Distinct endocannabinoids specifically signal to astrocytes or neurons in the adult mouse hippocampus [0.03%]
几种不同的内源大麻素特异性地作用于成年小鼠海马区的星形胶质细胞或神经元
Jose Antonio Noriega-Prieto,Rafael Falcón-Moya,Jacob A Noeker et al.
Jose Antonio Noriega-Prieto et al.
The endocannabinoid (eCB) system is involved in many processes in brain function. eCBs depress synaptic transmission by directly activating presynaptic CB1 receptors (CB1Rs), and they indirectly potentiate adjacent synapses by activating as...
An open science resource for accelerating scalable digital health research in autism and other neurodevelopmental conditions [0.03%]
一个开放的科学资源加速自闭症和其他神经发育障碍的可扩展数字健康研究
Micha Hacohen,Adam Levy,Hadas Kaiser et al.
Micha Hacohen et al.
The Simons Sleep Project (SSP) is an open-science resource designed to accelerate digital health research into sleep and daily behaviors of autistic children. The SSP contains data from Dreem3 EEG headbands, multi-sensor EmbracePlus smartwa...
Fractal analysis of brain shape formation predicts age and genetic similarity in human newborns [0.03%]
分形分析预测新生儿大脑形状、年龄和遗传相似性
Stephan Krohn,Amy Romanello,Nina von Schwanenflug et al.
Stephan Krohn et al.
The neonatal period represents a critical phase of human brain development. During this time, the brain shows a dramatic increase in size, but how its morphology emerges in early life remains largely unknown. Here we show that human newborn...
Dynamic subtype- and context-specific subcellular RNA regulation in growth cones of developing neurons of the cerebral cortex [0.03%]
发育中大脑皮层神经元生长锥中的动态亚型和上下文特异性细胞RNA调节
Priya Veeraraghavan,Anne K Engmann,John J Hatch et al.
Priya Veeraraghavan et al.
Neurons of distinct subtypes compartmentalize subtype-specific function in part by differentially localizing and translating specific RNAs, but underlying mechanisms are not understood. Here we investigate messenger RNA localization and sta...
Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals [0.03%]
睡眠依赖的超慢节律在爬行动物和哺乳动物间具有保守性
Antoine Bergel,Julien M Schmidt,Baptiste Barrillot et al.
Antoine Bergel et al.
By recording brain activity in seven lizard species, humans, rats and pigeons, we demonstrate an infraslow brain rhythm during sleep in all species. This rhythm is tightly coupled with eye movements, muscle tone, heart and breathing rate in...
Charting brain morphology in international healthy and neurological populations [0.03%]
国际健康和神经疾病人群脑形态图表研究
Zhizheng Zhuo,Li Chai,Yinshan Wang et al.
Zhizheng Zhuo et al.
Quantifying individual deviations in brain morphology from normative references is useful for understanding neurodiversity and facilitating personalized management of brain health. Here we report Chinese brain normative references using mor...
Recommendations for the inclusion and study of sex and gender in research [0.03%]
关于在研究中纳入和探讨性别和性别的建议
David P Finn,Brian E McGuire,Simon Beggs et al.
David P Finn et al.
Sex and gender are important variables in research, but they are inconsistently explored. The international PAINDIFF Network makes 13 recommendations for studying sex and gender as variables in pain research, which are applicable across the...
Charles D Nichols
Charles D Nichols
Chloé Maëlle Benoit,Dan Alin Ganea,Ricardo Paricio-Montesinos et al.
Chloé Maëlle Benoit et al.
The axon initial segment (AIS) is the site of action potential generation and exhibits structural and functional plasticity upon adaptation of neuronal excitability and disease. Performing in vivo longitudinal two-photon imaging of AIS in t...
Rethinking the centrality of brain areas in understanding functional organization [0.03%]
重构大脑区域的核心性以理解其功能组织
Benjamin Yost Hayden,Sarah R Heilbronner,Seng Bum Michael Yoo
Benjamin Yost Hayden
Parcellation of the cerebral cortex into functionally modular brain areas is foundational to cognitive and systems neuroscience. Here, we question the central status of brain areas from the perspectives of neuroanatomy and electrophysiology...