Cariology Clinical Trials: What Are We-and What Should We Be-Looking At? [0.03%]
齿科学临床试验：我们看到了什么-以及我们应该看什么？
N P T Innes
N P T Innes
Randomized control trial (RCT) methodology has compared interventions for the prevention and management of dental caries since the late 1960s. Despite almost 50 years and evidence of significant wastage within the wider biomedical research ...
A C R Tanner,C A Kressirer,S Rothmiller et al.
A C R Tanner et al.
The oral microbiome plays a critical role in maintaining oral health. Frequent dietary carbohydrate intake can lead to dysbiosis of the microbial community from overproduction of acid with selection for increases in acidogenic, acid-toleran...
M Alkilzy,R M Santamaria,J Schmoeckel et al.
M Alkilzy et al.
Modern approaches in caries treatment involve lesion management without tissue removal. Regenerative medicine focuses on replacing damaged tissues with biologically similar tissues. This article discusses the scientific evidence and clinica...
Fluoride Use in Health Care Settings: Association with Children's Caries Risk [0.03%]
医疗环境下氟化物的使用与儿童患龋风险的关系
M Fontana,G J Eckert,M A Keels et al.
M Fontana et al.
Expanded partnership with the medical community is an important strategy for reducing dental caries disparities. The purpose of this study was to assess the relationship between fluoride (F) "in office" (drops/tablets and/or varnish), as pr...
Multicenter Study
Advances in dental research. 2018 Feb;29(1):24-34. DOI:10.1177/0022034517735297 2018
M M Nascimento
M M Nascimento
Carious lesions develop in tooth surfaces where there is an imbalance of the processes of acid and alkali production by supragingival biofilms. Since low pH is the main driving factor in the development of carious lesions, most efforts to i...
In Sickness and in Health-What Does the Oral Microbiome Mean to Us? An Ecological Perspective [0.03%]
疾病相伴，健康管理口腔微生物有何意义？生态学视角分析
P D Marsh
P D Marsh
The oral microbiome is natural and has a symbiotic relationship with the host by delivering important benefits. In oral health, a dynamic balance is reached between the host, the environment, and the microbiome. However, the frequent intake...
Changes in Caries Risk in a Practice-Based Randomized Controlled Trial [0.03%]
牙科实践基础上的随机对照试验中的龋齿风险变化趋势
P Rechmann,B W Chaffee,B M T Rechmann et al.
P Rechmann et al.
To demonstrate that Caries Management by Risk Assessment (CAMBRA) can be successfully implemented in dental practice, 30 dentists were recruited to perform a 2-y CAMBRA trial. Twenty-one dentists (18 private practices, 3 community clinics) ...
Randomized Controlled Trial
Advances in dental research. 2018 Feb;29(1):15-23. DOI:10.1177/0022034517737022 2018
Getting to Know "The Known Unknowns": Heterogeneity in the Oral Microbiome [0.03%]
探秘“已知的未知”——口腔微生物组的异质性
R A Burne
R A Burne
Technological advances in DNA sequencing have provided unprecedented insights into the composition of the oral microbiome in health and disease, and RNA-sequencing and metabolomics-related technologies are beginning to yield information on ...
Introduction to ICNARA 3 [0.03%]
ICNARA 3序章
M Fontana,M Wolff,J D Featherstone
M Fontana
Managing Carious Lesions: Consensus Recommendations on Carious Tissue Removal [0.03%]
龋病管理：共识推荐去除龋源性组织
F Schwendicke,J E Frencken,L Bjørndal et al.
F Schwendicke et al.
The International Caries Consensus Collaboration undertook a consensus process and here presents clinical recommendations for carious tissue removal and managing cavitated carious lesions, including restoration, based on texture of deminera...