Chrysoeriol-Mediated Neuroprotection in Parkinson's Disease in Mice: Targeting Apoptosis, α-Synuclein Accumulation, and Functional Recovery [0.03%]
染料木素介导的小鼠帕金森病神经保护作用：靶向凋亡、α-突触核蛋白聚集及功能恢复
Mehak Ali,Mehwish Mehreen,Saima Batool et al.
Mehak Ali et al.
Parkinson's disease (PD) is a neurodegenerative disorder marked by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta, leading to significant motor dysfunction. Current treatments stabilize dopamine levels bu...
Sophia Moret,Jordan A Galbraith,Giulia Lorenzon et al.
Sophia Moret et al.
Certain musical abilities can endure even as language, memory, and behavior decline in dementia, yet the neural basis of this resilience remains poorly understood. We draw on behavioral and neuroimaging evidence to explain why musicality is...
Burden of Neurological Disorders in Resource-Limited Settings: Lessons from Pakistan for Global Neurology [0.03%]
巴基斯坦的全球神经病学负担及其资源限制带来的挑战给全世界带来什么启示？
Syeda Briha Fatima,Mahnoor Mughal,Mazhar Badshah et al.
Syeda Briha Fatima et al.
Neurological disorders (NDs) are a leading global cause of disability and mortality, with their burden falling disproportionately on low- and middle-income countries (LMICs). Pakistan exemplifies the systemic challenges faced in resource-li...
Comparative Analysis of Prenatal Stress Models: Placental and Neurodevelopmental Outcomes in Mice [0.03%]
孕期压力模型的比较分析：小鼠胎盘和神经发育结局
Mia Dukle,Faith M Fairbairn,Sara V Maurer et al.
Mia Dukle et al.
Prenatal stress affects offspring development. The placenta, an important maternal-fetal mediator, is susceptible to prenatal stress, and its biology affects fetal neurodevelopment, particularly ventral forebrain. Ventral forebrain developm...
Comparative Study
The Yale journal of biology and medicine. 2026 Mar 31;99(1):127-141. DOI:10.59249/MHFP3728 2026
Computational Investigation of Flavonoid-Associated Molecular Pathways in Astrogliosis Modulation [0.03%]
黄酮类化合物与分子通路在星形胶质细胞增生调节中的计算研究
Secil Akyildiz Demir,Nergiz Gürbüz Çolak
Secil Akyildiz Demir
Astrogliosis is characterized by an abnormal increase in the number of astrocytes in the brain due to damage, trauma, infection, ischemia, stroke, autoimmune responses, or neurodegenerative disorders. Glial Fibrillary Acidic Protein (GFAP) ...
Regulation and Interaction Among SOCS1 and SOCS3 by MicroRNAs in Multiple Sclerosis: A Review and In Silico Analysis [0.03%]
微小核糖核酸对多发性硬化中SOCS1和SOCS3的调节及相互作用：综述与生物信息学分析
Moisés Manuel Gallardo-Pérez,Solón Javier Garcés-Eisele,José Manuel Madrazo-Cabo et al.
Moisés Manuel Gallardo-Pérez et al.
Multiple sclerosis (MS) is a chronic demyelinating disease and a leading cause of disability in young adults. Its pathophysiology involves complex genetic and immunological mechanisms, among which the suppressors of cytokine signaling (SOCS...
Homozygous PTRHD1 Mutation in Intellectual Disability and Atypical Parkinsonism [0.03%]
PTRHD1同合子突变致智能障碍和非典型帕金森病综合征
Esra Yıldız Bölükbaşı,Sara Mumtaz,Muhammad Afzal et al.
Esra Yıldız Bölükbaşı et al.
Five different homozygous PTRHD1 mutations, two of them in more than one family, have been reported as responsible for intellectual disability (ID) and parkinsonism. In all 10 families, onset of ID was early childhood, and in parkinsonism, ...
The Bidirectional Regulatory Role of Neuroimmune Interaction in Neurodevelopment and Neurodegenerative Diseases [0.03%]
神经免疫互作在神经发育和神经退行性疾病中的双向调控作用
Junjie Liu,Yangke Wang,Yifan Long et al.
Junjie Liu et al.
Neurological disorders pose a major public health challenge worldwide, with neuroimmune interaction emerging as a core regulatory mechanism underlying their pathogenesis. This review highlights the progression from static association to dyn...
Neurodegeneration and Homelessness: A Bidirectional Relationship Shaping Health and Vulnerability [0.03%]
神经退行性病变和无家可归：塑造健康和脆弱性的双向关系
Anna C F Stouffer,Sandhya L Kumar
Anna C F Stouffer
Neurodegeneration and homelessness are deeply interconnected. Many structural, environmental, and interpersonal conditions experienced during homelessness-for example, inconsistent healthcare, forced displacement, chronic stress, and trauma...
Gonadotropins Across the Lifespan: Their role in the Neurodevelopment-Neurodegeneration Continuum [0.03%]
促性腺激素生命周期中的作用：在神经发育-神经退行性病变连续谱系中的角色
Jordan A Galbraith,Mohamed Z Elhassan,Joshua F Rocha et al.
Jordan A Galbraith et al.
Gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH), mediate critical reproductive functions via the hypothalamus-pituitary-gonadal axis. Their levels fluctuate across the lifespan, particularly during puberty and...