Dermal Safety of Tapinarof Cream 1%: Results From 4 Phase 1 Trials [0.03%]
浓度为1%的塔皮纳罗夫乳膏的皮肤安全性：4项一期试验结果
John Jett,Michael McLaughlin,Timothy Wilson et al.
John Jett et al.
Background: Tapinarof (VTAMA®; Dermavant Sciences, Inc.) is a novel, non-steroidal, topical, aryl hydrocarbon receptor agonist, FDA approved for psoriasis treatment and under investigation for atopic dermatitis treatm...
Long-Term Efficacy and Safety of Omalizumab Monotherapy in a Patient With Normocomplementemic Urticarial Vasculitis [0.03%]
omalizumab单药治疗正常补体介导的血管性荨麻疹1例长期疗效及安全性观察
Mohamed Abuzakouk,Omar Ghorab,Rajaie Namas et al.
Mohamed Abuzakouk et al.
Normocomplementemic urticarial vasculitis is a rare autoimmune disorder characterized by leukocytoclasia, fibrin deposits, and extravasated erythrocytes affecting multiple organ systems. Current treatment modalities, including corticosteroi...
A Narrative Review of Nicotinamide Adenine Dinucleotide (NAD)+ Intermediates Nicotinamide Riboside and Nicotinamide Mononucleotide for Keratinocyte Carcinoma Risk Reduction [0.03%]
烟酰胺单核苷酸和烟酰胺核糖用于降低角质细胞癌风险的叙事综述
Benjamin Kahn,Mimi Borrelli,Tiffany Libby
Benjamin Kahn
Oral nicotinamide (NAM) supplementation has been shown to decrease the incidence of keratinocyte carcinoma (KC) in high-risk skin cancer patients. NAM is a nicotinamide adenine dinucleotide (NAD+) intermediate and thus directly leads to inc...
A Retrospective Review of Tofacitinib in the Treatment of Refractory Dermatomyositis [0.03%]
托法替尼治疗难治性皮肌炎的回顾性研究
John Plante,Chelsea Eason,Gabriella Santa Lucia et al.
John Plante et al.
Dermatomyositis (DM) is an autoimmune myopathy with characteristic dermatologic features.1 Tofacitinib is an immunomodulator with proven efficacy against numerous immune-mediated disorders, including rheumatoid arthritis (RA) and psoriasis....
A Retrospective Study of Calcinosis Cutis in Patients With Systemic Lupus Erythematosus [0.03%]
系统性红斑狼疮患者(calcinosis cutis)钙磷沉积病的回顾性研究
Janice Tiao,Rebecca Gaffney,Flavia Fedeles
Janice Tiao
Calcinosis cutis (CC) is a very rare and poorly characterized finding in systemic lupus erythematosus (SLE).1 In this retrospective study, we present our experience of 10 individuals with SLE who developed CC, describing the epidemiology, d...
Supplement Article: Skin Barrier Deficiency in Rosacea: An Algorithm Integrating OTC Skincare Products Into Treatment Regimens [0.03%]
玫瑰痤疮皮肤屏障缺损补充分析：非处方护肤品整合治疗算法
Hilary Baldwin,Andrew Alexis,Anneke Andriessen et al.
Hilary Baldwin et al.
Introduction: Rosacea is a chronic condition involving inflammation leading to a diminished skin barrier function in sebaceous gland-rich facial skin. The current algorithm represents part II of a series investigating sim...
Supplement Article: The Role of Epidermal Barrier Dysfunction and Cutaneous Microbiome Dysbiosis in the Pathogenesis and Management of Acne Vulgaris and Rosacea [0.03%]
附录文章：皮肤屏障功能障碍和皮肤病原微生物群失调在寻常痤疮和玫瑰痤疮发病机制和治疗中的作用
Justin Marson,Neal Bhatia,Emmy Graber et al.
Justin Marson et al.
Background: Dysregulation of either the cutaneous microbiome (CM) or epidermal barrier function (EBF) is thought to play an increasingly important role in acne vulgaris (AV) and rosacea pathogenesis. ...
Supplement Article: Dysbiosis, (Barrier) Dysfunction, and Dermatoses: A Chicken-and-Egg Dilemma [0.03%]
附：皮肤屏障功能与皮肤病的病因：“先有鸡还是先有蛋”的两难问题
Justin Marson,Hilary Baldwin
Justin Marson
Acne vulgaris (AV) and rosacea are two of the most common dermatoses diagnosed and managed by dermatologists.1,2 Despite this and our improved understanding of the unique pathogenesis of each, there has been little focus on general skin car...
Perioral Rejuvenation: Evaluation of Safety and Efficacy of High Molecular Weight Hyaluronic Acid and Amino Acid Treatment [0.03%]
高分子量透明质酸和氨基酸治疗的的安全性和有效性评估在 perioral 面部区域的年轻化中的应用
Irina Poleva
Irina Poleva
Background: The lips and perioral area play a crucial role in facial aesthetics. Signs of aging, such as wrinkles, decreased muscle tone, and thinning skin, frequently appear first in this anatomical area and, subsequentl...
Observational Study
Journal of drugs in dermatology : JDD. 2022 Sep 1;21(9):968-973. DOI:10.36849/JDD.6875 2022
Celine Phong,Gabrielle Baker,Melody Esmaeili et al.
Celine Phong et al.
Background: In addition to hair loss, alterations in hair texture can be a worrisome side effect of certain medications yet are seldom reported and poorly characterized. ...