Alexandra Le Bras
Alexandra Le Bras
The link between stress and hyperactivity in a marmoset model of autism [0.03%]
用于自闭症的小型狨猴模型中的压力与过度活跃之间的联系
Jorge Ferreira
Jorge Ferreira
The adrenal stress response involves distinct dynamics of both cortisol and corticosterone in the axolotl salamander [0.03%]
墨西哥步行仙蟾的肾上腺压力反应涉及皮质醇和皮质酮的动力学差异
Anita Dittrich,Sofie Amalie Andersson,Emil A B Winkel et al.
Anita Dittrich et al.
The axolotl is a popular model organism in regenerative biology owing to its ability to regenerate amputated limbs and internal organs. The role of injury-derived signals in initiating the regenerative response is still not well understood,...
Thinking outside the boxes: analyzing the current landscape of popular behavioral tests for adult zebrafish [0.03%]
跳出思维定势:分析当前热门成年斑马鱼行为测试的现状
Allan V Kalueff,Adam Michael Stewart,Murilo S de Abreu et al.
Allan V Kalueff et al.
Methods for randomized, blinded, controlled evaluation of putative disease interventions in multilaboratory, preclinical assessment networks [0.03%]
多实验室临床前评估网络中潜在疾病干预措施的随机盲法对照评价方法
Jessica Lamb,Karisma Nagarkatti,Marcio A Diniz et al.
Jessica Lamb et al.
Science faces a reproducibility crisis, and public trust in science declines when large clinical trials, which had been qualified by promising preclinical studies, fail. While some clinical trial designs may have been inadequate, preclinica...
Retinal phenotype of APOB100 transgenic mice on a Western diet with human-like hyperlipidemia and cholesterol crystals in the retina and choroid [0.03%]
载人APOB100转基因小鼠的视网膜表型及其西方饮食引起的类人类高脂血症和视网膜脉络膜胆固醇结晶沉着
Nicole El-Darzi,Tim F Dorweiler,Natalia Mast et al.
Nicole El-Darzi et al.
Drusen and subretinal drusenoid deposits, the pathognomonic lesions for age-related macular degeneration (AMD), are rich in cholesterol. Yet, AMD is not consistently linked to plasma lipids. Here wild-type and human apolipoprotein B100-expr...
PiggyBac-mediated transgenesis and CRISPR-Cas9 knockout in the greater wax moth, Galleria mellonella [0.03%]
大蜡螟(Galleriamellonella)的PiggyBac介导的转基因和CRISPR-Cas9敲除
James C Pearce,Jennie S Campbell,Joann L Prior et al.
James C Pearce et al.
The larvae of the greater wax moth, Galleria mellonella, are gaining prominence as a versatile nonmammalian in vivo model to study host-pathogen interactions. Their ability to be maintained at 37 °C, coupled with a broad susceptibility to ...
Jorge Ferreira
Jorge Ferreira
Alexandra Le Bras
Alexandra Le Bras
Jorge Ferreira
Jorge Ferreira