DNA vaccination for cervical cancer; a novel technology platform of RALA mediated gene delivery via polymeric microneedles [0.03%]
用于宫颈癌的DNA疫苗;通过聚合物微针递送RalA介导的基因传递新技术平台
A A Ali,C M McCrudden,J McCaffrey et al.
A A Ali et al.
HPV subtypes (16, 18) are associated with the development of cervical cancer, with oncoproteins E6 and E7 responsible for pathogenesis. The goal of this study was to evaluate our 'smart system' technology platform for DNA vaccination agains...
Synthesis and characterization of Au@SiO2core-shell nanostructures for improved antibiotic delivery systems [0.03%]
用于改善抗生素输送系统的金@二氧化硅核壳纳米结构的合成与表征
Agata Kowalska,Elżbieta Adamska,Anna Wcisło et al.
Agata Kowalska et al.
Gold nanoparticles (Au NPs) are widely used in medicine, however, their tendency to agglomerate can increase toxicity, which is a significant limitation. To counteract this, they are covered with a neutral coating, e.g. silica, which, among...
Nanoformulation-enabled CDDP/ICG combination for synergistic chemotherapy and photothermal therapy of ovarian cancer [0.03%]
纳米制剂联合CDDP和ICG协同化疗和光热治疗卵巢癌
Qidan Huang,Jingsong Huang,Ting Deng et al.
Qidan Huang et al.
Ovarian cancer (OC) remains a highly lethal gynecologic malignancy, with platinum (Pt)-based chemotherapy facing challenges from drug resistance and systemic toxicity. In this study, we developed a silica-based nanoparticle system, termed S...
Design and optimization of diacerein loaded lipid nanocarriers: Characterization, in vitro and in vivo evaluation for anti-arthritic activity [0.03%]
设计和优化二月桂酸阿西醇脂质纳米载体:表征及抗关节炎活性的体内外评价
Swarupananda Mukherjee,Priya Ghosh,Saheli Naskar et al.
Swarupananda Mukherjee et al.
Solid lipid nanoparticles (SLNPs) are recognised as dependable substitute for conventional polymeric nanocarriers for lipophilic drugs. Here, diacerein (DC) (BCS class II drug) loaded SLNPs were developed via solvent evaporation technique f...
Corrigendum to "A novel bidirectional perfusion-like administered system for NIR-II fluorescence imaging precision diagnosis of bladder cancer" [Nanomed Nanotechnol Biol Med 49 (April 2023) 102661] [0.03%]
关于“一种新型双向灌注类似给药系统用于近红外二区荧光成像精准诊断膀胱癌”的勘误[Nanomedicine: Nanotechnology, Biology and Medicine 49 (2023年4月) 102661]
Shilei Ren,Rong Dai,Ziliang Zheng et al.
Shilei Ren et al.
Multidimensional successively targeted glucose-aptamer nano-system to achieve "Point-Surface" early intervention of Alzheimer's disease [0.03%]
多维度递级靶向葡萄糖-适配体纳米系统实现阿尔茨海默病“点面结合”的早期干预
Jie Zhou,Xiaomeng Dong,Junfen Feng et al.
Jie Zhou et al.
Difficulties such as low blood-brain barrier (BBB) permeability, insufficient accumulation of lesions and late treatment stage lead to difficulties in the treatment of Alzheimer's disease (AD). In this paper, a successively targeted polydop...
Photodynamic immunotherapy with checkpoint inhibitor-loaded nanogels: A synergistic frontier in cancer nanomedicine [0.03%]
负载检查点抑制剂的纳米凝胶用于光免疫疗法:癌症纳米医学中的协同前沿技术
Yue Song
Yue Song
Advances in nanogel engineering have ushered in a new era of precision immunotherapy by enabling the coordinated delivery of photosensitizers and immune checkpoint inhibitors (ICIs) in solid tumors. This review examines the mechanistic and ...
Emerging nanocarrier platforms in cervical cancer therapy: From molecular targeting to precision nanomedicine [0.03%]
宫颈癌治疗中的新兴纳米递送平台:从分子靶向到精准纳米医药
Samidha Singh,Naman Batra,Saurabh Mittal
Samidha Singh
Background: Cervical cancer being a significant global health burden, for which conventional treatments like surgery, chemotherapy, and radiotherapy are limited by poor tumour specificity, systemic toxicity, infertility, ...
Erratum to "the effects of TPGS-modified liposomal ginger extract in the treatment of acetic acid-induced ulcerative colitis in rats" [Nanomedicine: Nanotechnology, biology and medicine, volume 72, March 2026, 102903] [0.03%]
关于“TPGS修饰的姜提取物脂质体对乙酸诱导的大鼠溃疡性结肠炎治疗作用的研究”的勘误[Nanomedicine: Nanotechnology, biology and medicine, volume 72, March 2026, 102903]
Zakieh Keshavarzi,Sonia Fathi-Karkan,Ali Siahposht- Khachaki et al.
Zakieh Keshavarzi et al.
Cisplatin(IV)-fatty acid prodrug-bound albumin nanoparticles: In vitro, in silico, and in vivo evaluation in breast cancer therapy [0.03%]
用于乳腺癌治疗的顺铂(IV)-脂肪酸前药结合的人血清白蛋白纳米粒:体外、计算机模拟及体内评价
Oly Katari,Vivek Yadav,R Rajkumar et al.
Oly Katari et al.
The therapeutic outcome of cisplatin (CP) in triple-negative breast cancer (TNBC) is hindered by irreversible protein binding, systemic toxicities, and resistance development. Therefore, we synthesized three CP(IV) prodrugs of fatty acids (...