Accelerated Neutral Atom Beam (ANAB) Modified Poly-Ether-Ether-Ketone for Increasing In Vitro Bone Cell Functions and Reducing Bacteria Colonization Without Drugs or Antibiotics [0.03%]
无需药物或抗生素即可增加体外骨细胞功能并减少细菌定植的加速中性原子束改性的聚醚醚酮
Thomas J Webster,Jeffrey R Shallenberger,Elazer R Edelman et al.
Thomas J Webster et al.
Poly-ether-ether-ketone (PEEK) has become the spinal implant material of choice due to its radiolucency, low elastic modulus, manufacturability, and mechanical durability. However, studies have highlighted less that optimal cytocompatibilit...
Effect of Hydroaloholic Extract of Rotula Aquatica Lour on Gentamicin-Induced Nephrotoxicity in Wistar Albino Rats: An In Vitro and In Vivo Approach [0.03%]
罗氏风铃草水提物对醋酸 gentamicin 致肾毒性的体内及体外研究 эффект гидроалкогольного экстракта Rotula aquatica Lour на нефотоксичность, вызванную гентамицином у крыс Wistar
Siju Ellickal Narayanan,Mohamed A Abdelgawad,Yusuf S Althobaiti et al.
Siju Ellickal Narayanan et al.
One-third of the world population suffer from kidney complications such as acute and chronic renal failure, renal calculi, kidney stones, Fanconi's syndrome and urethritis which doesn't have a proper effective treatment regimen. The current...
Photothermolysis Mediated by Gold Nanorods Conjugated with Epidermal Growth Factor Receptor (EGFR) Monoclonal Antibody Induces Apoptosis via the Mitochondrial Apoptosis Pathway in Laryngeal Squamous Cell Cancer [0.03%]
表面连接表皮生长因子受体单克隆抗体的金纳米棒介导光热疗通过线粒体凋亡途径诱导喉鳞状细胞癌细胞凋亡
Shi-Wen Zhang,Hao Wang,You-Yu Qiu et al.
Shi-Wen Zhang et al.
Gold nanorods (AuNRs) have unique optical properties and biological affinity and can be used to treat tumors when conjugated with other protein molecules. Our previous studies have shown that EGFR monoclonal antibody (EGFRmAb)-modified AuNR...
Treg Cell Evaluation in Patients with Acquired Immune Deficiency Syndrome with Poor Immune Reconstitution and Human Immunodeficiency Virus-Infected Treg Cell Prevention by Polymeric Nanoparticle Drug Delivery System [0.03%]
艾滋病免疫重建不良患者的调节性T细胞评价及人类免疫缺陷病毒感染调节性T细胞的纳米药物预防体系研究
Linsong Liu,Gang Yuan,Fuyan Sun et al.
Linsong Liu et al.
To better deliver antiretroviral drugs for treating patients with acquired immune deficiency syndrome (AIDS) with poor immune reconstitution, a novel nanopole capsule was designed in this study. Forty-eight patients with AIDS with poor immu...
Co-Encapsulation of Violacein and Iron Oxide in Poly(lactic acid) Nanoparticles for Simultaneous Antibacterial and Anticancer Applications [0.03%]
紫花素和氧化铁在聚乳酸纳米颗粒中的共封装以实现同时抗菌和抗癌作用
Maria Kanelli,Bahram Saleh,Thomas J Webster et al.
Maria Kanelli et al.
To date, the possibility of drug-resistant bacterial infections in hospitals and intensive care units comprises a significant concern especially for immunocompromised cancer patients. In the current study, violacein and superparamagnetic ir...
Poly d,l-(lactic-co-glycolic) Acid PEGylated Isoliquiritigenin Alleviates Traumatic Brain Injury by Reversing Cyclooxygenase 2 Level [0.03%]
聚-D,L-（乳酸-co-乙醇酸）-PEG异黄酮通过逆转环氧化酶2水平来缓解脑外伤
Zhengyang Li,Chao Xu,Yan Wang
Zhengyang Li
As a severe neurological disease of trauma, traumatic brain injury (TBI) leads to other disorders, such as depression, dementia and epilepsy. This study investigated whether poly d,l-(lactic-co-glycolic) acid (PLGA) PEGylated isoliquiritige...
Study on the Expression of β-1,3-N-acetylglucosaminyltransferase 3 in Gastric Cancer and the Mechanism Promoting Gastric Cancer Progression Based on the Extraction Method of Nanomagnetic Beads [0.03%]
基于纳米磁珠提取法的β-1，3-N-乙酰氨基葡萄糖转移酶3在胃癌中的表达及促进胃癌进展机制的研究
Huijun Zhou,Jinfeng Zhao,Xiaolin Yang et al.
Huijun Zhou et al.
The oncogenic role of β-1,3-N-acetylglucosaminyltransferase 3 (B3GNT3) in several cancers is well documented. However, the expression, function, and mechanism of B3GNT3 in gastric cancer (GC) remain to be investigated. Here, we extracted R...
Engineering PD-L1 Cellular Nanovesicles Encapsulating Epidermal Growth Factor for Deep Second-Degree Scald Treatment [0.03%]
工程PD-L1细胞纳米囊泡递送表皮生长因子治疗深度烧伤创面修复的研究
Xiao-Feng Zhu,Dan-Dan Su,Xin-Hui Tian et al.
Xiao-Feng Zhu et al.
Scars are common and intractable consequences after scalded wound healing, while monotherapy of epidermal growth factors does not solve this problem. Maintaining the stability of epidermal growth factors and promoting scarless healing of wo...
Two-Photon Nanoprobe for NIR-II Imaging of Tumour and Biosafety Evaluation [0.03%]
用于肿瘤近红外二区成像的双光子纳米探针及其生物安全评价
Yiqian Zha,Xinyuan Cui,Yanlei Liu et al.
Yiqian Zha et al.
How to develop near-infrared second window (NIR-II, 1000-1700 nm) fluorescent nanoprobes with a uniform size, strong fluorescence signal and good biosafety owns great clinical requirement. Herein we reported that a two photon fluorescent na...
3D-Printed Bionic Titanium Alloy Artificial Lamina Prevents Epidural Adhesion and Restores the Stability After Laminectomy in Pigs [0.03%]
用于防治术后硬膜粘连及经椎板切除术后恢复脊柱稳定的生物钛合金假椎板的3D打印研究(猪)
Jianwen Li,Zhongjia He,Xianyin Liu et al.
Jianwen Li et al.
Laminectomy can cause the dura mater to adhere to the surrounding scar tissue, leading to soft spinal stenosis after surgery. Although artificial laminae are considered ideal substitutes, they present challenges such as insecure fixation an...