Tanya L Leise,Mary E Harrington
Tanya L Leise
Analysis of circadian oscillations that exhibit variability in period or amplitude can be accomplished through wavelet transforms. Wavelet-based methods can also be used quite effectively to remove trend and noise from time series and to as...
Revisiting spontaneous internal desynchrony using a quantitative model of sleep physiology [0.03%]
利用睡眠生理学定量模型重新研究自发性内部脱同步现象
Andrew J K Phillips,Charles A Czeisler,Elizabeth B Klerman
Andrew J K Phillips
Early attempts to characterize free-running human circadian rhythms generated three notable results: 1) observed circadian periods of 25 hours (considerably longer than the now established 24.1- to 24.2-hour average intrinsic circadian peri...
Multisensory non-photoperiodic cue advances the onset of seasonal breeding in Island canaries (Serinus canaria) [0.03%]
多重感官非光周期线索提前岛上金丝雀(Serinus canaria)季节繁殖的开始
Cornelia Voigt,Torsten Meiners,Andries Ter Maat et al.
Cornelia Voigt et al.
In most temperate zone vertebrates, photoperiodic change plays the major role in the timing of seasonal breeding. However, direct environmental stimuli such as temperature, rainfall, or availability of food are thought to be important for f...
Disruption of circadian rhythms accelerates development of diabetes through pancreatic beta-cell loss and dysfunction [0.03%]
昼夜节律紊乱通过胰岛β细胞的丢失和功能障碍加速糖尿病的发生发展
John E Gale,Heather I Cox,Jingyi Qian et al.
John E Gale et al.
Type 2 diabetes mellitus (T2DM) is complex metabolic disease that arises as a consequence of interactions between genetic predisposition and environmental triggers. One recently described environmental trigger associated with development of...
Cardiac-specific mutation of Clock alters the quantitative measurements of physical activities without changing behavioral circadian rhythms [0.03%]
心脏特异性Clock基因突变不影响行为昼夜节律但可改变运动小鼠的运动特征
Michael L Ko,Liheng Shi,Ju-Yun Tsai et al.
Michael L Ko et al.
Even though peripheral circadian oscillators in the cardiovascular system are known to exist, the daily rhythms of the cardiovascular system are mainly attributed to autonomic or hormonal inputs under the control of the central oscillator, ...
Xi Wu,Zhiwei Liu,Guangsen Shi et al.
Xi Wu et al.
Circadian clocks are believed to provide the selective advantage of anticipation, thus allowing organisms to respond efficiently to stimuli at the appropriate moment. Disrupted circadian rhythms have been found to affect a variety of basic ...
Robert Dallmann,Jason P DeBruyne,David R Weaver
Robert Dallmann
Mice lacking the CLOCK protein have a relatively subtle circadian phenotype, including a slightly shorter period in constant darkness, differences in phase resetting after 4-hour light pulses in the early and late night, and a variably adva...
Synaptotagmin10-Cre, a driver to disrupt clock genes in the SCN [0.03%]
Synaptotagmin10-Cre,敲除视交叉上核 CLOCK 基因的工具
Jana Husse,Xunlei Zhou,Anton Shostak et al.
Jana Husse et al.
Surgical lesion of the suprachiasmatic nuclei (SCN) profoundly affects the circadian timing system. A complication of SCN ablations is the concomitant scission of SCN afferents and efferents. Genetic disruption of the molecular clockwork in...
Norman F Ruby
Norman F Ruby
A report by Buhr et al. (2010) proposed that the suprachiasmatic nucleus (SCN) is resistant to phase shifts induced by heat pulses and to entrainment by temperature cycles. These findings are inconsistent with those from studies by other la...
Site-specific changes in brain extra-SCN oscillators during early pregnancy in the rat [0.03%]
大鼠早期妊娠期间大脑非视交叉上核振荡器的部位特异性变化
Jessica A Schrader,Antonio A Nunez,Laura Smale
Jessica A Schrader
The influence of circadian timekeeping systems on behavior and physiology can change substantially as female mammals undergo the transition from a nonpregnant to a pregnant state. Here, we examined the possibility that site-specific changes...
Comparative Study
Journal of biological rhythms. 2011 Aug;26(4):363-7. DOI:10.1177/0748730411409714 2011