Self-reported efficacy and tolerability of ramelteon 8 mg in older adults experiencing severe sleep-onset difficulty [0.03%]
老年睡眠 onset困难患者服用雷美替隆8毫克的自我疗效及耐受性报告
Louis J Mini,Sherry Wang-Weigand,Jeff Zhang
Louis J Mini
Background: Ramelteon is a selective MT(1)/MT(2) melatonin receptor agonist indicated for the treatment of insomnia characterized by difficulty with sleep onset. ...
Randomized Controlled Trial
The American journal of geriatric pharmacotherapy. 2007 Sep;5(3):177-84. DOI:10.1016/j.amjopharm.2007.09.004 2007
Neal Hermanowicz
Neal Hermanowicz
Dextromethorphan-induced near-fatal suicide attempt in a slow metabolizer at cytochrome P450 2D6 [0.03%]
细胞色素P450 2D6慢代谢所致的右美沙芬自杀企图致险症病例报告
Nadia Matin,Amit Kurani,Cheryl A Kennedy et al.
Nadia Matin et al.
Background: Dextromethorphan (DXM) is a common ingredient in several prescriptions and over-the-counter cough preparations. Its metabolism in humans includes hepatic O- and N-demethylation to form dextrorphan and 3-methox...
Arlene S Bierman,Mary Jo V Pugh,Irfan Dhalla et al.
Arlene S Bierman et al.
Background: Previous studies have suggested that older women may be more likely than older men to receive potentially inappropriate prescriptions. A better understanding of sex differences in inappropriate prescribing can...
A retrospective study of the association between megestrol acetate administration and mortality among nursing home residents with clinically significant weight loss [0.03%]
回顾性研究护理机构中临床显著体重减轻的居民使用甲地孕酮与死亡率之间的关联
Donald Bodenner,Trey Spencer,Ann T Riggs et al.
Donald Bodenner et al.
Background: Megestrol acetate (MA) is a progestin widely used to treat weight loss and cachexia in patients suffering from AIDS or cancer. Although MA is also frequently prescribed for similarly malnourished elderly indiv...
Prophylaxis for opioid-induced constipation in elderly long-term care residents: a cross-sectional study of Medicare beneficiaries [0.03%]
阿片类药物引起的老年长期护理居民的便秘预防措施：一项针对医疗保险受益人的横截面研究
Ellina K Max,Jose J Hernandez,Deborah A Sturpe et al.
Ellina K Max et al.
Background: Opioid analgesics are effective therapeutic agents for malignant and nonmalignant pain, but their use is often compromised by unwanted adverse effects on the central nervous system and gastrointestinal (GI) tr...
Use of wet nebulized inhaled respiratory medications under criteria-based reimbursement guidelines in a publicly funded Seniors' Pharmacare Program in Nova Scotia, Canada [0.03%]
加拿大新斯科舍省公共资助的老年人药物福利计划中基于标准的报销指南下的湿化吸入呼吸用药的使用情况
Susan K Bowles,Ingrid Sketris,George Kephart;Drug Evaluation Alliance of Nova Scotia
Susan K Bowles
Background: During the 1999/2000 fiscal year, approximately 19% of beneficiaries in the Nova Scotia Seniors' Pharmacare Program (NSSPP), a publicly funded drug insurance program in Nova Scotia, Canada, received inhaled re...
Assessment of tolerability in elderly patients: changing to lamotrigine therapy [0.03%]
老年患者耐受性评价：换用拉莫三嗪治疗评估
Bradley K Evans,Robert P Kustra,Anne E Hammer
Bradley K Evans
Background: Of all age groups, adults older than 75 years have the highest risk of seizures, especially partial seizures. In the past, physicians commonly used phenytoin, carbamazepine, and valproic acid as antiepileptic ...
Medication adherence and health care costs with the introduction of latanoprost therapy for glaucoma in a Medicare managed care population [0.03%]
医保管理保健人群中引入拉坦前列腺素治疗对青光眼患者的药物依从性及医疗成本的影响
Monali J Bhosle,Gregory Reardon,Fabian T Camacho et al.
Monali J Bhosle et al.
Background: Latanoprost, a prostaglandin inhibitor, is increasingly being used in the therapeutic management of glaucoma. However, there is scant literature examining the cost and outcome ramifications of latanoprost. ...
Predictors of long-acting opioid use and oral versus transdermal route among older Medicaid beneficiaries [0.03%]
长期使用长效阿片类药物及其给药途径的预测因子：医疗保险受益者的队列研究
Sally K Rigler,Theresa I Shireman,Lynne Kallenbach
Sally K Rigler
Background: The availability of long-acting (LA) opioid medications represents an advance in the treatment of persistent pain, raising the question of what factors predict receipt of this newer treatment approach. ...