After endocrine therapy for postmenopausal early breast cancer, allocation to aromatase inhibitors reduced recurrence at 10 y [0.03%]
绝经后期乳腺癌内分泌治疗之后他莫昔芬换用芳香化酶抑制剂可降低十年间的复发风险
Nicholas Wilcken;ACP Journal Club Editorial Team at McMaster University
Nicholas Wilcken;ACP Journal Club Editorial Team at McMaster University
GIM/FP/GP: [Formula: see text].
In minor stroke, adding IV thrombolysis to nonthrombolytic usual care does not increase excellent functional outcome at 90 d [0.03%]
在小卒中患者中，在非溶栓常规治疗基础上加用静脉组织型纤溶酶原激活剂(thrombolysis with alteplase)注射并未提高90天时的良好功能预后率
Avi Singh Gandh,Mithilesh Siddu,Dinesh Jillella;ACP Journal Club Editorial Team at McMaster University
Avi Singh Gandh
Emergency Med: [Formula: see text] GIM/FP/GP: [Formula: see text] Neurology: [Formula: see text].
In adults with obesity but without type 2 diabetes, tirzepatide increased weight loss at 72 wk compared with semaglutide [0.03%]
在没有2型糖尿病的肥胖成人中， Tirzepatide的体重损失效果优于Semaglutide，持续长达72周
Lenard I Lesser;ACP Journal Club Editorial Team at McMaster University
Lenard I Lesser;ACP Journal Club Editorial Team at McMaster University
GIM/FP/GP: [Formula: see text] Endocrinology: [Formula: see text].
In older, frail, VKA-experienced patients with AF, SD-DOACs vs. warfarin reduced thrombotic events without increasing major bleeding [0.03%]
在老年虚弱的华法尼经验患者中，NOAC与华法林相比，在不增加大出血的情况下减少房颤患者的栓塞事件
Kouta Ito;ACP Journal Club Editorial Team at McMaster University
Kouta Ito;ACP Journal Club Editorial Team at McMaster University
GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text] Hematology: [Formula: see text].
Robert M Centor
Robert M Centor
In adults living near highways, 30 d of home HEPA vs. sham filtration did not differ for BP [0.03%]
与假过滤相比，成人在家使用HEPA过滤器30天对血压没有影响
Anthony A Donato,Iman Waheed Khan;ACP Journal Club Editorial Team at McMaster University
Anthony A Donato
GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text] Public Health: [Formula: see text].
Artificial Intelligence-Assisted Data Extraction With a Large Language Model: A Study Within Reviews [0.03%]
基于大规模语言模型的AI辅助数据提取研究：在评论中的应用
Gerald Gartlehner,Shannon Kugley,Karen Crotty et al.
Gerald Gartlehner et al.
Background: Data extraction is a critical but error-prone and labor-intensive task in evidence synthesis. Unlike other artificial intelligence (AI) technologies, large language models (LLMs) do not require labeled trainin...
Evidence for the efficacy of phosphate binders for preventing CKD complications was mostly low to very low certainty [0.03%]
磷酸盐结合剂预防CKD并发症有效性的证据 certainty较低至非常低
Kirsty Crowe,Patrick B Mark;ACP Journal Club Editorial Team at McMaster University
Kirsty Crowe
GIM/FP/GP: [Formula: see text] Nephrology: [Formula: see text].
Proteinuria or Albuminuria as Markers of Kidney and Cardiovascular Disease Risk : An Individual Patient-Level Meta-analysis [0.03%]
蛋白尿和白蛋白尿作为肾脏及心血管疾病风险标志的 meta 分析：基于个体患者数据的系统评价和meta分析
Hiddo J L Heerspink,Morgan E Grams,Yingying Sang et al.
Hiddo J L Heerspink et al.
Background: Urinary albumin-creatinine ratio (UACR) and urinary protein-creatinine ratio (UPCR) are both used in clinical practice to diagnose and monitor chronic kidney disease (CKD). Which measure exhibits stronger asso...
The Michigan Appropriateness Guide for Intravenous Catheters in Adult Patients With Cancer (MAGIC-ONC): Results From a Multispecialty Panel Using the RAND/UCLA Appropriateness Method [0.03%]
密歇根成人癌症患者静脉导管使用恰当性指南(MAGIC-ONC):采用RAND/UCLA恰当性方法的多学科专家组结果
Ajay Major,David G Paje,Knut Taxbro et al.
Ajay Major et al.
Safe and reliable venous access is critical for high-quality cancer care. Patients with both solid and hematologic cancers require vascular access devices (VADs) for systemic chemotherapies and for supportive treatments, including blood pro...