Aging of intrinsic circadian rhythms and sleep in a diurnal nonhuman primate, Macaca mulatta [0.03%]
恒河猴的内在昼夜节律和睡眠随老化的变化
I V Zhdanova,K Masuda,C Quasarano-Kourkoulis et al.
I V Zhdanova et al.
There is growing evidence that alterations in the intrinsic circadian clock and sleep might affect the aging process. The rhesus monkey (Macaca mulatta) provides unique opportunities to explore the role of the clock in successful and unsucc...
Altered expression of circadian clock genes in human chronic myeloid leukemia [0.03%]
人慢性粒细胞白血病中昼夜钟基因表达的改变
Ming-Yu Yang,Wen-Chi Yang,Pai-Mei Lin et al.
Ming-Yu Yang et al.
Circadian clock genes use transcriptional-translational feedback loops to control circadian rhythms. Recent studies have demonstrated that expression of some circadian clock genes displays daily oscillation in peripheral tissues including p...
Elimination of short-day melatonin signaling accelerates gonadal recrudescence but does not break refractoriness in male Turkish hamsters [0.03%]
土耳其仓鼠中短日褪黑素信号的消除加速了生殖腺的再生但并未打破雄性的抗拒性
Stephan G Jarjisian,Irving Zucker
Stephan G Jarjisian
Long days stimulate and short days (SDs) inhibit the reproductive axis of photoperiodic rodents. In long-day Turkish hamsters, unlike most other rodents, elimination of pineal melatonin secretion by constant light or pinealectomy initiates ...
Lab mice in the field: unorthodox daily activity and effects of a dysfunctional circadian clock allele [0.03%]
实验室老鼠野外生活:日常活动和昼夜节律钟突变基因的功能效应
Serge Daan,Kamiel Spoelstra,Urs Albrecht et al.
Serge Daan et al.
Daily patterns of animal behavior are potentially of vast functional importance. Fitness benefits have been identified in nature by the association between individual timing and survival or by the fate of individuals after experimental dele...
Purinergic signals regulate daily S-phase cell activity in the ciliary marginal zone of the zebrafish retina [0.03%]
嘌呤能信号调节斑马鱼视网膜睫状边际区S期细胞的每日活性
Maria Jimena Ricatti,Ariadna Gabriela Battista,Maria Zorrilla Zubilete et al.
Maria Jimena Ricatti et al.
Regeneration and growth that occur in the adult teleost retina have been helpful in identifying molecular and cellular mechanisms underlying cell proliferation and differentiation. Here, it is reported that S-phase cell number, in the cilia...
Gastrin-releasing peptide modulates fast delayed rectifier potassium current in Per1-expressing SCN neurons [0.03%]
胃泌素释放肽通过PER1调节快速延迟整流型钾电流来调控视交叉上核神经元放电速率
Karen L Gamble,Takashi Kudo,Christopher S Colwell et al.
Karen L Gamble et al.
The mammalian circadian clock in the suprachiasmatic nucleus (SCN) drives and maintains 24-h physiological rhythms, the phases of which are set by the local environmental light-dark cycle. Gastrin-releasing peptide (GRP) communicates photic...
Circadian clock parameter measurement: characterization of clock transcription factors using surface plasmon resonance [0.03%]
circadian钟参数测量:利用表面等离子体共振法表征clock转录因子
John S ONeill,Gerben van Ooijen,Thierry Le Bihan et al.
John S ONeill et al.
To refine mathematical models of the transcriptional/translational feedback loop in the clockwork of Arabidopsis thaliana, the investigators sought to determine the affinity of the transcription factors LHY, CCA1, and CHE for their cognate ...
Lunar rhythms in the deep sea: evidence from the reproductive periodicity of several marine invertebrates [0.03%]
深海中的月相变化规律——来自几种海洋无脊椎动物繁殖周期的证据
Annie Mercier,Zhao Sun,Sandrine Baillon et al.
Annie Mercier et al.
While lunar rhythms are commonly documented in plants and animals living in terrestrial and shallow-water environments, deep-sea organisms have essentially been overlooked in that respect. This report describes evidence of lunar periodicity...
Brian P Grone,Doris Chang,Patrice Bourgin et al.
Brian P Grone et al.
Light can induce arrhythmia in circadian systems by several weeks of constant light or by a brief light stimulus given at the transition point of the phase response curve. In the present study, a novel light treatment consisting of phase ad...
Nico Romeijn,Eus J W Van Someren
Nico Romeijn
Skin temperature shows spontaneous ultradian fluctuations during everyday-life wakefulness. Previous work showed that mild manipulations of skin temperature affect human sleep and vigilance, presumably by influencing neuronal systems involv...