In adults with AMI who are at risk for HF, empagliflozin did not reduce a composite of first HF hospitalization or all-cause death at 18 mo [0.03%]
在因急性冠脉综合征住院的成人2型糖尿病患者中，达格列净未能降低心力衰竭或全因死亡复合终点的风险：DAPA-AMI试验
Stormy Keppel,Steven Borzak
Stormy Keppel
Butler J, Jones WS, Udell JA, et al. Empagliflozin after acute myocardial infarction. N Engl J Med. 2024;390:1455-1466. 38587237.
Randomized Controlled Trial
Annals of internal medicine. 2024 Jul;177(7):JC74. DOI:10.7326/ANNALS-24-00809-JC 2024
Medication-Induced Weight Change Across Common Antidepressant Treatments : A Target Trial Emulation Study [0.03%]
常见抗抑郁药物治疗的药物诱导体重变化：目标试验模拟研究
Joshua Petimar,Jessica G Young,Han Yu et al.
Joshua Petimar et al.
Background: Antidepressants are among the most commonly prescribed medications, but evidence on comparative weight change for specific first-line treatments is limited. ...
Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers for Advanced Chronic Kidney Disease : A Systematic Review and Retrospective Individual Participant-Level Meta-analysis of Clinical Trials [0.03%]
血管紧张素转换酶抑制剂或血管紧张素受体阻滞剂在慢性肾脏病进展中的应用：临床试验系统评价和个体患者数据荟萃分析
Elaine Ku,Lesley A Inker,Hocine Tighiouart et al.
Elaine Ku et al.
Background: In patients with advanced chronic kidney disease (CKD), the effects of initiating treatment with an angiotensin-converting enzyme inhibitor (ACEi) or angiotensin-receptor blocker (ARB) on the risk for kidney f...
Meta-Analysis
Annals of internal medicine. 2024 Jul;177(7):953-963. DOI:10.7326/M23-3236 2024
In device-detected AF, DOACs vs. aspirin or placebo reduce ischemic stroke and increase major bleeding [0.03%]
在设备检测到的心房颤动中，DOACs与阿司匹林或安慰剂相比，可减少缺血性卒中但增加大出血风险
Geoffrey D Barnes
Geoffrey D Barnes
McIntyre WF, Benz AP, Becher N, et al. Direct oral anticoagulants for stroke prevention in patients with device-detected atrial fibrillation: a study-level meta-analysis of the NOAH-AFNET 6 and ARTESiA trials. Circulation. 2024;149:981-988....
In patients with the kidney-dysfunction triad, facilitated evidence-based care did not reduce hospitalizations at 1 y [0.03%]
在肾脏功能异常三联征患者中，基于循证的护理并未减少1年内的住院率
Matthew T James,Kerry A McBrien
Matthew T James
Vazquez MA, Oliver G, Amarasingham R, et al; ICD-Pieces Study Group. Pragmatic trial of hospitalization rate in chronic kidney disease. N Engl J Med. 2024;390:1196-1206. 38598574.
mRNA COVID-19 vaccination during pregnancy was not linked to increased adverse neonatal outcomes [0.03%]
孕期接种新冠mRNA疫苗不会增加新生儿不良预后的风险
Robert P Kauffman
Robert P Kauffman
Norman M, Magnus MC, Söderling J, et al. Neonatal outcomes after COVID-19 vaccination in pregnancy. JAMA. 2024;331:396-407. 38319332.
Effect of Acupuncture on Neurogenic Claudication Among Patients With Degenerative Lumbar Spinal Stenosis : A Randomized Clinical Trial [0.03%]
针刺治疗退变性腰椎管狭窄症神经源性间歇性跛行的临床研究：一项随机对照试验
Lili Zhu,Yuanjie Sun,Jing Kang et al.
Lili Zhu et al.
Background: Acupuncture may improve degenerative lumbar spinal stenosis (DLSS), but evidence is insufficient. Objective: To investigate...
In adults with COVID-19 and severe hypoxemia, lower vs. higher oxygenation targets increased days alive without life support [0.03%]
在成人COVID-19严重低氧血症患者中，较低的氧气目标与较高的氧气目标相比可增加无生命支持天数
Daniel A Sweeney,Andre C Kalil
Daniel A Sweeney
Nielsen FM, Klitgaard TL, Siegemund M, et al; HOT-COVID Trial Group. Lower vs higher oxygenation target and days alive without life support in COVID-19: the HOT-COVID randomized clinical trial. JAMA. 2024;331:1185-1194. 38501214.
Randomized Controlled Trial
Annals of internal medicine. 2024 Jul;177(7):JC77. DOI:10.7326/ANNALS-24-00558-JC 2024