Spatiotemporal distribution of PTEN before directed cell migration in monolayers [0.03%]
单层细胞定向迁移前PTEN的时空分布规律
Quanzhi Lu,Saori Sasaki,Toshihiro Sera et al.
Quanzhi Lu et al.
The intracellular distribution of phosphatase and tensin homolog (PTEN) is closely related to directed cell migration. In single cells, PTEN accumulates at the rear of the cell before and during directed migration; however, the spatiotempor...
Cultivation of primary cells derived from three organs of a striped dolphin (Stenella coeruleoalba) using a simple culture method [0.03%]
一种简单的培养方法培养条纹海豚（Stenella coeruleoalba）三种器官原代细胞的研究
Kaede Tashiro,Takao Segawa,Miwa Suzuki et al.
Kaede Tashiro et al.
Cetacean-cultured cells are a promising tool for life science research. Most cells used in cetacean research are derived from the skin and kidneys. However, cell cultures from various organs are required for more flexible cetacean research....
Proinflammatory cytokines suppress stemness-related properties and expression of tight junction in canine intestinal organoids [0.03%]
促炎症细胞因子通过抑制犬小肠类器官干性相关属性及紧密连接蛋白表达增加其通透性
Meg Nakazawa,Itsuma Nagao,Yoko M Ambrosini
Meg Nakazawa
Recent advancements in canine intestinal organoid research have paved the way for the development of enhanced in vitro models, crucial for exploring intestinal physiology and diseases. Despite these strides, there is a notable gap in creati...
Transfection, cytotoxicity, and cell cycle studies on the two newly developed and characterized humpback grouper (Cromileptes altivelis) fin cell lines [0.03%]
两种新建立并鉴别的月氏鱼鳍细胞系的转染、毒性及细胞周期研究
Priyanka Poulose,K S Sobhana,Swathy Vijayan et al.
Priyanka Poulose et al.
The development and characterization of two novel humpback grouper (Cromileptes altivelis) fin cell lines are described in this study. The CA1F3Ex and CA1F4Tr cell lines were developed by explant and trypsinization methods, respectively, in...
A modified method for isolating sinoatrial node myocytes from adult mice [0.03%]
一种改良的分离成人鼠窦房结起搏细胞的方法
Qiang Li,Hanying Zhang,Ronghua Liu et al.
Qiang Li et al.
Sinoatrial node (SAN) is the pacemaker of the heart in charge of initiating spontaneous electronical activity and controlling heart rate. Myocytes from SAN can generate spontaneous rhythmic action potentials, which propagate through the myo...
Christelle Plaza,Christophe Capallere,Celine Meyrignac et al.
Christelle Plaza et al.
Since March 2013, animal testing for toxicity evaluation of cosmetic ingredients is banned in Europe. This directive applies to all personal care ingredients including oral ingredients. Gingival in vitro 3D models are commercially available...
Integrated bioinformatics and validation reveal PTGS2 and its related molecules to alleviate TNF-α-induced endothelial senescence [0.03%]
整合生物信息学和验证发现PTGS2及其相关分子可缓解TNF-α诱导的内皮细胞衰老
Hongjie Xu,He Wang,Xiaoping Ning et al.
Hongjie Xu et al.
Accumulative evidences have indicated the interaction between cellular senescence and ferroptosis. This study intends to investigate the ferroptosis-related molecular markers in TNF-α-induced endothelial senescence. The microarray expressi...
S100A11 is involved in the progression of colorectal cancer through the desmosome-catenin-TCF signaling pathway [0.03%]
S100A11通过粘合斑-猫眼素-TCF信号通路参与结直肠癌进展
Jin Zhou,Hitoshi Murata,Nahoko Tomonobu et al.
Jin Zhou et al.
Compiling evidence has indicated that S100A11 expression at high levels is closely associated with various cancer species. Consistent with the results reported elsewhere, we have also revealed that S100A11 is highly expressed in squamous ce...
MiR-483-3p promotes dental pulp stem cells osteogenic differentiation via the MAPK signaling pathway by targeting ARRB2 [0.03%]
microRNA-483-3p通过靶向ARRB2促进牙髓干细胞成骨分化 via MAPK信号通路
Xin Yu,Juan Ge,Huimin Xie et al.
Xin Yu et al.
Human dental pulp stem cells (DPSCs) have become an important component for bone tissue engineering and regenerative medicine due to their ability to differentiate into osteoblast precursors. Two miRNA chip datasets (GSE138180 and E-MTAB-30...
Effects of centrifugation treatment before electroporation on gene editing in pig embryos [0.03%]
离心处理对猪胚胎电转基因编辑效率的影响研究
Bin Liu,Manita Wittayarat,Koki Takebayashi et al.
Bin Liu et al.
Genetic mosaicism, characterized by multiple genotypes within an individual, is considered an obstacle to CRISPR/Cas9 genome editing in animal models. Despite the various strategies for minimizing mosaic mutations, no definitive methods exi...