Beyond the Surface: Mapping DDE's Metabolic Footprint on Adolescent Obesity [0.03%]
表面之下：绘制DDE在青少年肥胖代谢影响的地图
Zhenjiang Li,Shudi Pan,Brittney O Baumert et al.
Zhenjiang Li et al.
Background: Bariatric surgery is an intervention for severe obesity, leading to significant weight loss and metabolic improvements. However, the release of lipophilic chemicals accumulated in adipose tissue during weight ...
Time-varying exposure to element mixtures and children's cognition at 5 years of age: findings from the New Hampshire Birth Cohort Study [0.03%]
出生队列研究中儿童早期暴露于元素混合物与5岁时认知的关系
Leyre Notario Barandiaran,Julie A Bauer,Hannah E Laue et al.
Leyre Notario Barandiaran et al.
Background: Exposure to metals and metalloids (hereafter referred to as 'metals') during gestation and early childhood may affect children's neurodevelopment. However, few studies have simultaneously evaluated the impact ...
Effects of extreme heat exposure on heatstroke and liver injury in mice: The role of PPARα [0.03%]
极端高温暴露诱发小鼠热射病和肝损伤的机制及其PPARα的作用研究
Guoqing Zhang,Lisha Zhao,Jiahui Wang et al.
Guoqing Zhang et al.
Background: Liver injury is a frequent complication of heatstroke and constitutes a direct cause of death. However, only a few studies examined the mechanism underlying heatstroke-induced liver injury. ...
Multi-behavioral phenotyping in early-life-stage zebrafish for identifying disruptors of non-associative learning [0.03%]
用于识别非联想学习干扰物的早期生命阶段斑马鱼多行为表型检测
David Leuthold,Nadia K Herold,Jana Nerlich et al.
David Leuthold et al.
Background: The vertebrate nervous system is vulnerable to chemical toxicity and the widespread release of chemicals into the environment outstrips the capacity to assess their safety. The zebrafish (Danio rerio) is a pow...
Thirdhand Smoke Exposes Children Living with Smokers and Nonsmokers to Tobacco Smoke Toxicants: Racial, Income, and Housing Disparities in Hand Nicotine and Saliva Cotinine Levels [0.03%]
第三手烟暴露与吸烟者和不吸烟者的儿童接触烟草有毒物质：尼古丁及唾液中cotinine水平的种族、收入及住房差异
E Melinda Mahabee-Gittens,Ashley L Merianos,Nicolas Lopez-Galvez et al.
E Melinda Mahabee-Gittens et al.
Background: Children may be involuntarily exposed to chemical residue from thirdhand tobacco smoke (THS) in environments where tobacco has previously been used. Factors contributing to this exposure among children of nons...
An integrated machine learning framework to understand zoonotic spillover emergence across anthropogenically modified landscapes [0.03%]
一个集成的机器学习框架，用于理解人工改造景观中人畜共患病溢出的出现
Yinsheng Zhang,Jinchen Wang,Luqi Wang et al.
Yinsheng Zhang et al.
Background: Anthropogenic land modification influences human-livestock-wildlife interactions and zoonotic spillover emergence. However, the extent of this impact remains unclear and could be better understood through the ...
Effect of household air pollution on the gut microbiome and virome of adult women living in Uganda [0.03%]
乌干达成人女性家庭空气污染对肠道微生物群和病毒群的影响
Ching-Ying Huang,Edwin Nuwagira,Michael Tisza et al.
Ching-Ying Huang et al.
Background: Emerging observational studies suggest air pollution can influence the gut microbiome. However, this association is often highly confounded by factors such as diet and poverty. The gut virome may influence res...
Comparison of Temperature-Mortality Associations Across the Middle East Using Different Exposure Estimation Approaches [0.03%]
不同暴露估算方法下的中东地区气温-死亡关系的比较研究
Yazan Alwadi,Barrak Alahmad,Marc G Weisskopf et al.
Yazan Alwadi et al.
Background: Traditional temperature-health studies have predominantly relied on temperature measurements from stations or modelled spatial averages from gridded temperature datasets. It has been suggested that population-...
External Validation of STopTox - Novel Alternative Method (NAM) for Acute Systemic and Topical Toxicity [0.03%]
STopTox-NAM急性系统毒性和局部毒性替代方法的外部验证
Ricardo Scheufen Tieghi,Cleber C Melo-Filho,Holli-Joi Martin et al.
Ricardo Scheufen Tieghi et al.
Statistical methods for chemical mixtures: a roadmap for practitioners using simulation studies and a sample data analysis in the PROTECT cohort [0.03%]
化学混合物的统计方法：使用模拟研究和PROTECT队列中样本数据分析的方法指南
Wei Hao,Amber L Cathey,Max M Aung et al.
Wei Hao et al.
Background: Quantitative characterization of the health impacts associated with exposure to chemical mixtures has received considerable attention in current environmental and epidemiological studies. With many existing st...