An escort to the ER [0.03%]
陪护就医之旅
Grant Miura
Grant Miura
Uncaged by ROS [0.03%]
ROS释放的无笼光遗传学技术
Gene Chong
Gene Chong
Christos Adamopoulos,Kostas A Papavassiliou,Athanasios G Papavassiliou
Christos Adamopoulos
A family portrait of lanmodulin selectivity for enhanced rare-earth separations [0.03%]
用于增强稀土分离的 lanmodulin 系列衍生物家族 portraits
Patrick Diep,Cody S Madsen,Wonseok Choi et al.
Patrick Diep et al.
Proteins offer a molecular design space to create bespoke ligands for the separation of critical metals like rare earth elements (REs). However, data-intensive approaches to tune metalloprotein selectivity are constrained by the low-through...
Merve Aslan,Ennio A d&#x;Amico,Nathan H Cho et al.
Merve Aslan et al.
During cell division, the nuclear mitotic apparatus protein (NuMA) orchestrates the focusing of microtubule minus-ends in spindle poles and cortical force generation on astral microtubules by interacting with dynein motors, microtubules and...
IDO1 regulating ROS rhythm reveals glycogenolysis/PPP as a cancer treatment target [0.03%]
IDO1调节ROS节律揭示糖原分解/磷酸戊糖途径是癌症治疗靶点
Nannan Zhou,Zheng Ling,Xiankai Cao et al.
Nannan Zhou et al.
Reactive oxygen species (ROS) dynamics exhibits rhythmic oscillations in cancer cells but how this rhythm influences tumorigenesis and therapeutic responses remains unclear. Here we found coexistence of ROS rhythmicity and rhythm loss in tu...
Iterative acylation on mature lasso peptides by widespread acetyltransferases [0.03%]
成熟的环肽类天然产物的迭代酰基化反应
Jiang Xiong,Shanquan Wu,Zi-Qi Liang et al.
Jiang Xiong et al.
The biosynthesis of ribosomally synthesized and posttranslationally modified peptides (RiPPs) leverages iterative catalysis to enhance structural and biological diversity. Traditionally, iterative enzymes install posttranslational modificat...
Quansheng Du,Xin Wang,Yangming Wang et al.
Quansheng Du et al.
A druggable redox switch on SHP1 controls macrophage inflammation [0.03%]
SHP1上的一个可药物化的氧化还原开关控制巨噬细胞的炎症反应
Mei Ying Ng,Meredith N Nix,Guangyan Du et al.
Mei Ying Ng et al.
Immunological proteins are major disease targets, yet most remain undrugged. Post-translational redox modification of cysteine residues has emerged as an important mode of immune cell regulation, particularly in macrophage cytokine response...