Microcomputed tomography imaging of skeletal development and growth [0.03%]
微观计算机断层扫描在骨骼发育和生长方面的应用研究进展
Robert E Guldberg,Angela S P Lin,Rhima Coleman et al.
Robert E Guldberg et al.
Skeletogenesis is an exquisitely orchestrated and dynamic process, culminating in the formation of highly variable and complex mineralized structures that are optimized for their function. While cellular and molecular biology studies have p...
Molecular imaging of the embryonic heart: Fables and facts on 3D imaging of gene expression patterns [0.03%]
胚胎心脏的分子影像：基因表达模式三维成像的寓言与事实
Jan M Ruijter,Alexandre T Soufan,Jaco Hagoort et al.
Jan M Ruijter et al.
Molecular imaging, which is the three-dimensional (3D) visualization of gene expression patterns, is indispensable for the study of the function of genes in cardiac development. The instrumentation, as well as the development of specific co...
Making the mouse embryo transparent: identifying developmental malformations using magnetic resonance imaging [0.03%]
使小鼠胚胎透明：使用磁共振成像识别发育畸形
Jürgen E Schneider,Shoumo Bhattacharya
Jürgen E Schneider
Developmental malformations are a major cause of childhood mortality and are typically characterized by lesions that allow survival of the embryo through gestation. The genetics of developmental malformations are powerfully studied by using...
Paul M Kulesa
Paul M Kulesa
The study of embryonic events using different animal model systems is crucial for gaining insights into human development and birth defects. Biological imaging plays a major role in this effort by providing a spatiotemporal framework to lin...
Jay R Hove
Jay R Hove
Flow-structure interactions are ubiquitous in nature, and are important factors in the proper development of form and function in living organisms. In order to uncover the mechanisms by which flow-structure interactions affect vertebrate de...
Dynamic imaging of cell, extracellular matrix, and tissue movements during avian vertebral axis patterning [0.03%]
鸟类脊椎轴图案化过程中细胞、细胞外基质和组织运动的动态影像学研究
Michael B Filla,András Czirók,Evan A Zamir et al.
Michael B Filla et al.
Vertebrate axis patterning depends on cell and extracellular matrix (ECM) repositioning and proper cell-ECM interactions. However, there are few in vivo data addressing how large-scale tissue deformations are coordinated with the motion of ...
Isabelle Miletich,Paul T Sharpe
Isabelle Miletich
The cranial neural crest cells, which are specialized cells of neural origin, are central to the process of mammalian tooth development. They are the only source of mesenchyme able to sustain tooth development, and give rise not only to mos...
Understanding endothelin-1 function during craniofacial development in the mouse and zebrafish [0.03%]
了解内皮素1在小鼠和斑马鱼颅面发育中的功能
David E Clouthier,Thomas F Schilling
David E Clouthier
Morphogenesis of the face and neck is driven by an intricate relay of signaling molecules and transcription factors organized into hierarchical pathways. The coordinated action of these pathways regulates the development of neural crest cel...
The neural crest: basic biology and clinical relationships in the craniofacial and enteric nervous systems [0.03%]
神经嵴：头面部和肠神经系统的基本生物学与临床关系
Peter G Farlie,Sonja J McKeown,Donald F Newgreen
Peter G Farlie
The highly migratory, mesenchymal neural crest cell population was discovered over 100 years ago. Proposals of these cells' origin within the neuroepithelium, and of the tissues they gave rise to, initiated decades-long heated debates, sinc...
Maya Sieber-Blum,Milos Grim
Maya Sieber-Blum
This review focuses on the recent identification of two novel neural crest-derived cells in the adult mammalian hair follicle, pluripotent stem cells, and Merkel cells. Wnt1-cre/R26R compound transgenic mice, which in the periphery express ...