DNA adducts in human placenta exposed to ambient environment and passive cigarette smoke during pregnancy [0.03%]
孕期长期接触大气污染和被动吸烟对胎盘DNA的影响
Mrinal K Sanyal,Derya Mercan,Kathleen Belanger et al.
Mrinal K Sanyal et al.
Background: The risk of human diseases and abnormal development under the relatively reduced toxic environmental exposure conditions of passive cigarette smoke and urban pollution is emerging as significant. To assess the...
Cardiovascular abnormalities in Folr1 knockout mice and folate rescue [0.03%]
叶酸修复Folr1基因敲除小鼠心血管异常表型的研究
Huiping Zhu,Bogdan J Wlodarczyk,Melissa Scott et al.
Huiping Zhu et al.
Background: Periconceptional folic acid supplementation is widely believed to aid in the prevention of neural tube defects (NTDs), orofacial clefts, and congenital heart defects. Folate-binding proteins or receptors serve...
Evaluation of the General Practice Research Database congenital heart defects prevalence: comparison to United Kingdom national systems [0.03%]
英国一般医学诊疗研究数据库中先天性心脏病患病率的评价：与英国国家登记系统的比较
Keele E Wurst,Sara A Ephross,James Loehr et al.
Keele E Wurst et al.
Background: As part of an effort to validate the General Practice Research Database (GPRD) for future studies of medication use in pregnancy, this study examined whether the rates of all, and specific types of, congenital...
Placental growth patterns affect birth weight for given placental weight [0.03%]
胎盘生长模式影响给定胎盘重量下的出生体重
Carolyn M Salafia,Jun Zhang,Richard K Miller et al.
Carolyn M Salafia et al.
Background: An important contributor to fetal growth is growth of the placenta, the fetus' sole source of nutrients and oxygen. Here we use placental growth measures (larger and smaller disk diameters, reflecting the late...
Adolfo Correa,Janet D Cragan,James E Kucik et al.
Adolfo Correa et al.
Maternal flu or fever, medication use, and neural tube defects: a population-based case-control study in Northern China [0.03%]
中国北方基于人群的病例对照研究：母体患流感或发烧及用药与神经管缺陷的关系
Zhiwen Li,Aiguo Ren,Jianmeng Liu et al.
Zhiwen Li et al.
Background: Maternal exposure to flu or fever has been associated with increased risk for neural tube defects (NTDs); however, few studies have considered the effects of medications on the effects of flu or fever. We eval...
Maternal use of selective serotonin re-uptake inhibitors in early pregnancy and infant congenital malformations [0.03%]
早孕期使用选择性5-羟色胺再摄取抑制剂与婴儿先天畸形的关系
Bengt A J Källén,Petra Otterblad Olausson
Bengt A J Källén
Background: Maternal use of selective serotonin re-uptake inhibitors (SSRIs) has recently been associated with an increased risk for certain malformations. ...
Yanping Wang,Julia Barthold,Peter A Kanetsky et al.
Yanping Wang et al.
Background: Cryptorchidism is one of the most common congenital anomalies and is associated with increased risk for infertility and testicular cancer later in life. Findings from animal models and small clinical studies s...
Karyotypic changes detected by comparative genomic hybridization in a stillborn infant with chorioangioma and liver hemangioma [0.03%]
比较基因组杂交技术检测胎盘血管瘤和肝脏海绵状血管瘤死婴的染色体变化
Dimosthenis Miliaras,Jeffrey Conroy,Stavroula Pervana et al.
Dimosthenis Miliaras et al.
Background: Placental hemangioma (chorioangioma) and congenital hemangioma are relatively common tumors, which on rare occasions may occur together. Very little is known about the pathogenetic mechanisms underlying these ...
Patterns of severe abdominal wall defects: insights into pathogenesis, delineation, and nomenclature [0.03%]
严重腹壁缺陷的发病机制、分类和命名的新见解
Liliana Vauthay,Nancy Mazzitelli,Monica Rittler
Liliana Vauthay
Background: During the last decade, descriptions of malformation complexes involving an abdominal wall defect (AWD) have repeatedly appeared in the literature, and there has been frequent confusion regarding nomenclature,...