A prospective exposome-based gene-environment interaction study on the effects of prenatal environmental exposure on fetal growth in the Shanghai Birth Cohort [0.03%]
基于上海出生队列孕期环境暴露对胎儿生长的表型组学-基因交互作用效应研究
Wen Jiang,Yun Huang,Hong Jin et al.
Wen Jiang et al.
Background: Both environmental exposure and type 2 diabetes (T2D) genetic susceptibility affect fetal growth. However, most previous studies used single exposure rather than an exposome strategy to explore the association...
Preterm and early-term delivery after heat waves in eight US states: A case-crossover study using the High-resolution Urban Meteorology for Impacts Dataset (HUMID) [0.03%]
美国8州高温天气与早产和足月早期分娩关系的病例交叉研究：利用城市高分辨率气象影响数据集（HUMID）
Amy Fitch,Mengjiao Huang,Matthew Strickland et al.
Amy Fitch et al.
Background: Heat wave frequency and intensity is increasing and this trend is more pronounced in urban areas. Heat waves may be acutely associated with early birth. ...
DeTox: an In-Silico Alternative to Animal Testing for Predicting Developmental Toxicity Potential [0.03%]
DeTox：一种用于预测发育毒性的体内模拟替代方法
Ricardo Scheufen Tieghi,Marielle Rath,José Teófilo Moreira-Filho et al.
Ricardo Scheufen Tieghi et al.
Background: Medication use among pregnant women is common, yet the safety of these medications for the developing fetus/baby is widely understudied. Quantitative Structure-Activity Relationship (QSAR) models can be used t...
Exposure to Sucralose and Its Effects on Testicular Damage and Male Infertility: Insights into Oxidative Stress and Autophagy [0.03%]
糖菊酯的暴露及其对睾丸损伤和男性不育的影响：氧化应激与自噬的新见解
Yi-Fen Chiang,Yang-Ching Chen,Ko-Chieh Huang et al.
Yi-Fen Chiang et al.
Background: The impact of non-nutritive sweeteners on male reproductive health, particularly at the cellular level, remains insufficiently explored. Sucralose's high stability and resistance to degradation during wastewat...
Household fuel use and kidney disease-related mortality: the Golestan Cohort Study [0.03%]
家庭燃料使用与肾脏疾病相关死亡率——戈勒斯坦队列研究
Michele Sassano,Monireh Sadat Seyyedsalehi,Sudabeh Alatab et al.
Michele Sassano et al.
Background: A large proportion of global population use solid fuels for household purposes, and limited evidence from previous studies suggests that it might be associated with reduced renal function. ...
Evaluating the Effects of Neburon Exposure on Ovarian Folliculogenesis Using Zebrafish and Mouse Granulosa Cell Line [0.03%]
应用斑马鱼和小鼠颗粒细胞系评价Neburon暴露对卵泡发生的影响
Chen Tang,Ying Zhang,Fucong Zhang et al.
Chen Tang et al.
Background: Ovarian folliculogenesis is crucial for female reproduction. This can be disrupted by various factors, including pollutants with aryl hydrocarbon receptor (AHR) agonistic activity, but the underlying mechanism...
Development of the Food Systems-related Greenhouse Gas Emissions Factor Database using the Korea National Health and Nutrition Examination Survey (2016-2018) [0.03%]
基于2016-2018韩国国民健康与营养调查的食品系统相关温室气体排放因子数据库开发
Jee Yeon Hong,Mi Kyung Kim
Jee Yeon Hong
Background: The increase in the frequency and scale of climate-related disasters is closely linked to greenhouse gas emissions (GHGEs) from food systems. Due to a lack of a comprehensive emission database that covers enti...
Integrating Transcriptomic and Targeted New Approach Methodologies into a Tiered Framework for Chemical Bioactivity Screening [0.03%]
整合转录组学和靶向新方法体系进行化学活性筛选分级框架的研究
Jesse D Rogers,Joseph L Bundy,Joshua A Harrill et al.
Jesse D Rogers et al.
Background: With thousands of chemicals in commerce and the environment, rapid identification of potential hazards is a critical need. Combining broad molecular profiling with targeted in vitro assays, such as high-throug...
Projections of heat-related mortality in Chinese cities: The roles of climate change, urbanization, socioeconomic adaptation, and landscape level strategies [0.03%]
气候变化、城市化和经济社会适应对我国主要城市热相关死亡率的影响及缓解措施评估研究
Xue Liu,Ming Hao,Yuyu Zhou et al.
Xue Liu et al.
Background: Physiological heat strain induced by extreme temperature in cities has led to significant heat-related deaths. Although socioeconomic adaptation is suggested to mitigate this issue, its effectiveness is limite...
Effects of Bisphenol A and Retinoic Acid Exposure on Neuron and Brain Formation: a Study in Human Induced Pluripotent Stem Cells and Zebrafish Embryos [0.03%]
双酚A和视黄酸暴露对神经元及脑发育影响的研究：人诱导多能干细胞和斑马鱼胚胎模型中的研究
Tomomi Nishie,Tomoki Taya,Shunichi Omori et al.
Tomomi Nishie et al.
Background: Developing human fetuses may be exposed to the chemical compound bisphenol A (BPA), and retinoic acid (RA) has been detected at low levels in water sources. RA signaling regulates key developmental genes and i...