Combinatorial transcriptional interaction within the cardiac neural crest: a pair of HANDs in heart formation [0.03%]
心脏神经嵴内的转录互作组合：心形成中的HAND对
Anthony B Firulli,Simon J Conway
Anthony B Firulli
The cardiac neural crest cells migrate from the rostral dorsal neural folds and populate the branchial arches, which contribute directly to the cardiac-outflow structures. Although neural crest cell specification is associated with a number...
Cell surface molecules and truncal neural crest ontogeny: a perspective [0.03%]
细胞表面分子与干祖级神经嵴的发育：一种观点
Robert Moore,Lionel Larue
Robert Moore
The neural crest cell is synonymous with vertebrates and can be viewed as a transitory, mobile vector that conveys neuroepithelial stem cells to a diverse number of remote locations in the embryo. Neural crest cells have been studied intens...
A slug, a fox, a pair of sox: transcriptional responses to neural crest inducing signals [0.03%]
Slug、狐狸和一双袜子：神经嵴诱导信号的转录反应
Elizabeth Heeg-Truesdell,Carole LaBonne
Elizabeth Heeg-Truesdell
The neural crest, a cell type found only in vertebrate embryos, gives rise to the structures of the skull and face and most of the peripheral nervous system, as well as other cell types characteristic of vertebrates. These cells are of grea...
Martín L Basch,Martín I García-Castro,Marianne Bronner-Fraser
Martín L Basch
The neural crest is an embryonic cell population that originates at the border between the neural plate and the prospective epidermis. Around the time of neural tube closure, neural crest cells emigrate from the neural tube, migrate along d...
Andrew P Spicer,Janet Y L Tien
Andrew P Spicer
In the past decade, there has been an explosion of interest in hyaluronan, an often misunderstood, biochemically simple, yet functionally complex carbohydrate polymer that is a resident of many extracellular matrices. Previously thought of ...
Heparan sulfate proteoglycans: coordinators of multiple signaling pathways during chondrogenesis [0.03%]
硫酸肝素蛋白多糖在软骨发生过程中的多重信号转导作用
Catherine B Kirn-Safran,Ronald R Gomes,Anissa J Brown et al.
Catherine B Kirn-Safran et al.
Heparan sulfate proteoglycans are abundantly expressed in the pericellular matrix of both developing and mature cartilage. Increasing evidence indicates that the action of numerous chondroregulatory molecules depends on these proteoglycans....
Regulation of protein diversity by alternative pre-mRNA splicing with specific focus on chondrogenesis [0.03%]
选择性拼接调节蛋白多样性及其在软骨发生中的作用
Audrey McAlinden,Necat Havlioglu,Linda J Sandell
Audrey McAlinden
Analysis of the human genome has dramatically demonstrated that the majority of protein diversity is generated by alternative splicing of pre-mRNA. This powerful and versatile mechanism controls the synthesis of functionally different prote...
Fine tuning of growth factor signals depends on fibrillin microfibril networks [0.03%]
生长因子信号的微调依赖于弹力纤维素微丝网状体系
Noe L Charbonneau,Robert N Ono,Glen M Corson et al.
Noe L Charbonneau et al.
Growth factors, potent regulators of cell differentiation, tissue morphogenesis, tissue homeostasis, and cellular response to injury, reside in the extracellular matrix. Genetic evidence in humans and mice as well as biochemical data implic...
Mon-Li Chu,Takeshi Tsuda
Mon-Li Chu
Fibulins are a family of five extracellular glycoproteins found in a variety of tissues in association with diverse supramolecular structures, including elastic fibers, basement membrane networks, fibronectin microfibrils, and proteoglycan ...
The role of ECM molecules in activity-dependent synaptic development and plasticity [0.03%]
细胞外基质分子在活动依赖性突触发育和可塑性中的作用
Ivan Pavlov,Sari Lauri,Tomi Taira et al.
Ivan Pavlov et al.
Growth and guidance of neurites (axons and dendrites) during development is the prerequisite for the establishment of functional neural networks in the adult organism. In the adult, mechanisms similar to those used during development may re...