DLGAP5 Drives Lung Cancer Progression: Combined Bioinformatics and Clinical Prognostic Analysis [0.03%]
基于生物信息学和临床预后分析的DLGAP5促进肺癌进展
Min She,Chang Li,Fuxiang Li
Min She
DLGAP5 has emerged as a potential biomarker implicated in tumor progression across various cancers, yet its prognostic value in lung cancer remains to be fully elucidated. In this study, we integrated comprehensive bioinformatics analyses w...
Monocytes Provoke Breast Cancer Cells to Express PD-L1 via a Cell-to-Cell Interaction Involving CD44 and Moesin [0.03%]
单核细胞通过涉及CD44和Moesin的细胞相互作用促使乳腺癌细胞表达PD-L1
Saya Matsumoto,Tsunao Kishida,Shin-Ichiro Kotani et al.
Saya Matsumoto et al.
Triple-negative breast cancers (TNBCs), especially metastatic recurrent TNBCs, have a poorer prognosis than many other breast cancers. In recent years, immunotherapy using immune checkpoint inhibitors has been conducted for TNBC patients. A...
Design of Therapeutic Vaccines Based on Antigen Epitopes of α-9 HPV E6 in Sichuan [0.03%]
基于四川α-9型HPV E6抗原表位的治疗性疫苗设计
Jiaoyu He,Chunlan Cheng,Yishan Ding et al.
Jiaoyu He et al.
Persistent infections with high-risk human papillomavirus (HR-HPV) are the primary cause of vaginal/cervical squamous intraepithelial neoplasia (VAIN/CIN) and cervical cancer (CC), with the prevalence of infection escalating alongside disea...
Post-Translational Modification Mediated By Acylation Modification Related Genes Induces Immunosuppression and Immunotherapy Resistance in Head and Neck Squamous Cell Carcinoma [0.03%]
泛酰化修饰相关基因介导的翻译后修饰诱导头颈鳞癌免疫抑制和免疫治疗耐药性
Youwei Li,Xinqing Liu,Jinzhi Wu
Youwei Li
Acylation modification plays a crucial role in modulating head and neck squamous cell carcinoma (HNSCC) progression, and their specific prognostic implications in HNSCC have not been thoroughly investigated. Eleven acylation modifications (...
FGL1 as an Immune Checkpoint in the Immune Microenvironment of Bladder Cancer [0.03%]
FGL1在膀胱癌免疫微环境中的免疫检查点作用机制研究
Keyao Hu,Xiaocheng Ma,Lei Luo et al.
Keyao Hu et al.
Current treatment protocols for bladder cancer (BC) do not include additional immune checkpoint targets or biomarkers that can accurately predict treatment response. Hence, it is imperative to identify more inclusive and promising candidate...
Brief Communication: Severe Immuno-Induced Rhinosinusitis With Deafness After Ipilimumab and Nivolumab Combination for Melanoma, and Review of the Literature [0.03%]
伊匹单抗和纳武单抗联合治疗黑色素瘤后出现严重免疫相关性鼻窦炎并伴随听力下降的病例报告及文献复习
Maëva Boyer,Mélodie Kerimian,Alix Ribadeau Dumas et al.
Maëva Boyer et al.
Immunotherapy with immune checkpoint inhibitors (ICI) is widely used to treat cancers, and reports of rare immune-related adverse events (irAEs) are increasing. Ear, nose, and throat (ENT) irAEs are often underestimated, as patients rarely ...
Treatment With PD-1/PD-L1 Inhibitors for Kaposi Sarcoma: A Systematic Review and Meta-Analysis [0.03%]
PD-1/PD-L1抑制剂治疗卡波西肉瘤的系统评价和meta分析
Francisco Cezar Aquino de Moraes,Michele Kreuz,Pedro Henrique de Souza Wagner et al.
Francisco Cezar Aquino de Moraes et al.
Kaposi Sarcoma (KS) is an angioproliferative tumor induced by human gammaherpesvirus 8 (HHV-8). For years, cytotoxic chemotherapy was the primary treatment for advanced KS, despite high toxicity and limited efficacy. Immunotherapy, particul...
Prognostic Role of Early Dynamic Changes in Neutrophil-to-Lymphocyte Ratio of Nonsmall Cell Lung Cancer Patients [0.03%]
非小细胞肺癌患者中性粒细胞与淋巴细胞比率早期动态变化的预后价值
Xiaoyan Liu,Dongming Zhang,Haoran Zhang et al.
Xiaoyan Liu et al.
To explore the relationship between early dynamic changes in neutrophil-to-lymphocyte ratio (NLR) and lymphocyte-to-monocyte ratio (LMR) and treatment outcomes of patients with advanced nonsmall cell lung cancer (NSCLC) undergoing immunothe...
Identification of 2 Ubiquitin-Proteasome System-Related Subtypes in Esophageal Squamous Cell Carcinoma for Prognostic and Immunotherapeutic Response Prediction [0.03%]
鉴定食管鳞癌中的两个泛素-蛋白酶体系统相关亚型用于预后和免疫治疗反应预测
Chao Jiang,Meng Shen,Jing Zhu et al.
Chao Jiang et al.
Ubiquitin-proteasome system (UPS) is implicated in pathogenesis and progression of esophageal squamous cell carcinoma (ESCC), representing a promising therapeutic target. However, clinical significance of UPS in ESCC remains incompletely el...
Integrating Bulk RNA-Seq and Spatial Transcriptomics Data to Reveal Distinct Immune Escape Mechanism and Immunotherapy Based on Post-Translational Modification in Head and Neck Squamous Cell Carcinoma [0.03%]
结合批量RNA-seq和空间转录组数据揭示头颈鳞癌基于翻译后修饰的免疫逃逸机制及免疫治疗
Kai Li,Chuyi Cai,Qingmei Chen et al.
Kai Li et al.
Post-translational modification (PTM) plays a crucial role in head and neck squamous cell carcinoma (HNSCC) progression, and their specific prognostic implications in HNSCC have not been thoroughly investigated. TCGA-HNSCC, GSE41613, GSE427...