strain dispersion (PSD) has emerged a...
Novel artificial selection method improves function of simulated microbial communities [0.03%]
一种新型的人工选择方法可提高模拟微生物群落的功能
Björn Vessman,Pablo Guridi-Fernández,Flor Inés Arias-Sánchez et al.
Björn Vessman et al.
There is increasing interest in artificially selecting or breeding microbial communities, but experiments have reported modest success. Here, we develop computational models to simulate two previously known selection methods and compare the...
Exosome-mediated chemotaxis optimizes leader-follower cell migration [0.03%]
exosome介导的化学趋向性优化领导-跟随细胞迁移
Louis González,Andrew Mugler
Louis González
Cells frequently employ extracellular vesicles, or exosomes, to signal across long distances and coordinate collective actions. Exosomes diffuse slowly, can be actively degraded, and contain stochastic amounts of molecular cargo. These feat...
Network models for bridging denoising and identifying spatial domains of spatially resolved transcriptomics [0.03%]
网络模型在空间转录组学去噪和识别空间域中的应用
Haiyue Wang,Wensheng Zhang,Zaiyi Liu et al.
Haiyue Wang et al.
Spatially resolved transcriptomics (SRT) enables the simultaneous capture of gene expression profiles and spatial localization, providing valuable insights into tissue architecture. However, the preservation of spatial information requires ...
Overcoming the widespread flaws in the annotation of vertebrate selenoprotein genes in public databases [0.03%]
克服公共数据库中脊椎动物硒蛋白基因注释的普遍缺陷
Max Ticó,Emerson Sullivan,Roderic Guigó et al.
Max Ticó et al.
Genome annotations provide the essential framework for genomic analyses, capturing our current knowledge of gene structure and function as inferred from computational predictions and experimental evidence. Even as automated annotation pipel...
The role of the spleen in red blood cell loss caused by malaria: A mathematical model [0.03%]
疟疾病因的红血细胞损失脾脏的作用-一个数学模型
Robert Moss,Saber Dini,Steven Kho et al.
Robert Moss et al.
The human spleen significantly influences red blood cell (RBC) dynamics due to its ability to retain and/or remove RBCs from peripheral blood circulation. This filtering can mediate a range of malaria disease manifestations, depending on th...
Complex relationship among vessel diameter, shear stress and blood pressure controlling vessel pruning during angiogenesis [0.03%]
血管直径、剪切应力与血压控制血管修剪之间的复杂关系在血管生成过程中
Vivek Kumar,Yosuke Hasegawa,Prashant Kumar et al.
Vivek Kumar et al.
Blood vessel pruning during angiogenesis is the optimization process of the branching pattern to improve the transport properties of a vascular network. Recent studies show that part of endothelial cells (ECs) subjected to lower shear stres...