Wavelet measurement suggests cause of period instability in mammalian circadian neurons [0.03%]
小波测量表明了哺乳动物昼夜神经元周期不稳定性的原因
Kirsten Meeker,Richard Harang,Alexis B Webb et al.
Kirsten Meeker et al.
Cells in the suprachiasmatic nucleus (SCN) display remarkable precision, while either physically or chemically decoupling these cells from each other leads to a dramatic increase in period-to-period variability. Where previous studies have ...
Can photoperiod predict mortality in the 1918-1920 influenza pandemic? [0.03%]
光照周期能预测1918-1920年流感大流行的死亡率吗？
Brian J Prendergast
Brian J Prendergast
Amplitude of the seasonal change in day length increases with distance from the equator, and changes in day length markedly alter immune function in diverse nonhuman animal models of infection. Historical records of mortality data, ambient ...
Jiahui S Liu,Christopher L Passaglia
Jiahui S Liu
The lateral eyes of the horseshoe crab (Limulus polyphemus) show a daily rhythm in visual sensitivity that is mediated by efferent nerve signals from a circadian clock in the crab's brain. How these signals communicate circadian messages is...
Scheduled food hastens re-entrainment more than melatonin does after a 6-h phase advance of the light-dark cycle in rats [0.03%]
在大鼠的光暗周期提前6小时后，定时进食比褪黑素更快地促进再适应
M Ángeles-Castellanos,J M Amaya,R Salgado-Delgado et al.
M Ángeles-Castellanos et al.
Circadian desynchrony occurs when individuals are exposed to abrupt phase shifts of the light-dark cycle, as in jet lag. For reducing symptoms and for speeding up resynchronization, several strategies have been suggested, including schedule...
A "melanopic" spectral efficiency function predicts the sensitivity of melanopsin photoreceptors to polychromatic lights [0.03%]
一个“黑视性”的光谱效率函数可以预测多色光敏感的黑视蛋白感光受体的灵敏度
Jazi al Enezi,Victoria Revell,Timothy Brown et al.
Jazi al Enezi et al.
Photoreception in the mammalian retina is not restricted to rods and cones but extends to a small number of intrinsically photosensitive retinal ganglion cells expressing the photopigment melanopsin. These mRGCs are especially important con...
Interval timing is intact in arrhythmic Cry1/Cry2-deficient mice [0.03%]
缺乏Cry1/Cry2的节律紊乱的小鼠的时间间隔正常化
Efstathios B Papachristos,Edwin H Jacobs,Ype Elgersma
Efstathios B Papachristos
Localizing the self in time is fundamental for daily life functioning and is lacking in severe disabling neuropsychiatric disorders like schizophrenia. Brains keep track of time across an impressive range of scales. Great progress has been ...
Stefanie Krug,Judy McKinley Brewer,Alexandre S Bois et al.
Stefanie Krug et al.
The circadian mutation duper in Syrian hamsters shortens the free-running circadian period (τ(DD)) by 2 hours when expressed on a tau mutant (τ(ss)) background and by 1 hour on a wild-type background. We have examined the effects of this ...
Stefanie Monecke,Judy McKinley Brewer,Stefanie Krug et al.
Stefanie Monecke et al.
Three animals born to homozygous tau mutant (τ(ss), "super short") Syrian hamsters showed extremely short free-running periods of locomotor activity (τ(DD) of approximately 17.8 hours). Inbreeding produced 33 such "super duper" animals, w...
Human diurnal preference and circadian rhythmicity are not associated with the CLOCK 3111C/T gene polymorphism [0.03%]
人日常偏爱和昼夜节律不受CLOCK 3111CT基因多态性影响
Anne-Marie Chang,Alison M Buch,Dayna S Bradstreet et al.
Anne-Marie Chang et al.
Genetic association studies of the CLOCK 3111C/T polymorphism and diurnal preference have yielded conflicting results since the first report that the 3111C allele was associated with eveningness. The goal of the present study was to investi...
Resveratrol dietary supplementation shortens the free-running circadian period and decreases body temperature in a prosimian primate [0.03%]
白藜芦醇饮食补充缩短了原猴类动物的自由运转昼夜节律周期并降低了体温
Fabien Pifferi,Alexandre Dal-Pan,Michael Menaker et al.
Fabien Pifferi et al.
Resveratrol (RSV) is a dietary polyphenolic compound with several positive effects on metabolic functions and longevity. We tested the effect of RSV on the circadian clock in a nonhuman primate, the gray mouse lemur. The impact of a 2-week ...