A New Gold Nanoparticles and Paclitaxel Co-Delivery System for Enhanced Anti-Cancer Effect Through Chemo-Photothermal Combination [0.03%]
一种新型的金纳米颗粒和紫杉醇共递送系统通过化疗与光热治疗结合增强抗肿瘤效应
Honglei Zhan,Wenjing Song,Mingyang Gu et al.
Honglei Zhan et al.
Limited chemotherapeutic efficiency, drug resistance and side effect are primary obstacles for cancer treatment. The development of co-delivery system with synergistic treatment modes should be a promising strategy. Here, we fabricated a mu...
Colorimetric Aptasensor Based on Fe₃O₄-Cu2+ Nanozyme with Intrinsic Peroxidase-Like Activity in the Detection of Breast Cancer Exosomes [0.03%]
基于Fe₃O₄-Cu²⁺纳米酶本征类过氧化物酶活性的乳腺癌外泌体比色适配子传感器
Jian Long,Fang Wang,Guohua Zha et al.
Jian Long et al.
Because breast cancer cells such as MCF-7, exhibit vital and developmental signs by exosome secretion, diagnosing them in the blood can provide a good index of the presence of breast cancer. However, accurate and inexpensive detection of ex...
A Time-Course Evaluation of DNA Damage and Neurotoxicity Induced by PEGylated Graphene Oxide Nanoparticle in Swiss Albino Mice [0.03%]
聚乙二醇化氧化石墨烯纳米颗粒诱导瑞士白色裸小鼠DNA损伤和神经毒性的动态评估研究
Nojood Altwaijry,Qura Tul Ain,Hissah Alnuwaysir et al.
Nojood Altwaijry et al.
PEGylated graphene oxide nanoparticle (PEG-nGO) has been commonly used as a carrier for therapeutic drugs and vaccines, because of its unique properties, such as high solubility, more stability and increased biocompatibility in physiologica...
Enhanced Glioblastoma Selectivity of Harmine via the Albumin Carrier [0.03%]
通过白蛋白载体增强 harmine 对胶质母细胞瘤的选择性
Shi-Hui Liu,Qing-Zhen Wang,Tao Liu et al.
Shi-Hui Liu et al.
Glioblastoma, the most common tumor in the brain, has witnessed very little clinical progress over the last decades. Exploring and discovering new therapeutic strategies for glioblastoma has become a critical problem. Harmine (HM), belongin...
Inhibiting Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variants: Targeting the Spike and Envelope Proteins Using Nanomaterial Like Peptides [0.03%]
利用类似肽的纳米材料抑制严重急性呼吸系统综合症冠状病毒2（SARS-CoV-2）变体：针对刺突蛋白和包膜蛋白进行靶向治疗
Alaa F Nahhas,Alrayan F Nahhas,Abdulrahman A Alshaikh et al.
Alaa F Nahhas et al.
Coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused significant death, economic crisis, and the world to almost completely shut down. This present study focused on targeting the...
Two New 3D Supramolecular Complexes: Photocatalytic Properties and Treatment Activity for Gastric Cancer [0.03%]
两种新的三维超分子复合物：光催化性质及胃癌治疗活性研究
Jiangkun Lu,Wei Yu,Guoguo Ji et al.
Jiangkun Lu et al.
Two new coordination polymers, [Cu₂(5-MeO-Hip)₄(py)₄]n (1) and [Co(5-EtO-ip)(4,4'-bipy)]n·n(MeOH) (2) (5-MeO-H₂ip is 5-methoxyisophthalic acid, 5-EtO-H₂ip is 5-ethoxyisophthalic acid, py is pyridine, and 4,4'-bipy is 4,4'-bipyridine),...
Synchronous Signal Transmission Method of Minimally Invasive Renal Failure Surgery Based on Nano Molecular Image Probe [0.03%]
基于纳米分子影像探针的微创肾衰手术同步信号传递方法
Fu Zheng,Dan Tian,Dan Chen et al.
Fu Zheng et al.
The synchronous signal transmission can promote the successful completion of minimally invasive renal failure surgery, so the synchronous signal transmission method of minimally invasive renal failure surgery based on nano molecular image p...
The Application of Sensitive Nano-Confined Nanoparticle System Using siRNA Targeting Extracellular Signal-Regulated Kinase (ERK)/Mitogen-Activated Protein Kinase (MAPK) Pathway in Gastrointestinal Cancer [0.03%]
基于siRNA靶向细胞外信号调节激酶(MEK)/丝裂原活化蛋白激酶(MAPK)通路的敏感型纳米限域纳米粒系统在胃肠肿瘤中的应用研究
Runda Wu,Shan Tong,Mohammad Saeed Kahrizi et al.
Runda Wu et al.
In this study we tried to develop a Sensitive Nano-Confined Nanoparticles (S-NCN) system using siRNA against Programmed death-ligand 1 (PDL-1) and Polo Like Kinase 1 (Plk1) to treat gastrointestinal cancer. In this regard, we first synthesi...
Antibacterial Properties of Ag-Cu Alloy Nanoparticles Against Multidrug-Resistant Pseudomonas aeruginosa Through Inhibition of Quorum Sensing Pathway and Virulence-Related Genes [0.03%]
银铜合金纳米颗粒通过抑制群体感应途径和毒力相关基因对抗多重耐药铜绿假单胞菌的抗菌性能
Mozhgan Pourjafari,Masood Ghane,Hami Kaboosi et al.
Mozhgan Pourjafari et al.
Objective: To evaluate the application of Ag-Cu NPs as quorum sensing (QS) inhibitors and attenuate virulence expression to overcome the global crisis of multidrug-resistant (MDR) P. aeruginosa. Methods: Ag-Cu NPs were synthesized by co-red...
Helal F Al-Harthi,Abu Baker,Abdallah M Elgorban et al.
Helal F Al-Harthi et al.
Transition metal oxide NPs have delivered wide applications in various fields. Therefore, in this study, a novel fungus, Alternaria sp. (NCBI Accession No: MT982648) was isolated and characterized from the vicinity of medicinal plants. Even...