Atomic force microscopy characterization of white and beige adipocyte differentiation [0.03%]
原子力显微镜观测白色和棕色脂肪细胞分化过程
Alia Mallah,Katerina Stojkova,Ronald N Cohen et al.
Alia Mallah et al.
Adipose tissue plays an essential role in systemic metabolism with white adipose tissue (WAT) making up most of the tissue and being involved in the regulation of energy homeostasis, and brown and beige adipose tissue (BAT) exhibiting therm...
Cedrol alleviates postmenopausal osteoporosis in rats through inhibiting the activation of the NF-κB signaling pathway [0.03%]
CED通过抑制NF-κB信号通路活化治疗绝经后骨质疏松症的作用研究
Zhen Zheng,Ying Fan,Jingyun Zhang et al.
Zhen Zheng et al.
Pharmacological studies have shown that Cedrol (CE) exhibits extensive biological activities, including anti-inflammatory and analgesic. Moreover, it can inhibit the NF-κB pathway and the expression of various associated proteins. This stu...
HSP70 protects PC12 cells against TBHP-induced apoptosis and oxidative stress by activating the Nrf2/HO-1 signaling pathway [0.03%]
HSP70通过激活Nrf2/HO-1信号途径保护TBHP诱导的氧化应激和PC12细胞凋亡
Bo Deng,Xuegang He,Zhaoheng Wang et al.
Bo Deng et al.
HSP70 exhibits neuroprotective, antioxidant, and anti-apoptotic properties, which are crucial in preventing spinal cord injury (SCI) induced by oxidative stress and apoptosis. In this study, we assessed the potential protective effects and ...
Bruton tyrosine kinase degrader BP001 attenuates the inflammation caused by high glucose in raw264.7 cell [0.03%]
布鲁顿酪氨酸激酶降解剂BP001削弱高糖引起的RAW264.7细胞炎症
Jun Lin,Zhendong Chen,Yinying Lu et al.
Jun Lin et al.
BP001 is a promising small molecule compound that has been specifically designed to target and degrade Bruton's tyrosine kinases (BTK), which is known to play a crucial role in lymphoma development. Macrophages are important immune cells in...
The effect of bee drone brood on the motility and viability of stallion spermatozoa-an in vitro study [0.03%]
蜂王幼虫对公马精子运动性和活力的影响-一项体外研究
Michal Lenický,Ewelina Sidor,Lucia Dianová et al.
Michal Lenický et al.
Bee drone brood is a beehive by-product with high hormonal activity used in natural medicine to treat male infertility. The aim of the study was to assess the effect of drone brood on stallion spermatozoa during a short-term incubation for ...
Murf1 alters myosin replacement rates in cultured myotubes in a myosin isoform-dependent manner [0.03%]
Murf1以肌球蛋白异构体依赖的方式改变培养的肌管中肌球蛋白的替换速率
Emi Uenaka,Koichi Ojima,Takahiro Suzuki et al.
Emi Uenaka et al.
Skeletal muscle tissue increases or decreases its volume by synthesizing or degrading myofibrillar proteins. The ubiquitin-proteasome system plays a pivotal role during muscle atrophy, where muscle ring finger proteins (Murf) function as E3...
Cardiac differentiation of chimpanzee induced pluripotent stem cell lines with different subspecies backgrounds [0.03%]
具有不同亚种背景的黑猩猩诱导多能干细胞系的心脏分化能力
Mika Takahi,Yusuke Hamazaki,Kiyoshi Ohnuma et al.
Mika Takahi et al.
The comparative analysis between humans and non-human primates is an instrumental approach for elucidating the evolutional traits and disease propensity of humans. However, in primates, cross-species analyses of their developmental events h...
Bringing cell biology into classroom: tips to culture and observe skeletal muscle cells in high school and college [0.03%]
把细胞生物学带进教室：在高中和大学培养和观察骨骼肌细胞的建议
Ryoichi Matsuda,Fumiko Okiharu
Ryoichi Matsuda
Watching living cells through a microscope is much more exciting than seeing pictures of cells in high school and college textbooks. However, bringing cell cultures into the classroom is challenging for biology teachers since culturing cell...
Evaluating osteogenic potential of a 3D-printed bioceramic-based scaffold for critical-sized defect treatment: an in vivo and in vitro investigation [0.03%]
一种基于生物陶瓷的3D打印支架的促骨生长潜能评估：体内外研究
Hannaneh Safiaghdam,Sahar Baniameri,Hossein Aminianfar et al.
Hannaneh Safiaghdam et al.
The integration of precision medicine principles into bone tissue engineering has ignited a wave of research focused on customizing intricate scaffolds through advanced 3D printing techniques. Bioceramics, known for their exceptional biocom...
Eri Tsuboi,Yuki Asakawa,Naoto Hirose et al.
Eri Tsuboi et al.
Osteoblast-derived semaphorin3A (Sema3A) has been reported to be involved in bone protection, and Sema3A knockout mice have been reported to exhibit chondrodysplasia. From these reports, Sema3A is considered to be involved in chondrogenic d...