G Schmalz,S Krifka,H Schweikl
G Schmalz
Unreacted monomers released from dental resin-based composites at non-cytotoxic concentrations cause a depletion of glutathione and an increase of reactive oxygen species (ROS), leading to, e.g., DNA damage and apoptosis. ROS-sensitive MAP-...
M-J Staquet,F Carrouel,J-F Keller et al.
M-J Staquet et al.
Initial sensing of infection is mediated by germline-encoded pattern-recognition receptors (PRRs), the activation of which leads to the expression of inflammatory mediators responsible for the elimination of pathogens and infected cells. PR...
P R Cooper,J L McLachlan,S Simon et al.
P R Cooper et al.
Characterization of the molecular response under caries lesions requires a robust and reliable transcript isolation system, and analysis of data indicated that collection of extracted teeth in either liquid nitrogen/RNA-stabilizing solution...
A F Fouad
A F Fouad
Pulp regeneration is considered in cases where the dental pulp has been destroyed because of microbial irritation. Diverse oral and food-borne micro-organisms are able to invade the pulp space, form biofilm on canal walls, and infiltrate de...
TWIST1 promotes the odontoblast-like differentiation of dental stem cells [0.03%]
TWIST1促进牙髓干细胞向类成牙本质细胞分化
Y Li,Y Lu,I Maciejewska et al.
Y Li et al.
Stem cells derived from the dental pulp of extracted human third molars (DPSCs) have the potential to differentiate into odontoblasts, osteoblasts, adipocytes, and neural cells when provided with the appropriate conditions. To advance the u...
Dental pulp stem cells, niches, and notch signaling in tooth injury [0.03%]
牙髓干细胞、生态位和牙齿损伤的 notch 信号通路
T A Mitsiadis,A Feki,G Papaccio et al.
T A Mitsiadis et al.
Stem cells guarantee tissue repair and regeneration throughout life. The decision between cell self-renewal and differentiation is influenced by a specialized microenvironment called the 'stem cell niche'. In the tooth, stem cell niches are...
M Goldberg
M Goldberg
Differences between pulp repair and regeneration guide different strategic options. After mild carious dentin lesions, odontoblasts and Hoehl's cells are implicated in the formation of reactionary dentin. Reparative dentin formation and/or ...
Global oral health inequalities: task group--implementation and delivery of oral health strategies [0.03%]
全球口腔健康不平等：执行和传递口腔健康战略任务组
A Sheiham,D Alexander,L Cohen et al.
A Sheiham et al.
This paper reviews the shortcomings of present approaches to reduce oral diseases and inequalities, details the importance of social determinants, and links that to research needs and policies on implementation of strategies to reduce oral ...
Global oral health inequalities: challenges in the prevention and management of orofacial clefts and potential solutions [0.03%]
全球口腔健康不平等：唇腭裂防治挑战及潜在解决方案
P A Mossey,W C Shaw,R G Munger et al.
P A Mossey et al.
The birth prevalence of orofacial clefts, one of the most common congenital anomalies, is approximately one in 700 live births, but varies with geography, ethnicity, and socio-economic status. There is a variation in infant mortality and ac...
Global oral health inequalities in incidence and outcomes for oral cancer: causes and solutions [0.03%]
口腔癌发病率和结局的全球口腔健康不平等：原因与解决办法
N W Johnson,S Warnakulasuriya,P C Gupta et al.
N W Johnson et al.
The mouth and oropharynx are among the ten most common sites affected by cancer worldwide, but global incidence varies widely. Five-year survival rates exceed 50% in only the best treatment centers. Causes are predominantly lifestyle-relate...