Treatment of Hypercalcemic Hyperparathyroidism After Kidney Transplantation Is Associated With Improved Allograft Survival [0.03%]
肾移植后高钙血症性 hyperparathyroidism的治疗与移植物存活率提高相关
Rongzhi Wang,Rhiannon D Reed,Griffin Price et al.
Rongzhi Wang et al.
Background: Hyperparathyroidism (HPT) and malignancy are the most common causes of hypercalcemia. Among kidney transplant (KT) recipients, hypercalcemia is mostly caused by tertiary HPT. Persistent tertiary HPT after KT i...
Real-World Outcomes of Trastuzumab Deruxtecan in Patients With HER2+ Metastatic Breast Cancer: The DE-REAL Study [0.03%]
DESTINY-Breast06真实世界研究：T-DMB治疗HER2阳性转移性乳腺癌患者的预后
Andrea Botticelli,Roberta Caputo,Simone Scagnoli et al.
Andrea Botticelli et al.
Background: Trastuzumab deruxtecan (T-DXd) demonstrated unprecedented efficacy in patients with pretreated HER2+ metastatic breast cancer (mBC). However, few data are available about its efficacy in routine clinical pract...
Multicenter Study
The oncologist. 2024 Apr 4;29(4):303-310. DOI:10.1093/oncolo/oyad308 2024
Head and Neck Squamous Cell Carcinoma of Unknown Primary: A Diagnostic Work-Up [0.03%]
未知原发灶头颈部鳞状细胞癌的诊断工作流程
Meenakkshy Manoharan,Noah S Kalman,Guilherme Rabinowits
Meenakkshy Manoharan
The current work-up of the primary tumor site of a head and neck squamous cell carcinoma of unknown primary is not standardized and results in several time-consuming procedures that delay treatment initiation. This article seeks to consolid...
Prognostic Role of p53 Immunohistochemical Status in Invasive Breast Cancer. A Retrospective Review of 1387 Cases With Luminal-Like/Her2 Negative Breast Tumors [0.03%]
p53免疫组化状态在侵袭性乳腺癌中的预后作用：1387例 luminal-like/her2阴性肿瘤的回顾分析
Gerti Dajti,Margherita Serra,Giovanni Cisternino et al.
Gerti Dajti et al.
Purpose: The aim of this study was to evaluate the prognostic role of p53 immunohistochemical (IHC) expression in a large cohort of patients with hormone receptors (HR)-positive/Her2-negative primary invasive breast cance...
Patient-Reported Outcomes of Accelerated Aging: A Novel Approach to Investigate Second Cancer Risk in Adolescent and Young Adult (18-39 Years) Cancer Survivors [0.03%]
早发性癌症幸存者（18-39岁）二次癌风险的新研究方法：基于患者报告结果的加速衰老模型
Daniël J van der Meer,Susan Zevenbergen,Carla Vlooswijk et al.
Daniël J van der Meer et al.
Background: Adolescent and young adult cancer survivors (AYAs, aged 18-39 years at first diagnosis) have a higher second cancer risk. Accelerated aging is hypothesized as underlying mechanism and has been described clinic...
Abdul Rafae,Frits van Rhee,Samer Al Hadidi
Abdul Rafae
The treatment of multiple myeloma has evolved significantly over the past few decades with the development of novel therapeutics. The introduction of proteasome inhibitors, immunomodulatory drugs, monoclonal antibodies, and high-dose chemot...
Hydration Methods for Cisplatin Containing Chemotherapy: A Systematic Review [0.03%]
顺铂化疗的水化方法：一项系统评价研究
Charlotte Sikking,Kelly L Niggebrugge-Mentink,A S Elise van der Sman et al.
Charlotte Sikking et al.
Introduction: Cisplatin-induced nephrotoxicity (CIN) can be prevented by fluid hydration, electrolyte supplementation, or forced diuresis; however, the best way to prevent CIN is still unknown. The aim of this study was t...
Clinical and Genotypic Insights Into Higher Prevalence of Palbociclib Associated Neutropenia in Asian Patients [0.03%]
palbociclib相关性粒细胞减少症在亚洲患者中更为高发的临床及基因型研究见解
Jiun-I Lai,Ting-Hao Kuo,Kuan-Jung Huang et al.
Jiun-I Lai et al.
Background: CDK4/6 inhibitors (CDK4/6i) have shown great efficacy in prolonging progression-free survival and is the current standard of care for hormone positive (HR(+)) metastatic breast cancer (mBC). Despite well toler...
Association of Neutrophil-to-Lymphocyte Ratio and Absolute Lymphocyte Count With Clinical Outcomes in Advanced Breast Cancer in the MONARCH 2 Trial [0.03%]
MONARCH 2试验中难治性乳腺癌患者中性粒细胞与淋巴细胞比值和临床结局的关系
Eriko Tokunaga,Yasuo Miyoshi,Koji Dozono et al.
Eriko Tokunaga et al.
Background: Established prognostic factors for treatment response to cyclin-dependent kinases 4 and 6 inhibitors are currently lacking. We aimed to investigate the relationship of pretreatment neutrophil-to-lymphocyte rat...