Preparation and Biocompatibility Evaluation of Nanoscale Isoniazide-Loaded Mineralized Collagen Implants for Tuberculous Bone and Joint Repair [0.03%]
用于结核性骨和关节修复的纳米异烟肼矿化胶原植入物的制备及生物相容性评价
Xu Fang,Jun-Feng Dong,Qian Wang et al.
Xu Fang et al.
Bone and joint tuberculosis is an extremely severe infectious disease that commonly occurs due to the primary infection of a type of mycobacteria, called Mycobacterium tuberculosis. Under the current scenario, there are very limited supplie...
Enhanced Antibacterial Activity of Indocyanine Green-Loaded Graphene Oxide via Synergistic Contact Killing, Photothermal and Photodynamic Therapy [0.03%]
通过协同接触杀灭、光热和光动力疗法增强的吲哚菁绿/氧化石墨烯复合材料抗菌活性
Yuan Chen,Wenlong Huang,Yuanhao Dong et al.
Yuan Chen et al.
Methicillin-resistant Staphylococcus aureus (MRSA) has become a serious threat to human's health. Recently, photodynamic/photothermal therapy (PDT/PTT) has emerged as promising strategies against antibiotics-resistant pathogens due to their...
Hyaluronic Acid-Melatonin Nanoparticles Improve the Dysregulated Intestinal Barrier, Microbiome and Immune Response in Mice with Dextran Sodium Sulfate-Induced Colitis [0.03%]
透明质酸-褪黑素纳米颗粒可改善葡聚糖硫酸钠诱导的小鼠结肠炎的肠道屏障、菌群和免疫失调状况
Wanghui Jing,Min Zhu,Fushuo Wang et al.
Wanghui Jing et al.
Although the cause of inflammatory bowel disease (IBD) is unclear, current studies have found that the main factors involved in its pathogenesis include imbalance of mucosal immune response, intestinal dysbiosis, and destruction of the inte...
Lateral Flow Strip Assay for Detection of Mycoplasma hyorhinis Based on a Pair of Sandwich-Type Aptamers [0.03%]
基于一对夹心型适配体的猪鼻支原体 lateral flow 条检测法
Yibin Zhang,Jing Dai,Yuan Yang et al.
Yibin Zhang et al.
Mycoplasma hyorhinis is a normal flora in swine respiratory tract and also often found in multiple human tumor tissues, which is considered to be highly correlated with human tumors. Due to the detection of Mycoplasma hyorhinis mainly relie...
Prostate-Specific Membrane Antigen-1-Mediated Au@SiO₂@Au Core-Shell Nanoparticles: Targeting Prostate Cancer to Enhance Photothermal Therapy and Fluorescence Imaging [0.03%]
基于前列腺特异性膜抗原的金@硅 dioxide@金核壳型纳米颗粒：提高荧光成像引导的前列腺肿瘤光热治疗的靶向性
Ruizhi Wang,Guofeng Zhou,Yuchan Yang et al.
Ruizhi Wang et al.
The advantages of deep tissue penetration and the high spatial accuracy of photothermal therapy have been widely studied. Gold, as a photothermal material, has received particular attention. Different sizes and shapes of gold have been stud...
Hyaluronic Acid Modified Curcumin-Loaded Chitosan Nanoparticles Inhibit Chondrocyte Apoptosis to Attenuate Osteoarthritis via Upregulation of Activator Protein 1 and RUNX Family Transcription Factor 2 [0.03%]
透明质酸修饰的姜黄素载壳聚糖纳米颗粒通过上调活化蛋白1和RUNX家族转录因子2抑制软骨细胞凋亡以减轻骨关节炎
Jian Wang,Liaoran Zhang,Jiaxue Zhu et al.
Jian Wang et al.
Hyaluronic acid (HA) and curcumin (CUR) have been previously utilized for osteoarthritis (OA) treatment. CUR-loaded chitosan nanoparticles (CUR@CS NPs) and HA CUR@CS NPs were synthesized in our research to ascertain the synergistic impacts ...
Study on the Influence of Shear Stress and Pulse Electrical Stimulation to the Growth of Cardiomyocytes [0.03%]
剪切力及脉冲电刺激对心肌细胞生长影响的研究
Junwei Xu,Limin Feng,Jingxi Wang et al.
Junwei Xu et al.
Engineered myocardial tissue is expected to be used in the treatment of myocardial defects and other diseases, and one of the keys is to construct a suitable environment for the culture of myocardial tissue in vitro. In this study, flow she...
Reactive Oxygen Species-Responsive Polyether Micelle Nanomaterials for Targeted Treatment of Ulcerative Colitis [0.03%]
用于溃疡性结肠炎靶向治疗的响应型氧自由基的聚醚胶束纳米材料
Xin-Xin Zhao,Shan-Bo Ma,Jin-Peng Wen et al.
Xin-Xin Zhao et al.
As one of the most challenging inflammatory diseases, the incidence of ulcerative colitis (UC) is increasing year by year, but the existing therapeutic drugs are not effective and lack of targeting. Nanomaterials are expected to become prom...
Effect of Hypoxia-Inducible Factor-1 α on Osteogenesis of Titanium Dioxide Nanotube Bone Marrow Mesenchymal Stem Cells with Different Diameters Under Periodic Tensile Stress [0.03%]
缺氧诱导因子-1α对不同直径二氧化钛纳米管表面骨髓间充质干细胞周期拉伸应力下的成骨效应的影响
Yu Meng,Juwu Chen,Xuejian Wu
Yu Meng
Bone marrow mesenchymal stem cells (BMSC) have the ability to multi polarize with multiple tropisms and participate in tissue remodeling. This study assessed the effect of titanium dioxide nanotubes with different diameters on ossification ...
Itraconazole for Topical Treatment of Skin Carcinogenesis: Efficacy Enhancement by Lipid Nanocapsule Formulations [0.03%]
伊曲康唑的皮肤局部给药抗肿瘤作用及脂质纳米囊壳技术对其疗效的增效研究
Nabila A El-Sheridy,Riham M El-Moslemany,Alyaa A Ramadan et al.
Nabila A El-Sheridy et al.
Itraconazole (ITC), an antifungal drug with anticancer activity, shows potential for oral treatment of skin cancer. There is clinical need for topical ITC for treating low-risk skin carcinogenesis. Our objective was to develop ITC nanoformu...