Response of epithelial cell lines from the rainbow trout gut and gill to ammonia [0.03%]
氨对虹彩 trout 肠和鳃上皮细胞系的影响响应
Daylan T Pritchard,Caio J Nicholson de Figueiroa,Niels C Bols et al.
Daylan T Pritchard et al.
Rainbow trout epithelial cell lines from the gill, RTgill-W1, and gut, RTgutGC, were exposed to NH4Cl at 18-21 °C in L15 (basal medium) with fetal bovine serum and were found to undergo cytoplasmic vacuolization and cell death, depending o...
The impact of beauvericin on rainbow trout intestinal epithelial cells at different temperatures and dosing methods [0.03%]
贝奥弗里辛对虹鳟肠上皮细胞的影响受温度和给药方式的影响
Vivian R Dayeh,Anita Solhaug,Mark E Hamilton et al.
Vivian R Dayeh et al.
Mycotoxins in aquatic feeds and their effects on fish are becoming more important in aquaculture, as fishmeal and fish oil in feeds are being replaced with more sustainable plant protein. Here, we investigated the potential of the mycotoxin...
Ubiquitin-specific protease 7 exacerbates acute pancreatitis progression by enhancing ATF4-mediated autophagy [0.03%]
泛素特异性蛋白酶7通过增强ATF4介导的自噬促进急性胰腺炎进展
Feng Peng,Xiaofeng Deng
Feng Peng
Acute pancreatitis (AP) is a serious inflammatory disease with high incidence rate and mortality. It was confirmed that overactivation of autophagy in acinar cells can increase the risk of AP. Nevertheless, the regulatory mechanism of autop...
LINC01224 promotes the Warburg effect in gastric cancer by activating the miR-486-5p/PI3K axis [0.03%]
长链非编码RNA LINC01224通过激活miR-486-5p/PI3K轴促进胃癌的瓦博格效应
Yuling Bin,Minji Liu,Rong He et al.
Yuling Bin et al.
The Warburg effect, a common feature of solid tumors, rewires the metabolism and promotes growth, survival, proliferation, and long-term maintenance in gastric cancer (GC). We performed in vitro and in vivo studies of the pathogenesis of GC...
Impact and mechanism of the TBX-22 gene mutation G874A on the epithelial-mesenchymal transition in medial edge epithelial cells [0.03%]
TBX-22基因G874A突变对角膜内侧上皮细胞上皮间质转分化的影响及机制研究
Chen Xu,Yali Hou,Li Ma et al.
Chen Xu et al.
Cleft lip and palate (CL/P) are prevalent congenital anomalies with complex genetic causes. The G874A mutation of T-box transcription factor 22 (TBX-22) gene is notably associated with CL/P, while the underlying mechanism remains to be clar...
Adipose-derived stem cells regulate mitochondrial dynamics to alleviate the aging of HFF-1 cells [0.03%]
脂肪源性干细胞通过调控线粒体动态减轻人永生乳晕成纤维细胞的衰老现象
Qi Luo,Ling Liu
Qi Luo
The objective of this study is to explore how adipose-derived stem cells (ASCs) regulate mitochondrial structure and function and the impact of this regulation on slowing cellular senescence. HFF-1 cells were induced by H2O2 to establish a ...
Detection of Tilapia parvovirus in farm-reared tilapia in India and its isolation using fish cell lines [0.03%]
印度养殖场尼罗罗非鱼中华鳋病毒的检测及其鱼类细胞系的分离鉴定
Allahbagash Badhusha,Sivaraj Mithra,Gani Taju et al.
Allahbagash Badhusha et al.
Tilapia parvovirus (TiPV) is an emerging viral pathogen and responsible for severe economic loss in tilapia culture production. Lethargic, cutaneous haemorrhages; ocular lesions; discolouration of gill and cloudy eye and exophthalmia are co...
Melatonin inhibits ferroptosis through the ATF3/GPX4 signaling pathway to relieve myocardial ischemia-reperfusion injury in rats [0.03%]
褪黑素通过ATF3/GPX4信号通路抑制铁死亡以缓解大鼠心肌缺血再灌注损伤
Minjie He,Yongheng Yang,Xing He et al.
Minjie He et al.
Melatonin (MEL), functioning as a circulating hormone, is important for the regulation of ferroptosis in different health scenarios and acts as a crucial antioxidant in cardiovascular diseases. However, its specific function in ferroptosis ...
Tianxiangdan suppresses foam cell formation by enhancing lipophagy and reduces the progression of atherosclerosis [0.03%]
天香丹通过促进脂质自噬抑制泡沫细胞形成并减少动脉粥样硬化进展
Ya-Jie Zhang,Huan He,Guligena Sawuer et al.
Ya-Jie Zhang et al.
The aim of this study is to assess the impact of Tianxiangdan (TXD) on lipophagy in foam cells and its underlying mechanism in treating atherosclerosis, particularly focusing on its efficacy in lowering blood lipids. In vivo, ApoE-/- athero...
Urolithin B suppresses phenotypic switch in vascular smooth muscle cells induced by PDGF-BB via inhibiting the PI3K-AKT pathway [0.03%]
尿石素B通过抑制PI3K-AKT途径抑制PDGF-BB诱导的血管平滑肌细胞表型转换
Shengbiao Li,Yi Zhang,Tianyi Zhang et al.
Shengbiao Li et al.
Atherosclerosis (AS) is a prevalent cardiovascular condition, and the growth and phenotypic switch of vascular smooth muscle cells (VSMCs) play a crucial role in its development. Studies have revealed that the activation of certain transcri...