Maria Seron-Ferre,Gullermo J Valenzuela,Claudia Torres-Farfan
Maria Seron-Ferre
Circadian rhythmicity is a fundamental characteristic of organisms, which helps ensure that vital functions occur in an appropriate and precise temporal sequence and in accordance with cyclic environmental changes. Living beings are endowed...
Marco De Santis,Elena Cesari,E Nobili et al.
Marco De Santis et al.
It has been widely reported that prenatal exposure to ionizing radiation can interfere with embryonic and fetal development, depending on dose and gestational age in which exposure occurs. According to several studies on animal models, diff...
Robert D Barrett,Laura Bennet,Joanne Davidson et al.
Robert D Barrett et al.
Preterm infants have a high rate of neurodevelopmental handicap. Recent imaging studies have revealed that adverse outcomes are strongly associated with reduced brain growth and neural complexity in later life. Increasing data suggest that ...
Lei Wang,Kent E Pinkerton
Lei Wang
Numerical research on the health effects of air pollution has been published in the last decade. Epidemiological studies have shown that children's exposure to air pollutants during fetal development and early postnatal life is associated w...
William S Webster,Dominique Abela
William S Webster
There is increasing evidence that the oxygen supply to the human embryo in the first trimester is tightly controlled, suggesting that too much oxygen may interfere with development. The use of hypoxia probes in mammalian embryos during the ...
Folate-mediated one-carbon metabolism and neural tube defects: balancing genome synthesis and gene expression [0.03%]
叶酸介导的一碳代谢与神经管缺陷：在基因组合成和基因表达间保持平衡
Anna E Beaudin,Patrick J Stover
Anna E Beaudin
Neural tube defects (NTDs) refer to a cluster of neurodevelopmental conditions associated with failure of neural tube closure during embryonic development. Worldwide prevalence of NTDs ranges from approximately 0.5 to 60 per 10,000 births, ...
Fetal thermal dose considerations during the obstetrician's watch: Implications for the pediatrician's observations [0.03%]
产科监护期间胎儿热剂量的考虑：对儿科观察的影响
Morton W Miller,Charles C Church,Richard K Miller et al.
Morton W Miller et al.
There are a number of seemingly "usual" thermal episodes during pregnancy for which it is relatively easy to determine a rudimentary aspect of thermal dose; these episodes include fever, labor, labor plus epidural, and the normally-occurrin...
Phyllis A Dennery
Phyllis A Dennery
Oxygen radicals, or reactive oxygen species (ROS) act as primary or secondary messengers to promote cell growth or death. Many instances demonstrate an important direct role of ROS in development because redox status regulates key transcrip...
The vertebrate segmentation clock and its role in skeletal birth defects [0.03%]
脊椎动物的体节时钟及其在骨骼出生缺陷中的作用
Emily T Shifley,Susan E Cole
Emily T Shifley
The segmental structure of the vertebrate body plan is most evident in the axial skeleton. The regulated generation of somites, a process called somitogenesis, underlies the vertebrate body plan and is crucial for proper skeletal developmen...
Genetic analysis of molecular oscillators in mammalian somitogenesis: clues for studies of human vertebral disorders [0.03%]
哺乳动物脊索发生过程中分子振荡器的遗传分析：研究人类椎骨疾病的线索
William Sewell,Kenro Kusumi
William Sewell
The repeating pattern of the human vertebral column is shaped early in development, by a process called somitogenesis. In this embryonic process, pairs of mesodermal segments called somites are serially laid down along the developing neural...