Nanoparticles with Optimal Ratiometric Co-Delivery of Docetaxel with Gambogic Acid for Treatment of Multidrug-Resistant Breast Cancer [0.03%]
用于治疗耐多药乳腺癌的具有最佳比率共输送多西他赛和 Garcinia xanthone gambogic acid 纳米颗粒
Youwei Xu,Changyuan Wang,Yanfang Ding et al.
Youwei Xu et al.
It has been reported that gambogic acid (GA), the main active component of gamboge, could directly inhibit and reduce the expression level of P-gp by promoting protein degradation through post-translational proteasome pathway. In this study...
Nanotheranostic Based Iron Oxide (Fe₃O₄) Saturated Lactoferrin Nanocapsules for Colonic Adenocarcinoma [0.03%]
基于铁oxide（Fe₃O₄）饱和乳铁蛋白纳米囊的纳码放疗诊断治结合结肠腺癌治疗
Sishir K Kamalapuram,Rupinder K Kanwar,Jagat R Kanwar
Sishir K Kamalapuram
Efficient early detection of cancer and its simultaneous therapy can improve the survival of cancer patients significantly. Recently there is great interest for the development of nanotheranostic systems with multimodal live real-time imagi...
Curcumin-Zein Nanospheres Improve Liver Targeting and Antifibrotic Activity of Curcumin in Carbon Tetrachloride-Induced Mice Liver Fibrosis [0.03%]
姜黄素-玉米醇溶蛋白纳米球改善姜黄素在四氯化碳诱导的小鼠肝纤维化中的靶向性和抗纤维化活性
Mardi M Algandaby,Majid M Al-Sawahli,Osama A A Ahmed et al.
Mardi M Algandaby et al.
Liver fibrosis is a major health problem that has no satisfactory medication. Curcumin, (CUR) although known for its antifibrotic activity, has limited medicinal use owing to its poor oral pharmacokinetic properties and targeting efficiency...
Superparamagnetic Iron Oxide Nanorod Carriers for Paclitaxel Delivery in the Treatment and Imaging of Colon Cancer in Mice [0.03%]
超顺形铁氧体纳米棒载 paclitaxel 在小鼠结肠癌治疗与成像中的应用
Khalilalrahman Dehvari,Yun Chen,Ya-Hui Tsai et al.
Khalilalrahman Dehvari et al.
A multifunctional magnetic drug delivery system was developed and explored as an efficient and less invasive technique to improve colon cancer diagnosis and therapy in mice. In this system, superparamagnetic iron oxide nanorod cores enhance...
Improvement of Antitumor Efficacy by Combination of Thermosensitive Liposome with High-Intensity Focused Ultrasound [0.03%]
温敏脂质体与高强度聚焦超声联合增效抗肿瘤作用研究
Jae Min Cha,Dong Gil You,Eun Jung Choi et al.
Jae Min Cha et al.
High intensity focused ultrasound (HIFU), allowing for precise heating of the deep and local area, is emerging as the source of mild hyperthermia for delivery of doxorubicin (DOX) using thermosensitive liposomes (TSLs). Conventionally, HIFU...
Gadolinium-Loaded Solid Lipid Nanoparticles as a Tumor-Absorbable Contrast Agent for Early Diagnosis of Colorectal Tumors Using Magnetic Resonance Colonography [0.03%]
用于磁共振结肠镜检查早期诊断结直肠肿瘤的负载 gadolinium 的固体脂质纳米颗粒造影剂及其吸收研究
Jihong Sun,Shizheng Zhang,Shaojie Jiang et al.
Jihong Sun et al.
Magnetic resonance (MR) contrast agents focusing on special functions are required to improve cancer diagnosis, particularly in the early stages. Here, we designed multifunctional solid lipid nanoparticles (SLNs) with simultaneous loading o...
Characterization of the Uptake Efficiency and Cytotoxicity of Tetrandrine-Loaded Poly(N-vinylpyrrolidone)-Block-Poly(ε-caprolactone) (PVP-b-PCL) Nanoparticles in the A549 Lung Adenocarcinoma Cell Line [0.03%]
四神丸载荷聚（N-乙烯基吡咯烷酮）-嵌段-聚（ε-己内酯）纳米粒在A549肺腺癌细胞系中的摄取效率及细胞毒性研究
Huae Xu,Xiaolin Li,Hui Kong et al.
Huae Xu et al.
Tetrandrine (Tet) has been previously reported to induce apoptosis in several cancer cell lines. However, poor Tet solubility has limited its further application. The lipophilicity of Tet suggests that the development of Tet-loaded biodegra...
A pH-Sensitive Nanosystem Based on Carboxymethyl Chitosan for Tumor-Targeted Delivery of Daunorubicin [0.03%]
基于羧甲基壳聚糖的pH敏感型载多柔比星纳米给药系统
Xueqiong Zhang,Hong Zhang,Liangquan Yin et al.
Xueqiong Zhang et al.
Nanoparticles, such as polymeric micelles, are currently regarded as effective drug delivery vehicles. In this study, a series of carboxymethyl chitosan/daunorubicin (CMCS/DNR) conjugates with macromolecular carriers of different molecular ...
Ratiometric Reactive Oxygen Species Nanoprobe for Noninvasive In Vivo Imaging of Subcutaneous Inflammation/Infection [0.03%]
用于无创在体成像皮下炎症/感染的比值型活性氧纳米探针
Jun Zhou,Hong Weng,Yihui Huang et al.
Jun Zhou et al.
Release of reactive oxygen species (ROS) accompanied with acute inflammation and infection often results in cell death and tissue injury. Several ROS-reactive bioluminescent probes have been investigated in recent years to detect ROS activi...
Ratiometric Reactive Oxygen Species Nanoprobe for Noninvasive In Vivo Imaging of Subcutaneous Inflammation/Infection [0.03%]
用于无创在体成像皮下炎症/感染的比率型活性氧纳米探针
Jun Zhou,Hong Weng,Yihui Huang et al.
Jun Zhou et al.
Release of reactive oxygen species (ROS) accompanied with acute inflammation and infection often results in cell death and tissue injury. Several ROS-reactive bioluminescent probes have been investigated in recent years to detect ROS activi...