Clinical Evaluation of Thiamidol-Containing Formulations for the Visual Management of Facial Hyperpigmentation [0.03%]
含噻氨基药物剂型治疗面部色素沉着的临床评价
Seemal R Desai,Edward Ted Lain,Nada Elbuluk et al.
Seemal R Desai et al.
Background: Cutaneous hyperpigmentation, which includes melasma, post-inflammatory hyperpigmentation, and solar lentigines, significantly impacts patients' quality of life. The overproduction of melanin is mediated by act...
Randomized Controlled Trial
Journal of drugs in dermatology : JDD. 2025 Dec 1;24(12):1195-1202. DOI:10.36849/JDD.9517 2025
Skin Improvements in Acne Vulgaris Patients Using Gel-Matrix Moisturizer as a Complement to Topical Treatments [0.03%]
作为局部治疗补充使用的凝胶基质润肤剂可改善寻常痤疮患者的皮肤状态
Katrina T Bernhardt,Erin Zaleski,Wen-Hwa Li et al.
Katrina T Bernhardt et al.
Background: A novel gel-matrix moisturizer was designed to 1) deliver immediate, long-lasting hydration benefits in a lightweight, non-greasy, noncomedogenic formula that is suitable for use on dry, oily, acne-prone, and ...
Impact of Low-Dose Oral Minocycline (DFD-29) on Skin, Gastrointestinal, and Vaginal Microflora in Healthy Adults [0.03%]
低剂量口服二甲胺四环素（DFD-29）对健康成人皮肤、肠道及阴道菌群的影响
Richard L Gallo,Hilary Baldwin,Julie Harper et al.
Richard L Gallo et al.
Background: DFD-29 (minocycline hydrochloride extended-release capsules, 40 mg) has shown significant therapeutic benefit vs placebo and doxycycline in treating moderate-to-severe rosacea. However, the impact of its use o...
Randomized Controlled Trial
Journal of drugs in dermatology : JDD. 2025 Dec 1;24(12):1222-1230. DOI:10.36849/JDD.9245 2025
GLP-1 Receptor Agonists in Hidradenitis Suppurativa: A Novel Therapeutic Approach for Hidradenitis Suppurativa and Its Comorbidities [0.03%]
人胰高血糖素样肽-1受体激动剂在毛囊炎中的应用：毛囊炎及其合并症的新型治疗方法研究
Sawyeh Maher,Michael H Gold
Sawyeh Maher
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder associated with many comorbidities, including obesity, diabetes, cardiovascular risk factors, mental health issues, and many more disorders...
Report From the 2024 International Dermatology Outcome Measures (IDEOM) Annual Meeting [0.03%]
2024年国际皮肤病结局测量（IDEOM）年度会议报告
Sarah Romanelli,Gretchen D Ball,Arianna J Zhang et al.
Sarah Romanelli et al.
Background: International Dermatology Outcome Measures (IDEOM) is a nonprofit organization committed to advancing the development and accessibility of evidence-based, consensus-driven outcome measures in dermatology. This...
Evaluating the Risk of Atherosclerotic Cardiovascular Disease in Inflammatory Skin Disease: Insights From a TriNetX Cohort Study [0.03%]
评估炎症性皮肤病患者动脉粥样硬化心血管疾病风险：TriNetX队列研究的启示
Neal Gupta,Kayla Zafar,Jennifer Wang et al.
Neal Gupta et al.
Objective: Recognizing the risk of atherosclerotic cardiovascular disease (ASCVD) in patients is crucial in clinical practice. Recent studies suggest an association between inflammatory skin diseases and ASCVD. This study...
Clindamycin Phosphate 1.2%/Adapalene 0.15%/ Benzoyl Peroxide 3.1% Gel for Moderate-to-Severe Acne: A Pooled Analysis by Age [0.03%]
克林霉素磷酸酯/ adapalene/过氧苯甲酰凝胶治疗中重度痤疮的年龄分层汇总分析
Leon H Kircik,Julie C Harper,Hilary Baldwin et al.
Leon H Kircik et al.
Background: Acne pathophysiology and presentation may differ between pediatric/adolescent/young adult (9-24 years) and adult (≥25 years) patients. Fixed-dose clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide ...
An Open-Label, Single-Center Proof of Concept Study Evaluating the Efficacy and Safety of Tirzepatide for Moderate to Severe Hidradenitis Suppurativa [0.03%]
评估 tirzepatide 治疗中度至重度汗腺炎有效性和安全性的开放性单中心概念验证研究
Ana Sofia Acosta-Madiedo,Marcela Gutierrez,Martha Gutierrez et al.
Ana Sofia Acosta-Madiedo et al.
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory disease associated with obesity and metabolic dysregulation. Current therapies yield variable benefits and do not target metabolic drivers. Tirzepatide, ...
More Than Skin Clearance: Connecting Brodalumab's Mechanism of Action to Patient Outcomes in Psoriasis [0.03%]
从机制到疗效：布罗利单抗治疗银屑病患者的临床价值研究
John Koo,George Han,Mark Lebwohl et al.
John Koo et al.
Psoriasis has profound negative impacts on quality of life (QOL), including stigmatization, discrimination, occupational challenges, and mental health concerns, which are correlated with disease severity. Effective, long-term symptom contro...
Isotretinoin Does Not Increase the Risk of Inflammatory Bowel Disease: A TriNetX Retrospective Cohort Analysis [0.03%]
异维A酸不会增加炎症性肠病的风险：TriNetX回顾性队列分析
Neal Gupta,Maile Ray,Ashley Shayya et al.
Neal Gupta et al.
Background: Background: The increasing use of long-term, low-dose isotretinoin for acne has raised concerns about a potential association with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative col...