Electrospun silk fibroin nanofibers enriched with metallic nanoparticles and phenolic acids for antimicrobial applications [0.03%]
负载金属纳米粒子和酚酸的静电纺丝丝素纳米纤维的抗菌性能研究
Monika Śmigielska,Dominika Pawcenis,Dorota Majda et al.
Monika Śmigielska et al.
Current trends in the development of the next generation of advanced wound dressings are directed toward the use of natural polymeric materials with additional properties such as antimicrobial function, controlled permeability, renewability...
Biomimetic lipid nanoparticles mediated metabolic regulation and sonodynamic therapy for glioblastoma immunotherapy [0.03%]
仿生脂质纳米颗粒介导代谢调节和声动力治疗用于胶质母细胞瘤免疫治疗
Tiezheng Mo,Faming Huang,Yu Tian et al.
Tiezheng Mo et al.
Regulation of the tumor microenvironment (TME) represents a promising strategy to enhance immunotherapy for glioblastoma (GBM) immunotherapy. Lactate dehydrogenase A (LDHA) is an attractive metabolic target for TME modulation. We developed ...
Chemo-physical loading of exosomes on porous titanium for improved soft tissue integration [0.03%]
化疗物理负载的外泌体在多孔钛上的加载以促进软组织整合
Dan Zou,Fanfan Dai,Xue Zhou et al.
Dan Zou et al.
Establishing a durable soft tissue seal around dental implants is critical for preventing peri-implantitis, yet efficient loading of exosomes onto titanium surfaces remains challenging. Here, a dual-functional coating was developed on anodi...
Multifunctional theranostic nanoplatform based on HER2-specific liposomes loaded with IR783 for simultaneous PTT/PDT therapy and optical bioimaging [0.03%]
一种基于HER2特异性脂质体负载IR783的多功能诊疗一体纳米平台用于光热/动力联合治疗及光学成像
E I Shramova,A Yu Frolova,E V Serova et al.
E I Shramova et al.
We propose a new multifunctional nanoplatform for intravital optical bioimaging and combined photodynamic and photothermal therapy of HER2-positive cancers, using single-wavelength laser irradiation. The system consists of IR783-loaded lipo...
Superparamagnetic core-shell nanoparticles enable co-delivery of psoralen and paclitaxel for the treatment of triple-negative breast cancer [0.03%]
超顺磁性核壳型纳米颗粒用于苯alen和紫杉醇共递送治疗三阴性乳腺癌的研究
Manling Du,Fengjie Liu,Lin Shi et al.
Manling Du et al.
Triple-negative breast cancer (TNBC) therapy with paclitaxel (PTX) is hampered by systemic toxicity, drug resistance, and poor delivery efficiency when combined with psoralen (PSO). In this study, paclitaxel/psoralen-loaded magnetic composi...
Demeng Xiang,Xiao Feng,Jinfeng Zhang
Demeng Xiang
Eye inflammation, including dry eye disease, uveitis, and post-operative inflammation, is a major cause of visual impairment worldwide. Conventional ocular therapies are limited by anatomical barriers, rapid tear clearance, and poor tissue ...
Yeast-derived vacuoles as potential therapeutic agents for modulating neuroinflammation in Alzheimer's disease [0.03%]
酵母衍生的液泡作为潜在的治疗剂用于调节阿尔茨海默病中的神经炎症
Han T N Nguyen,Yoon-Young Hwang,Ra-Mi Park et al.
Han T N Nguyen et al.
Neuroinflammation is a major contributor to Alzheimer's disease (AD) pathology, including amyloid precursor protein (APP)/amyloid-beta (Aβ)-associated protein expression and Tau phosphorylation. Here, we evaluated yeast-derived vacuoles as...
Rationally designed, synthesized, and characterized the anti-PD-L1 peptide conjugated temozolomide self-assembled prodrug nanoparticle for targeted lung cancer chemoimmunotherapy [0.03%]
合理设计、合成和表征了抗PD-L1肽结合的替莫唑胺自组装前药纳米颗粒用于靶向肺癌化免疫疗法
Sakuntala Gayen,Soumendra Nath Bandyopadhyay,Sandipan Dasgupta et al.
Sakuntala Gayen et al.
Lung cancer remains foremost cause of cancer-related deaths worldwide. Over the past decade, conventional monotherapies frequently limited by therapeutic resistance and dose-limiting toxicity. To address these limitations, the present study...
Macrophage membrane-biomimetic nanoparticles for targeted delivery of melatonin in myocardial ischemia-reperfusion injury [0.03%]
仿巨噬细胞膜纳米粒子介导的褪黑素心肌缺血再灌注损伤靶向治疗研究
Tian Huang,Zewei Zhang,Ruoyu Hou et al.
Tian Huang et al.
Myocardial ischemia-reperfusion injury (MIRI) remains a major clinical challenge following the restoration of blood flow after ischemic events in the heart. Excessive reactive oxygen species production during this process exacerbates cellul...
Corrigendum to "Functional engineered mesenchymal stem cells with fibronectin‑gold composite coated catheters for vascular tissue regeneration" [Nanomed: Nanotechnol Biol Med 14 (2018) 699-711] [0.03%]
“用于血管组织再生的纤维连接蛋白-金复合物涂层导管的功能工程化间充质干细胞”的订正([纳米医学：纳米技术生物医学杂志14(2018)699-711])
Yun-Wen Chen,Shu-Chen Hsieh,Yi-Chin Yang et al.
Yun-Wen Chen et al.