Precursor Hematologic Conditions: Diagnosis, Risk Stratification, Clinical Implications, and Management [0.03%]
前驱血液系统疾病：诊断、风险分层、临床意义和管理
Yuxin Liu,Pinkal Desai,Omar Nadeem et al.
Yuxin Liu et al.
Hematologic precursor conditions include monoclonal gammopathy of undetermined significance (MGUS), monoclonal B-cell lymphocytosis (MBL), and clonal hematopoiesis (CH). These conditions are characterized by a clonal expansion of either pla...
Challenges and Opportunities for Global Cervical Cancer Elimination: How Can We Build a Model for Other Cancers? [0.03%]
全球消除宫颈癌的挑战与机遇：如何建立其他癌症的防控模式？
Clement Adebamowo,Paolo Giorgi Rossi,Philip E Castle
Clement Adebamowo
Cervical cancer remains a leading cause of cancer-related death among women globally, despite the availability of effective prevention through human papillomavirus (HPV) vaccination and HPV-based screening. This review explores the state-of...
Martin Palmeri,Eric J McNulty,Alti Rahman et al.
Martin Palmeri et al.
Patient-centered physician-directed care is facing unprecedented challenges. Escalating health care spending on low-value services with a focus on managing disease rather than promoting health is leading to increasing financial toxicity to ...
Artificial Intelligence for Head and Neck Squamous Cell Carcinoma: From Diagnosis to Treatment [0.03%]
人工智能在头颈部鳞状细胞癌的诊疗中扮演的角色
Bolin Song,Ipsa Yadav,Jillian C Tsai et al.
Bolin Song et al.
Head and neck squamous cell carcinoma (HNSCC) remains a globally prevalent malignancy with high morbidity and mortality. Despite therapeutic advances, patient outcomes are hindered by tumor heterogeneity, treatment-related toxicity, and the...
Kathleen N Moore,Joyce F Liu,Domenica Lorusso
Kathleen N Moore
Therapeutic advances across the gynecologic cancer continuum have resulted in improvements in patient care and outcomes over the past decade, yet challenges remain. In ovarian cancer, the evolution of poly (ADP-ribose) polymerase (PARP) inh...
Long-Term Follow-Up Care After Treatment for Primary Breast Cancer: Strategies and Considerations [0.03%]
乳腺癌治疗后的长期随访护理：策略与考虑因素
Maria Alice Franzoi,Wolfgang Janni,Jessica Erdmann-Sager et al.
Maria Alice Franzoi et al.
Advancements in early detection and multimodal treatment strategies have significantly improved survival rates for early-stage breast cancer, now exceeding 80% at 10 years. However, breast cancer survivors (BCS) often experience persistent ...
Breast and Gynecologic Cancer Care for Sexual Minority Women and Transgender People [0.03%]
性少数女性和跨性别者的乳腺癌和妇科癌症护理
Gabrielle Mayer,Alberto Giovanni Leone,Olivia Korostoff-Larsson et al.
Gabrielle Mayer et al.
Sexual and gender minority (SGM) individuals continue to experience disparities in cancer risk, screening, treatment, and outcomes. Despite advances following the 2017 ASCO recommendations, inequities persist, driven by systemic barriers, s...
Fauzia Riaz,Joshua J Gruber,Melinda L Telli
Fauzia Riaz
Triple-negative breast cancer (TNBC) was first described as a distinct disease entity 20 years ago. Since that time, there has been tremendous effort invested in understanding the clinical features and biology of this breast cancer subtype ...
Moving Away From Standard Induction in Newly Diagnosed Acute Myeloid Leukemia [0.03%]
急性髓系白血病初始诱导治疗向非标准方案转变
Maire Okoniewski,Jesus Gonzalez Lugo,Tara L Lin
Maire Okoniewski
Anthracycline and cytarabine chemotherapy has been the backbone of induction chemotherapy for AML for more than 50 years. Advances in our understanding of leukemia biology and the development of targeted agents against leukemia driver mutat...
Chimeric Antigen Receptor T-Cell Therapy and Bispecific Antibody Use in Earlier Lines of Treatment of Large B-Cell Lymphoma, Follicular Lymphoma, and Mantle Cell Lymphoma [0.03%]
嵌合抗原受体T细胞疗法和双特异性抗体在大B细胞淋巴瘤、滤泡性淋巴瘤和套细胞淋巴瘤早期治疗线中的应用
Imran A Nizamuddin,Armin Ghobadi
Imran A Nizamuddin
Cellular therapies, including chimeric antigen receptor T-cell therapy and bispecific antibodies (BsAbs), have revolutionized the treatment of various B-cell non-Hodgkin lymphomas. A number of agents are now approved by regulatory agencies ...