Next-generation sequencing approaches to understanding the oral microbiome [0.03%]
下一代测序技术在理解口腔微生物组中的应用
E Zaura
E Zaura
Until recently, the focus in dental research has been on studying a small fraction of the oral microbiome-so-called opportunistic pathogens. With the advent of next-generation sequencing (NGS) technologies, researchers now have the tools th...
R A Burne,L Zeng,S J Ahn et al.
R A Burne et al.
Recent rapid advances in "-omics" technologies have yielded new insights into the interaction of the oral microbiome with its host. Associations of species that are usually considered to be acid-tolerant with caries have been confirmed, whi...
M A R Buzalaf,M T Kato,A R Hannas
M A R Buzalaf
This review discusses the role of matrix metalloproteinases (MMPs) in the development of dentin erosion and the protective effects of MMP inhibitors, based on recent evidence from in vitro and in situ studies. MMPs are present in both denti...
N Schlueter,T Jaeggi,A Lussi
N Schlueter
Dental erosion is the non-carious dental substance loss induced by direct impact of exogenous or endogenous acids. It results in a loss of dental hard tissue, which can be serious in some groups, such as those with eating disorders, in pati...
Remineralization agents - new and effective or just marketing hype? [0.03%]
remineralization剂——真正有效的新产品还是营销噱头？
R J M Lynch,S R Smith
R J M Lynch
This is a review of the need for better remineralization and of the status of calcium-based remineralizing agents for use in anti-caries toothpastes. Use of fluoride toothpastes has markedly reduced caries. However, the decline may be over ...
M W J Dodds,D Chidichimo,M S Haas
M W J Dodds
Most surrogate measures of caries were developed to test products containing fluoride, typically at relatively high and closely controlled oral concentrations. However, since the primary mechanism for the remineralization of early enamel ca...
M Hannig,C Hannig
M Hannig
The purpose of this review is to highlight recent nanotechnological developments for remineralization of incipient caries lesions as well as biomimetic strategies for enamel synthesis based on the application of nanotechnology. Analysis of ...
Fluoride plus functionalized β-TCP: a promising combination for robust remineralization [0.03%]
氟化物与功能化β-TCP的组合在再矿化中的应用研究
R L Karlinsey,A M Pfarrer
R L Karlinsey
With more than 50 years of clinical success, fluoride serves as the gold standard agent for preventing tooth decay. In particular, the action of fluoride facilitates saliva-driven remineralization of demineralized enamel and alters solubili...
Calcium phosphopeptides -- mechanisms of action and evidence for clinical efficacy [0.03%]
磷肽钙的作用机制及其临床有效性的证据
N J Cochrane,E C Reynolds
N J Cochrane
Phosphoproteins/phosphopeptides with clusters of acidic residues are found throughout nature, where they aid in the prevention of unwanted precipitation of solid calcium phosphates. The acidic residues, particularly phosphoserine, interact ...
A W G Walls,J H Meurman
A W G Walls
The population of the world is aging. A greater proportion of older people are retaining increasing numbers of natural teeth. Aging is associated with changes in oral architecture and muscle weakness, making personal oral hygiene more diffi...