Single-Nucleotide Polymorphism Genotyping of exoS in Pseudomonas aeruginosa Using Dual-Color Fluorescence Hybridization and Magnetic Separation [0.03%]
应用双色荧光杂交和磁分离技术对绿脓杆菌exoS单核苷酸多态性进行基因分型研究
Yongjun Tang,Zeeshan Ali,Jianguo Dai et al.
Yongjun Tang et al.
Pseudomonas aeruginosa exoS gene contains important replacement (non-synonymous) single-nucleotide polymorphism (SNP) loci, of which mutations in loci 162 (G162A) and 434 (G434C) in exoS greatly affects virulence. The present study aimed to...
A Portable Multi-Channel Turbidity System for Rapid Detection of Pathogens by Loop-Mediated Isothermal Amplification [0.03%]
一种用于环介导等温扩增法快速检测病原体的多通道浊度便携式系统
Zhu Chen,Tong Yang,Haowen Yang et al.
Zhu Chen et al.
This study aimed at developing a portable multi-channel turbidity system (21 cm in length, 15.5 cm in width and 11.5 cm in depth) by real-time loop-mediated isothermal amplification (LAMP) method for rapid detection of pathogens. The develo...
Ciclosporin A as a Reversal Agent Against Concurrent Multidrug Resistance in Tumors with Nanobubbles [0.03%]
环孢素A作为纳米气泡介导的肿瘤多药耐药逆转剂
Shuang Ding,Nishant Patel,Haijun Zhang
Shuang Ding
The purpose of this work was to challenge the multidrug resistance (MDR) in tumor through nanobubbles (NB) co-loaded reversal agent and chemotherapeutic drug layer by layer. The core/shell NB structure contains Doxorubicin (Dox) as anticanc...
Poly(lactic-co-glycolic acid)/Polycaprolactone Nanofibrous Membranes for High-Efficient Capture of Nano- and Microsized Particulate Matter [0.03%]
聚乳酸-co-乙交酯)/聚己内酯纳米纤维膜高效捕获纳米和微米级颗粒物研究
Wenshi Xu,Mengyu Guo,Jing Liu et al.
Wenshi Xu et al.
The incidence of many diseases is closely related to air pollution. Suspended particulate matter of different sizes represents a major source of environmental pollution. Fine particles, especially ultrafine particles smaller than 2.5 μm, m...
Nano-Vesicles are a Potential Tool to Monitor Therapeutic Efficacy of Carbon Ion Radiotherapy in Prostate Cancer [0.03%]
纳米囊泡可作为监测碳离子放疗在前列腺癌中治疗效果的潜在工具
Qi Yu,Ping Li,Meilin Weng et al.
Qi Yu et al.
Exosomes are nano-vesicles that contribute to the effectiveness of many treatments. The aim of this study was to identify profiles of microRNA (miRNA) contained in serum exosomes that are differentially regulated in patients with prostate c...
Novel Application of Cell Penetrating R11 Peptide for Diagnosis of Bladder Cancer [0.03%]
用于膀胱癌诊断的细胞穿膜肽R11的新应用
Yiqing Du,Lei Wang,Weiyi Wang et al.
Yiqing Du et al.
Objective: As a novel cell-permeable peptide, polyarginine (R11) showed great potential as contrast agent to target bladder cancer (BCa) for therapeutic applications. However, its diagnostic ability and uptake efficiency ...
One-Step Synthesis of DNA Templated Water-Soluble Au-Ag Bimetallic Nanoclusters for Ratiometric Fluorescence Detection of DNA [0.03%]
一步合成DNA模板水溶性金-银双金属纳米团簇用于DNA比率型荧光检测
Taotao Li,Huan Yi,Yuan Liu et al.
Taotao Li et al.
DNA strands have been used as templates to form different sized silver nanoclusters. Although DNA templated silver nanoclusters (NCs) probes which show outstanding fluorescence properties have been widely applied in chemical sensing and cel...
Enhanced In Vitro and In Vivo Anticancer Properties by Using a Nanocarrier for Co-Delivery of Antitumor Polypeptide and Curcumin [0.03%]
用于联合递送抗肿瘤多肽和姜黄素的纳米载体增强其体内外抗癌性能
Mengjiao Qi,Shaohua Zou,Chunjing Guo et al.
Mengjiao Qi et al.
In this paper, a novel pH and redox dual-sensitive nanocarrier loaded with curcumin (Cur) and anticancer polypeptide (AP) was developed for dual targeting mitochondrial and CD44 receptor. The amphiphilic block copolymer was prepared by trip...
Exchangeability of FITC-SiO₂ Nanoparticles Between Cancer Cells Increases the Range of Drug Delivery [0.03%]
FITC-SiO₂纳米颗粒在癌细胞间的交换性可增加药物传输的范围
Guoying Deng,Zizheng Wu,Feng Zhou et al.
Guoying Deng et al.
Drug delivery system studies aim to improve nanoparticle (NP) formulation to enable efficient delivery of NPs to tumors. However, NPs must be transported by blood or through direct injection. How NPs leave the circulatory system and how NPs...
Glycyrrhetinic Acid-Modified Norcantharidin Nanoparticles for Active Targeted Therapy of Hepatocellular Carcinoma [0.03%]
甘草酸改性昆明苏打纳米粒的活性靶向治疗肝癌作用研究
Heng Zhang,Yu Jiang,XiaoLing Ni et al.
Heng Zhang et al.
Norcantharidin (NCTD), the demethylated analogue of cantharidin, has been confirmed to have a good anti-tumor effect against hepatocellular carcinoma (HCC). However, its use is limited by its poor water solubility and low tumortargeting eff...