Effect of Porous Zirconia Coating on Human Gingival Fibroblasts and Its Mechanism [0.03%]
多孔氧化锆涂层的生物相容性及机制研究
Jiangqi Hu,Yue Qie,Yu Luo et al.
Jiangqi Hu et al.
Gingival fibroblasts play an important role in the constitution of soft tissue attachment. This study aims to investigate whether porous zirconia coating has a positive effect on promoting human gingival fibroblast attachment. The porous zi...
Research on Mechanism of Nanometric Bone Pulp Activated with Double Gene as Bone Morphogenetic Protein 1 and Vascular Endothelial Growth Factor for Improving the Strength of Centrum in Osteoporosis [0.03%]
纳米骨髓素活化双基因（骨形态发生蛋白1和血管内皮生长因子）机制研究改善骨质疏松症椎体强度
Cheng-Liang Zhang,Da-Jiang Song,Li-Dong Zhang et al.
Cheng-Liang Zhang et al.
The aim of this study was assessing the mechanism of nanometric bone pulp activated with double gene as bone morphogenetic protein 1 (BMP-1) and vascular endothelial growth factor (VEGF) in improving the strength of centrum in osteoporosis ...
Yu Fu,Xufei Bian,Pingrong Li et al.
Yu Fu et al.
With the rapid development of nanotechnology, carrier-based nano-drug delivery systems (DDSs) have been widely studied due to their advantages in optimizing pharmacokinetic and distribution profiles. However, despite those merits, some carr...
Cyclovirobuxine D Brain-Targeted Liposomes Improve Cerebral Ischemia-Reperfusion Injury via Anti-Oxidant Stress and Activating Autophagy [0.03%]
脑靶向 Cyclovirobuxine D 磷脂复合体通过抗氧化应激和激活自噬改善缺血再灌注脑损伤
Fang Yang,Lingzhi Ren,Tuo Liu et al.
Fang Yang et al.
One of the main issues faced by nervous system diseases is that drugs are difficult to enter the brain. The previous study suggested that Cyclovirobuxine D (CVBD) encapsulated in Angiopep-conjugated Polysorbate 80-Coated Liposomes showed a ...
Protective Effect of Iron Oxide Nanoparticles on Periodontal Injury in Rats by Inhibiting Collagenase-1 and Alkaline Phosphatase Expression [0.03%]
铁纳米颗粒通过抑制明胶酶-1和碱性磷酸酶的表达对大鼠牙周病损伤具有保护作用
Yirui Wang,Zhixiong Liang,Liang Chen et al.
Yirui Wang et al.
This study intends to assess whether iron oxide nanoparticles affect periodontal injury and collagenase-1 (COL-1), and alkaline phosphatase (ALP) in rats. In this study, the ALP activity and Col-1 concentration in rats with periodontal inju...
Targeting the Conserved Sequence of the Substrate for the Proteinase of Severe-Acute-Respiratory-Syndrome-Coronavirus-2 (SARS-CoV-2) Using Nano-Networks: Efficacy, Stability, and No Cytotoxicity [0.03%]
利用纳米网络针对严重急性呼吸系统综合症冠状病毒2型（SARS-CoV-2）蛋白酶底物的保守序列：有效、稳定且无细胞毒性
Alaa F Nahhas,Thomas J Webster
Alaa F Nahhas
Herein, we designed a nano peptide that contains three important motifs for targeting the chemotrypsin-like cysteine protease (3CLpro) which is the enzyme responsible for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) replicat...
Ferromagnetic Vortex Iron Oxide Nanorings Modified with Integrin β 1 Antibody for Targeted MRI Tracking of Human Mesenchymal Stem Cells [0.03%]
一种用于人骨髓间充质干细胞磁共振标记成像的整合素β 1抗体修饰的铁氧化物纳米环血管造影剂
Yujie Wang,Yinjuan Lv,Yuxuan Li et al.
Yujie Wang et al.
Mesenchymal stem cells (MSCs) have demonstrated great potential for tissue engineering and regenerative medicine applications. Noninvasive and real-term tracking of transplanted MSCs in vivo is crucial for studying the distribution and migr...
Targeted Therapy of Lung Adenocarcinoma by the Nanoplatform Based on Milk Exosomes Loaded with Paclitaxel [0.03%]
基于乳液纳米递送平台的肺腺癌精准治疗研究
Junge Chen,Fengqiang Cao,Yang Cao et al.
Junge Chen et al.
Lung cancer is the most common cancer throughout the world. Currently, most lung cancer therapies are still limited by serious side effects caused. This paper reports a biocompatible drug delivery system that utilizes milk-derived exosomes ...
Novel Au-Se Nanoprobes for Specific Thrombin Detection in Diagnosis of Lung Cancer [0.03%]
用于肺癌诊断的新型Au-Se纳米探针特异性纤溶酶检测
Koujun Zhu,Rongguo Lu,Weifeng Qu et al.
Koujun Zhu et al.
Thrombin is associated with malignant tumors and promotes tumor development, metastasis, and angiogenesis, therefore its identification especially in lung cancer cells is crucial. Because the interference of in vivo biothiols caused false p...
Resveratrol Nanoparticles Suppresses Migration and Invasion of Renal Cell Carcinoma Cells by Inhibiting Matrix Metalloproteinase 2 Expression and Extracellular Signal-Regulated Kinase Pathway [0.03%]
白藜芦醇纳米颗粒通过抑制基质金属蛋白酶2表达和细胞外信号调节激酶途径抑制肾细胞癌的迁移和侵袭
Xing-Wang Zhu,Feng-Ming Dong,Jia Liu et al.
Xing-Wang Zhu et al.
The aim of this study was to examine the impact of Resveratrol nanoparticles on migration/invasion capacity of renal cell carcinoma (RCC) cells and its mechanism. Human RCC cells were exposed to dimethyl sulfoxide or gradient concentrations...