Kristin Watson,Brian D Watson,Karen S Pater
Kristin Watson
Background: Peripheral arterial disease (PAD) is a progressive atherosclerotic condition affecting approximately 27 million people in North America and Europe. Albeit a common clinical malady, it is underrecognized and un...
Rehan Aziz,Boris Lorberg,Rajesh R Tampi
Rehan Aziz
Background: Bipolar affective disorder is not uncommon in the elderly; prevalence rates in the United States range from 0.1% to 0.4%. However, it accounts for 10% to 25% of all geriatric patients with mood disorders and 5...
Rasagiline (TVP-1012): a new selective monoamine oxidase inhibitor for Parkinson's disease [0.03%]
治疗帕金森氏病的新单胺氧化酶抑制剂盐酸拉沙吉兰(TVP-1012)
David R P Guay
David R P Guay
Objective: This article reviews the chemistry, pharmacodynamics, pharmacokinetics, clinical efficacy, tolerability, drug-interaction potential, indications, dosing, and potential role of rasagiline mesylate, a new selecti...
Hydrochlorothiazide-induced angioedema in a patient allergic to sulfonamide antibiotics: evidence from a case report and a review of the literature [0.03%]
氢氯噻嗪致血管性水肿一例及文献复习（磺胺类药物过敏患者）
J Mark Ruscin,Robert L Page nd,John Scott
J Mark Ruscin
Background: Hypersensitivity reactions in patients receiving sulfonamide antibiotics have been frequently documented in the literature, but cross-reactivity with sulfonamide non-antibiotics rarely has been reported. ...
Patricia Sawyer,Eric V Bodner,Christine S Ritchie et al.
Patricia Sawyer et al.
Background: Pain is a common symptom and significant problem for older adults; up to one half of community-dwelling older adults have pain that interferes with normal function. ...
Association of age with analgesic use for back and joint disorders in outpatient settings [0.03%]
年龄与门诊腰背及关节疾病镇痛药使用情况的关系分析
Alex D Federman,Ann Litke,R Sean Morrison
Alex D Federman
Background: Pain is a common, troubling symptom of various disorders, chronically affecting up to 11% of adults in the general public. Despite a growing emphasis on improving the quality of pain management and the increas...
The risk of adverse drug events and hospital-related morbidity and mortality among older adults with potentially inappropriate medication use [0.03%]
不适当用药的老年人发生药物不良事件及相关住院危害的风险评估
Robert L Page nd,J Mark Ruscin
Robert L Page nd
Background: Inappropriate medication prescribing is a significant problem among older adults that may contribute to increased morbidity and mortality as well as increased costs of care. The development of specific lists o...
Recommendations for best practices in the treatment of Alzheimer's disease in managed care [0.03%]
关于保健管理中治疗阿尔茨海默病的最佳实践建议
Howard M Fillit,Rachelle Smith Doody,Kimberly Binaso et al.
Howard M Fillit et al.
Background: Alzheimer's disease and related dementias (ADRDs) are increasingly recognized as important causes of impaired cognition, function, and quality of life, as well as excess medical care utilization and costs in t...
Efficacy and tolerability of solifenacin in elderly subjects with overactive bladder syndrome: A pooled analysis [0.03%]
索利那新治疗老年女性膀胱过度活动症患者的有效性和耐受性：合并分析结果
Paul J Drinka
Paul J Drinka
Sex influences on cholinesterase inhibitor treatment in elderly individuals with Alzheimer's disease [0.03%]
性别对老年阿尔茨海默病患者乙酰胆碱酯酶抑制剂治疗的影响
Wendy M Haywood,Elizabeta B Mukaetova-Ladinska
Wendy M Haywood
Background: The second generation of cholinesterase inhibitors (ChEIs) is approved in the United Kingdom for the treatment of mild to moderate Alzheimer's disease (AD). The UK National Institute of Clinical Excellence has...