Aberrant development of the suprachiasmatic nucleus and circadian rhythms in mice lacking the homeodomain protein Six6 [0.03%]
Six6缺失小鼠视交叉上核及昼夜节律的异常发展
Daniel D Clark,Michael R Gorman,Megumi Hatori et al.
Daniel D Clark et al.
The suprachiasmatic nucleus (SCN) of the mammalian hypothalamus is the central pacemaker for peripheral and organismal circadian rhythms. The development of this hypothalamic structure depends on genetic programs throughout embryogenesis. W...
Pamela Menegazzi,Stefano Vanin,Taishi Yoshii et al.
Pamela Menegazzi et al.
The circadian clock modulates the adaptive daily patterns of physiology and behavior and adjusts these rhythms to seasonal changes. Recent studies of seasonal locomotor activity patterns of wild-type and clock mutant fruit flies in quasi-na...
Sleep-wake behavior in the rat: ultradian rhythms in a light-dark cycle and continuous bright light [0.03%]
大鼠光暗周期和持续强光下的睡眠-觉醒行为：亚昼夜节律
Richard Stephenson,Joonbum Lim,Svetlana Famina et al.
Richard Stephenson et al.
Ultradian rhythms are a prominent but little-studied feature of mammalian sleep-wake and rest-activity patterns. They are especially evident in long-term records of behavioral state in polyphasic animals such as rodents. However, few attemp...
Comparative Study
Journal of biological rhythms. 2012 Dec;27(6):490-501. DOI:10.1177/0748730412461247 2012
Tissue-specific interaction of Per1/2 and Dec2 in the regulation of fibroblast circadian rhythms [0.03%]
Per1/2与Dec2在纤维母细胞昼夜节律调节中的组织特异性相互作用
Anthony H Tsang,Carmen Sánchez-Moreno,Brid Bode et al.
Anthony H Tsang et al.
In mammals, the molecular circadian clockwork is comprised of interlocked transcriptional-translational feedback loops (TTLs). Three Period (Per1-3) and 2 Dec (Dec1/2) genes interact in regulating the activity of the transcriptional activat...
gb'clock is expressed in the optic lobe and is required for the circadian clock in the cricket Gryllus bimaculatus [0.03%]
周期基因在蟋蟀双斑翅聒夜蜂神经元中的表达对其昼夜节律钟是必需的
Yoshiyuki Moriyama,Yuichi Kamae,Outa Uryu et al.
Yoshiyuki Moriyama et al.
Reverse genetic studies have revealed that common clock genes, such as period (per), timeless (tim), cycle (cyc), and Clock (Clk), are involved in the circadian clock mechanism among a wide variety of insects. However, to what degree the mo...
Sequence and expression of per, tim1, and cry2 genes in the Madeira cockroach Rhyparobia maderae [0.03%]
墨氏负鼠蟑per、tim1和cry2基因的序列及其表达模式分析
Achim Werckenthin,Christian Derst,Monika Stengl
Achim Werckenthin
Most of what we know today about the molecular constituents of the insect circadian clock was discovered in the fruit fly Drosophila melanogaster. Various other holometabolous and some hemimetabolous insects have also been examined for the ...
Cry1-/- circadian rhythmicity depends on SCN intercellular coupling [0.03%]
Cry1基因敲除小鼠的视交叉上核细胞间偶联依赖性昼夜节律性
Jennifer A Evans,Haiyun Pan,Andrew C Liu et al.
Jennifer A Evans et al.
In mammals, the suprachiasmatic nucleus (SCN) is the central pacemaker organizing circadian rhythms of behavior and physiology. At the cellular level, the mammalian clock consists of autoregulatory feedback loops involving a set of "clock g...
Laboratory versus nature: the two sides of the Drosophila circadian clock [0.03%]
实验室与自然：果蝇昼夜节律钟的两面性
Pamela Menegazzi,Taishi Yoshii,Charlotte Helfrich-Förster
Pamela Menegazzi
The daily pattern of animal behavior is thought to be of potential enormous importance for survival. Here, we compared the daily activity pattern of Drosophila melanogaster wild-type flies and the clock-impaired mutants, per(01) and Clk(Jrk...
Comparative Study
Journal of biological rhythms. 2012 Dec;27(6):433-42. DOI:10.1177/0748730412463181 2012
Pigment-dispersing factor is involved in age-dependent rhythm changes in Drosophila melanogaster [0.03%]
色素分散因子参与果蝇(Drosophila melanogaster)年龄依赖性节律变化
Yujiro Umezaki,Taishi Yoshii,Tomoaki Kawaguchi et al.
Yujiro Umezaki et al.
Most animals show rest/activity rhythms that are regulated by an endogenous timing mechanism, the so-called circadian system. The rhythm becomes weaker with age, but the mechanism underlying the age-associated rhythm change remains to be el...
Individual differences in circadian waveform of Siberian hamsters under multiple lighting conditions [0.03%]
多种光照条件下叙利亚仓鼠昼夜节律波形的个体差异
Jennifer A Evans,Jeffrey A Elliott,Michael R Gorman
Jennifer A Evans
Because the circadian clock in the mammalian brain derives from a network of interacting cellular oscillators, characterizing the nature and bases of circadian coupling is fundamental to understanding how the pacemaker operates. Various phe...