The More Things Change, the More They Stay the Same: Understanding the Safety of Outpatient Care [0.03%]
变亦不变：了解门诊医疗的安全性
Urmimala Sarkar
Urmimala Sarkar
The Safety of Outpatient Health Care : Review of Electronic Health Records [0.03%]
门诊医疗的安全性：电子健康档案的回顾
David M Levine,Ania Syrowatka,Hojjat Salmasian et al.
David M Levine et al.
Background: Despite considerable emphasis on delivering safe care, substantial patient harm occurs. Although most care occurs in the outpatient setting, knowledge of outpatient adverse events (AEs) remains limited. ...
Multicenter Study
Annals of internal medicine. 2024 Jun;177(6):738-748. DOI:10.7326/M23-2063 2024
In patients with type 2 diabetes and recent MI, colchicine reduced a composite CV outcome at 23 mo [0.03%]
在近期发生过心肌梗死的2型糖尿病患者中，秋水仙碱可降低23个月时的主要心血管不良事件复合终点的风险
Eric R Bates
Eric R Bates
Roubille F, Bouabdallaoui N, Kouz S, et al. Low-dose colchicine in patients with type 2 diabetes and recent myocardial infarction in the COLchicine Cardiovascular Outcomes Trial (COLCOT). Diabetes Care. 2024;47:467-470. 38181203.
Randomized Controlled Trial
Annals of internal medicine. 2024 May;177(5):JC54. DOI:10.7326/J24-0026 2024
Update Alert: Effectiveness and Safety of Treatments to Prevent Fractures in People With Low Bone Mass or Primary Osteoporosis: A Living Systematic Review and Network Meta-analysis for the American College of Physicians [0.03%]
更新 alert：治疗低骨量或原发性骨质疏松症患者骨折预防的疗效和安全性：美国内科医师学院动态系统评价和网状 meta 分析
Chelsea Ayers,Rachel Ward,Devan Kansagara
Chelsea Ayers
Meta-Analysis
Annals of internal medicine. 2024 Jun;177(6):eL230118. DOI:10.7326/L24-0118 2024
In HFpEF with obesity, semaglutide improved health status and weight loss at 52 wk, regardless of initial health status [0.03%]
在肥胖合并射血分数保留型心力衰竭患者中，索马鲁肽治疗可改善健康状况和促进体重减轻（为期52周），且与初始健康状况无关
Darren Lau
Darren Lau
Kosiborod MN, Verma S, Borlaug BA, et al; STEP-HFpEF Trial Committees and Investigators. Effects of semaglutide on symptoms, function, and quality of life in patients with heart failure with preserved ejection fraction and obesity: a prespe...
Randomized Controlled Trial
Annals of internal medicine. 2024 May;177(5):JC56. DOI:10.7326/J24-0025 2024
In older patients with AF and frailty, switching from VKA to NOAC therapy increased a composite of major or CRNM bleeding at 12 mo [0.03%]
在老年房颤且衰弱患者中，从维生素K拮抗剂转换为新型口服抗凝药增加主要或临床相关非大出血的复合终点事件（12个月）
Andrew Dunn
Andrew Dunn
Joosten LP, van Doorn S, van de Ven PM, et al. Safety of switching from a vitamin K antagonist to a non-vitamin K antagonist oral anticoagulant in frail older patients with atrial fibrillation: results of the FRAIL-AF randomized controlled ...
Randomized Controlled Trial
Annals of internal medicine. 2024 May;177(5):JC57. DOI:10.7326/J24-0024 2024
In AF, CHA2DS2-VASc 1 subgroups did not differ for predicting risk for arterial thromboembolism at 1 y [0.03%]
在AF中，CHA2DS2-VASc 1亚组无法用于预测一年内动脉性血栓栓塞风险
Luciano A Sposato,Michael D Hill
Luciano A Sposato
Østergaard L, Olesen JB, Petersen JK, et al. Arterial thromboembolism in patients with atrial fibrillation and CHA2DS2-VASc 1: a nationwide study. Circulation. 2024;149:764-773. 38152890.
Reversal of Intestinal Failure With Teduglutide in PERCC1-Associated Enteropathy: A Case Report [0.03%]
特杜谷肽治疗PERCC1相关肠病性肠功能障碍恢复的病例报告
Emily Stenke,Cara Dunne,Anthea Bryce-Smyth et al.
Emily Stenke et al.
In community-acquired pneumonia, adding oral clarithromycin to standard care increased early clinical response [0.03%]
在社区获得性肺炎中，常规治疗加口服克拉霉素可提高早期临床疗效
Henry S Sacks
Henry S Sacks
Giamarellos-Bourboulis EJ, Siampanos A, Bolanou A, et al. Clarithromycin for early anti-inflammatory responses in community-acquired pneumonia in Greece (ACCESS): a randomised, double-blind, placebo-controlled trial. Lancet Respir Med. 2024...
Randomized Controlled Trial
Annals of internal medicine. 2024 May;177(5):JC51. DOI:10.7326/J24-0022 2024
New use of thiazide diuretics vs. nonthiazide antihypertensive drugs was linked to hyponatremia over 2 y [0.03%]
与非噻嗪类降压药相比，新使用噻嗪类利尿剂两年内低钠血症的风险更高
Mansi Mehta,David S Goldfarb
Mansi Mehta
Andersson NW, Wohlfahrt J, Feenstra B, et al. Cumulative incidence of thiazide-induced hyponatremia: a population-based cohort study. Ann Intern Med. 2024;177:1-11. 38109740.