Luis G Medina,Firas Hatoum,Nahuel Paesano et al.
Luis G Medina et al.
Penile squamous cell carcinoma (PSCC) is a rare malignancy that displays profound disparities in incidence, access to care, and clinical outcomes rooted in economic, social differences, and cultural practices. PSCC has been linked to high t...
Joy Li,Leslie Ballas,Pooja Ghatalia
Joy Li
Muscle-invasive bladder cancer (MIBC) has historically been managed with neoadjuvant cisplatin-based chemotherapy followed by radical cystectomy (RC), a strategy associated with substantial morbidity and long-term quality-of-life implicatio...
Balancing Cure and Quality of Life: Navigating Functional Outcomes in Localized Prostate Cancer [0.03%]
兼顾治愈与生活质量：局限性前列腺癌的功能预后管理
Abby L Grier,Erik Briers,Randie E White et al.
Abby L Grier et al.
Current guidelines for clinically localized prostate cancer offer a wide range of management options, from active surveillance to surgery and radiation therapy (RT). Treatment selection depends on tumor characteristics, overall health, and ...
Neoadjuvant Systemic Therapy in Kidney and Bladder Cancer: Current Evidence and Emerging Paradigms [0.03%]
肾癌和膀胱癌的新辅助全身治疗：现有证据与新范式
Rana R McKay,Asha Tipirneni,Rick Bangs et al.
Rana R McKay et al.
Neoadjuvant systemic therapy has emerged as a strategy to improve outcomes in high-risk localized genitourinary malignancies. In bladder cancer, neoadjuvant cisplatin-based chemotherapy with or without immunotherapy is standard of care, wit...
Beyond Chronologic Age: Frailty, Geriatric Assessment, and Personalized Care for Older Adults With Genitourinary Cancer [0.03%]
超越年龄：老年泌尿系统癌症患者的脆弱性、老年评估和个性化护理
Peter L Lee,Carla Fitch,Jason A Efstathiou et al.
Peter L Lee et al.
Frailty captures multiple physical, mental, and social vulnerabilities that affect older adults with cancer and is associated with clinical outcomes. A major challenge in oncology is how best to avoid undertreatment or overtreatment by tail...
Yi Song,Meenakshi Jeeva,Robert P Liddell et al.
Yi Song et al.
Approximately 25% of patients with colorectal cancer present with metastatic disease to the liver at diagnosis, and about 50% develop liver metastases at some point during the course of the disease. Surgical resection of hepatic metastases ...
Contemporary Multidisciplinary Treatment of Borderline-Resectable and Locally Advanced Pancreatic Adenocarcinoma [0.03%]
当代局部晚期和潜在可切除胰腺导管腺癌的综合治疗
Rachel H Joung,Rebecca A Snyder
Rachel H Joung
Pancreatic ductal adenocarcinoma remains a highly lethal malignancy, with borderline resectable (BRPC) and locally advanced pancreatic cancer (LAPC) representing biologically and anatomically complex subsets requiring coordinated multidisci...
Organ Preservation for Gastroesophageal Junction and Gastric Cancers: Ready for Primetime? [0.03%]
食管胃结合部癌和胃癌的器官保存治疗：准备就绪吗？
Winta Mehtsun,Lola Van Doosselaere,Ugwuji N Maduekwe
Winta Mehtsun
Organ preservation for gastroesophageal junction (GEJ) and gastric cancers is emerging as an attainable-but still selective-therapeutic goal. The convergence of effective systemic therapy, enhanced imaging, and endoscopic sophistication has...
Erratum: Decoding Clinical Trials in Metastatic Breast Cancer: Practical Insights for Optimal Therapy Sequencing [0.03%]
metastatic乳腺癌临床试验解读：制定最佳治疗顺序的实用见解.erratum
Chiara Corti,Hope S Rugo,Sara M Tolaney
Chiara Corti
Mikolaj Filon,Bogdana Schmidt
Mikolaj Filon