Development and characterization of polyvinyl alcohol/gelatin/chitosan hydrogel for tissue engineering and wound healing applications using a fish cell line model [0.03%]
基于鱼细胞系模型用于组织工程和伤口愈合的聚乙烯醇/明胶/壳聚糖水凝胶的开发与表征
Sivaraj Mithra,Ali Asna Jabeen,Vinay Kumar et al.
Sivaraj Mithra et al.
Chitosan-based hydrogels have gained considerable attention in biomedical research due to their inherent biocompatibility, biodegradability, and non-toxicity. When combined with polyvinyl alcohol (PVA), the resulting hydrogels exhibit super...
NCF-1 plays a pivotal role in the survival of adenocarcinoma cells of pancreatic and gastric origins [0.03%]
NCF-1在胰腺和胃起源的腺癌细胞存活中发挥关键作用
Chiemi Furuya-Ikude,Akane Kitta,Naoko Tomonobu et al.
Chiemi Furuya-Ikude et al.
Reactive oxygen species (ROS) play a pivotal biological role in cells, with ROS function differing depending on cellular conditions and the extracellular environment. Notably, ROS act as cytotoxic factors to eliminate infectious pathogens o...
Correction: The adaptation of bovine embryonic stem cells to the changes of feeder layers [0.03%]
关于牛胚胎干细胞对饲养层变化的适应性的订正研究论文
Wenqiang Xu,Lingna Gao,Wei Li et al.
Wenqiang Xu et al.
MiR-146a-5p downregulated TRAF6/NF-κB p65 pathway to attenuate the injury of HT-22 cells induced by oxygen-glucose deprivation/reoxygenation [0.03%]
miR-146a-5p通过下调TRAF6/ NF-κB p65信号通路缓解氧糖剥夺再灌注HT-22细胞损伤
Yuan Deng,Ganlan Wang,Dan Hou et al.
Yuan Deng et al.
MicroRNA-146a-5p (miR-146a-5p) actively participates in the process of cerebral ischemia-reperfusion (CI/R) injury. Dysregulation of the tumor necrosis factor receptor-associated factor 6 (TRAF6)/nuclear factor kappa-B (NF-κB) p65 axis is ...
RO4929097 inhibits NICD3 to alleviate pulmonary hypertension via blocking Notch3/HIF-2α/FoxM1 signaling pathway [0.03%]
RO4929097通过阻断Notch3/HIF-2α/FoxM1信号通路抑制NICD3从而缓解肺动脉高压
Hao Zhu,Cheng Li,Fang Hu et al.
Hao Zhu et al.
Pulmonary hypertension (PH) is a condition in which the smooth muscle cells (SMCs) in the pulmonary arteries multiply excessively, causing the arteries to narrow. This can ultimately result in right heart failure and premature death. Notch3...
Enhanced design of pCMViR-TSC plasmid vector for sustainably high cargo gene expression in mammalian cells [0.03%]
一种改进的pCMViR-TSC质粒载体设计可持续高效表达哺乳动物细胞转基因蛋白质
Masakiyo Sakaguchi,Rie Kinoshita,Nahoko Tomonobu et al.
Masakiyo Sakaguchi et al.
The first-generation pCMViR-TSC, implemented through the promoter sandwich rule, yields 10- to 100-fold higher gene expression than the standard plasmid used with the CMV (cytomegalovirus) or CAG promoter. However, the vector's shortcomings...
Exosomal miR-590-3p derived from bone marrow mesenchymal stem cells promotes osteoblast differentiation and osteogenesis by targeting TGFBR1 [0.03%]
骨髓间充质干细胞衍生的外泌体miR-590-3p通过靶向TGFBR1促进成骨细胞分化和骨骼生成
Dandan Luo,Wantao Xie,Xiaoli He et al.
Dandan Luo et al.
Bone marrow mesenchymal stem cells (BMSCs) have been verified to be essential factors regulating osteogenic functions, which is mainly attributed to their secretion of extracellular vesicles. Exosomes derived from BMSCs (BMSCs-Exo) contribu...
Controlling spheroid attachment improves pancreatic beta cell differentiation from human iPS cells [0.03%]
控制类球体的附着性可提高从人类iPSCs中分化胰腺β细胞的质量
Ayumi Horikawa,Tatsuo Michiue
Ayumi Horikawa
Regenerative medicine using human induced pluripotent stem cells (hiPSCs) is available for treating type 1 diabetes; however, the efficiency and maturation of hiPSC differentiation into pancreatic beta cells requires improvement. Various pr...
Ginsenoside Re promotes proliferation of murine bone marrow mesenchymal stem cells in vitro through estrogen-like action: comment [0.03%]
人参皂苷Re通过类似雌激素的作用促进小鼠骨髓间充质干细胞的增殖：评述
Hinpetch Daungsupawong,Viroj Wiwanitkit
Hinpetch Daungsupawong
The inhibitory effect of salidroside on RANKL-induced osteoclast formation via NFκB suppression [0.03%]
通过抑制NF-κB介导的信号通路研究山柰酚茋对RANKL诱导破骨细胞形成的抑制作用
Adilsaikhan Mendjargal,Shijir Narmandakh,Munkhjargal Zinamyadar et al.
Adilsaikhan Mendjargal et al.
Bone fractures are a prevalent clinical issue, and recent studies highlighted the promising potential of natural bone healing agents in enhancing fracture repair and regeneration. The regulatory interaction mechanism between osteoblasts and...