Drug development for Alzheimer's disease: where are we now and where are we headed? [0.03%]
阿茨海默氏症药物研发进展及未来方向展望
Marwan N Sabbagh
Marwan N Sabbagh
Objective: The aim of this article was to provide a survey of the clinical development of pharmacotherapy for Alzheimer's disease (AD). Methods: ...
Anticoagulation for stroke prevention in elderly patients with atrial fibrillation, including those with falls and/or early-stage dementia: a single-center, retrospective, observational study [0.03%]
抗凝药物用于老年房颤患者卒中预防的队列研究，包括有摔倒或轻度痴呆患者：一项单中心回顾性观察研究
Laurie G Jacobs,Henny H Billett,Katherine Freeman et al.
Laurie G Jacobs et al.
Background: Anticoagulation for stroke prevention is underused in elderly patients with nonvalvular atrial fibrillation (AF). Those with falls and/or early dementia may be at particular risk for stroke and hemorrhage. ...
Polypharmacy in hospitalized older adult cancer patients: experience from a prospective, observational study of an oncology-acute care for elders unit [0.03%]
老年肿瘤住院患者的多重用药：来自肿瘤-Acute Care For Elders病房前瞻性观察研究的体会
Kellie L Flood,Maria B Carroll,Cyndi V Le et al.
Kellie L Flood et al.
Background: A novel Oncology-Acute Care for Elders (OACE) unit that uses an interdisciplinary team to enhance recognition and management of geriatric syndromes in hospitalized older adult cancer patients has been establis...
Results of a longitudinal analysis of national data to examine relationships between organizational and market characteristics and changes in antipsychotic prescribing in US nursing homes from 1996 through 2006 [0.03%]
基于国家数据的长期分析结果：探讨组织与市场特征与美国老年护理机构抗精神病处方变化关系(1996-2006)
Nicholas G Castle,Joseph T Hanlon,Steven M Handler
Nicholas G Castle
Objective: The aim of this work was to examine the association between organizational characteristics, market characteristics, and changes in antipsychotic medication use in US nursing homes over time. ...
Awareness of pharmaceutical cost-assistance programs among inner-city seniors [0.03%]
认识城市老人药品经济援助项目的意识
Alex D Federman,Dana Gelb Safran,Salomeh Keyhani et al.
Alex D Federman et al.
Background: Lack of awareness may be a significant barrier to participation by low- and middle-income seniors in pharmaceutical cost-assistance programs. ...
Whom do older adults trust most to provide information about prescription drugs? [0.03%]
老年人最信任谁来提供有关处方药的信息？
Julie M Donohue,Haiden A Huskamp,Ira B Wilson et al.
Julie M Donohue et al.
Background: Cost-related nonadherence to medieations is common among older adults, yet physician-patient communication about medication cost concerns is infrequent. One factor affecting communication and adherence may be ...
Discrepancies in reported drug use in geriatric outpatients: relevance to adverse events and drug-drug interactions [0.03%]
老年门诊病人服药报告中的不一致情况及其与不良事件和药物相互作用的关系
Linda R Tulner,Ingeborg M J A Kuper,Suzanne V Frankfort et al.
Linda R Tulner et al.
Background: Increased age is associated with polypharmacy. Polypharmacy is a risk factor for severe adverse drug reactions (ADRs) and is associated with an increased risk of mortality. ...
Potentially inappropriate medication prescribing in outpatient practices: prevalence and patient characteristics based on electronic health records [0.03%]
基于电子健康记录的门诊不适当处方及其患者特征分析
Michael D Buck,Ashish Atreja,Cherie P Brunker et al.
Michael D Buck et al.
Background: Some older adults receive potentially inappropriate medications (PIMs), increasing their risk for adverse events. A literature search did not find any US multicenter studies that measured the prevalence of PIM...
Effect of discontinuing cholinesterase inhibitor therapy on behavioral and mood symptoms in nursing home patients with dementia [0.03%]
停用胆碱酯酶抑制剂治疗对痴呆症疗养院患者的行为和情绪症状的影响
Lori A Daiello,Brian R Ott,Kate L Lapane et al.
Lori A Daiello et al.
Background: Cholinesterase inhibitors (CHEIs) ameliorate some types of behavioral symptoms in patients with Alzheimer's disease. However, there has been little previous study of the outcomes associated with discontinuing ...
Self-reported prevalence and factors associated with nonadherence with glaucoma medications in veteran outpatients [0.03%]
退伍军人门诊患者自报的青光眼药物非依从性患病率及影响因素
Betsy Sleath,Rex Ballinger,David Covert et al.
Betsy Sleath et al.
Objective: The purpose of the current study was to determine the self-reported prevalence of and factors associated with nonadherence with glaucoma medications in veteran outpatients. ...