Emily R Hajjar,Joseph T Hanlon,Margaret B Artz et al.
Emily R Hajjar et al.
Background: Adverse drug reactions (ADRs) are common in older (age >or=65 years) outpatients (prevalence, 5%-35%), but there is no consensus on factors that put these patients at high risk for ADRs. Identifying a uniform ...
Medication-related predictors of health-related quality of life in glaucoma patients enrolled in a medicare health maintenance organization [0.03%]
医疗保险组织中青光眼患者的与药物相关的健康相关生活质量预测指标
Rajesh Balkrishnan,J Brent Bond,Wesley G Byerly et al.
Rajesh Balkrishnan et al.
Background: Glaucoma is an important public health concern in the United States, particularly among older adults (aged >or=65 years). Pharmacologic therapy for glaucoma consists mainly of topical eye drops containing beta...
Trends in the prescription of inappropriate drugs for the elderly between 1995 and 1999 [0.03%]
1995年至1999年期间不合理用药处方的变化趋势——针对老年人用药
Bruce Stuart,Sachin Kamal-Bahl,Becky Briesacher et al.
Bruce Stuart et al.
Background: Using criteria developed by Beers et al between 1991 and 1997, previous studies have reported high levels of inappropriate drug prescribing for community-dwelling elderly patients (age>or=65 years). However, i...
Use of resources and cost implications of stroke prophylaxis with warfarin for patients with nonvalvular atrial fibrillation [0.03%]
华法林抗凝预防非瓣膜性房颤患者脑卒中的资源使用和费用分析
Ahmed H Abdelhafiz,Nigel M Wheeldon
Ahmed H Abdelhafiz
Background: Patients with nonvalvular atrial fibrillation (NVAF) have often been excluded from long-term anticoagulant trials, and therefore patients in clinical practice may have different risk, compliance, and safety co...
Joseph T Hanlon,Catherine I Lindblad,Emily R Hajjar et al.
Joseph T Hanlon et al.
Background: Although pharmacotherapy for the elderly can treat diseases and improve well-being, its benefits can be compromised by drug-related problems. ...
Oxcarbazepine, topiramate, zonisamide, and levetiracetam: potential use in neuropathic pain [0.03%]
奥卡西平、托吡酯、佐尼沙胺和利莫昔泮在神经痛治疗中的潜在应用价值
David R P Guay
David R P Guay
Background: Oxcarbazepine, topiramate, zonisamide, and levetiracetam are the antiepileptic drugs (AEDs) most recently approved by the US Food and Drug Administration. Based on the experience with carbamazepine, gabapentin...
Christine M Ruby,Gerda G Fillenbaum,Maragatha N Kuchibhatla et al.
Christine M Ruby et al.
Background: Constipation, a common and sometimes severe problem in the elderly, is often treated with laxatives. Objective: The purpose...
Is antioxidant use protective of cognitive function in the community-dwelling elderly? [0.03%]
抗氧化剂的使用是否有利于维持社区中老年人的认知功能？
Shelly L Gray,Joseph T Hanlon,Lawrence R Landerman et al.
Shelly L Gray et al.
Background: The role of oxidative stress in the pathogenesis of diseases such as macular degeneration, certain types of cancer, and Alzheimer's disease has received much attention. Thus, there is considerable interest in ...