Phosphate levels and blood pressure in incident hemodialysis patients: a longitudinal study [0.03%]
血透患者血磷水平与血压的纵向研究
Cindy Xin Huang,Laura C Plantinga,Nancy E Fink et al.
Cindy Xin Huang et al.
An elevated serum phosphate level in hemodialysis patients has been associated with mineral deposition in blood vessels. We studied a possible physiologic consequence of hyperphosphatemia by examining the relation between serum phosphate le...
Bone morphogenetic protein 7 (BMP7): a critical role in kidney development and a putative modulator of kidney injury [0.03%]
骨形态发生蛋白7(BMP7)在肾脏发育中的关键作用及其可能对肾脏损伤的调节作用
Patrick Archdeacon,Randal K Detwiler
Patrick Archdeacon
Bone morphogenetic protein 7 (BMP7), a member of the tumor growth factor beta superfamily, appears to have a role in both kidney development and response to kidney injury. Signals through its pathways permit both epithelial differentiation ...
Garabed Eknoyan
Garabed Eknoyan
Acute kidney injury (AKI), a recently defined clinical entity, is an ailment that has afflicted humans from time immemorial. Its emergence as a disease follows by 50 years that of acute renal failure (ARF) after the Second World War. The me...
Ryan Goldberg,Paula Dennen
Ryan Goldberg
Acute kidney injury (AKI) is common in the intensive care unit and is associated with significant morbidity and mortality. Based on the RIFLE criteria, AKI occurs in up to 67% of patients in the intensive care unit (ICU), with approximately...
Sarah Faubel
Sarah Faubel
The development of respiratory failure in patients with AKI is a particularly devastating consequence that greatly increases patient mortality. When respiratory failure and AKI occur together, the mortality is greater than 80%. A clear unde...
Progression from acute kidney injury to chronic kidney disease: a pediatric perspective [0.03%]
急性肾损伤发展至慢性肾脏病的进展：儿科视角
Stuart L Goldstein,Prasad Devarajan
Stuart L Goldstein
Although emerging evidence indicates that the incidence of both acute kidney injury (AKI) and chronic kidney disease (CKD) in children is rising and the etiologies are dramatically changing, relatively little is currently known regarding th...
Mark Stafford-Smith,Uptal D Patel,Barbara G Phillips-Bute et al.
Mark Stafford-Smith et al.
Kidney dysfunction is common after cardiac surgery and predicts mortality risk and poorer long-term outcome, particularly when acute injury superimposes upon chronic kidney disease. Numerous insults contribute to perioperative renal impairm...
Sri G Yarlagadda,Christina L Klein,Alkesh Jani
Sri G Yarlagadda
Delayed graft function (DGF) describes dysfunction of the kidney allograft immediately after transplantation and is the most common complication in the immediate posttransplantation period. Although a standardized definition for DGF is lack...
Renal replacement therapy in acute kidney injury: intermittent versus continuous? How much is enough? [0.03%]
急性肾损伤的肾脏替代治疗：间断与连续？多少剂量足够？
Josée Bouchard,Charlotte Weidemann,Ravindra L Mehta
Josée Bouchard
Approximately 4% of all critically ill patients will require renal replacement therapy (RRT). Despite its potential reversibility, acute kidney injury has a significant impact on morbidity and mortality. Numerous studies have addressed the ...
Charles L Edelstein
Charles L Edelstein
The diagnosis of acute kidney injury (AKI) is usually based on measurements of blood urea nitrogen (BUN) and serum creatinine. BUN and serum creatinine are not very sensitive or specific for the diagnosis of AKI because they are affected by...