Malignant Transformation of a Pediatric Intracranial Nongerminomatous Germ Cell Tumor to Embryonal Rhabdomyosarcoma: Case Report and Literature Review [0.03%]
儿童颅内非生殖细胞瘤样germinocytoma恶变为胚胎性横纹肌肉瘤的病例报告及文献复习
Elizabeth S Borden,Ben Posorske,Clayton Long et al.
Elizabeth S Borden et al.
Malignant transformation of intracranial nongerminomatous germ cell tumors (NGGCTs) is a rare but clinically relevant phenomenon. We present the case of a 13-year-old boy with a localized, pineal NGGCT. After an initial favorable response, ...
Navigating Management of Spindle Cell/Sclerosing Rhabdomyosarcoma With FUS::TFCP2 Fusion in the Era of Targeted Therapy [0.03%]
靶向治疗时代脊索细胞/硬化性横纹肌肉瘤的诊断和治疗：带有FUS::TFCP2融合的病例报告及文献回顾
Olayinka Okeleji,Reeja Raj,Sherani Farha et al.
Olayinka Okeleji et al.
Spindle cell/sclerosing rhabdomyosarcoma (ssRMS) with FUS-TFCP2 translocation is a rare, aggressive RMS subtype often involving facial and pelvic bones and showing poor response to standard therapy. The FUS-TFCP2 fusion drives ALK gene acti...
Delayed Complementary Feeding as a Risk Factor for Vitamin K Deficiency Bleeding in a 9-Month-Old Infant [0.03%]
喂养延迟导致9月龄婴儿维生素K缺乏性出血的风险因素分析
Ponni G Jayan,Sheeja Sugunan,Devakumar V Krishnannair et al.
Ponni G Jayan et al.
Vitamin K deficiency bleeding (VKDB) is a well-known entity in the newborn period, classically presenting during the first week of life. VKDB causing massive bleeding beyond 3 months of age, in an otherwise healthy child, is extremely rare....
Increased Red Blood Cell Count With High Hemoglobin Indicates a Different Diagnosis From Beta-thalassemia Trait, Regardless of Mean Corpuscular Volume: Hereditary Hemochromatosis-A Retrospective Analysis [0.03%]
红细胞计数和血红蛋白水平升高提示与β-地中海贫血不同诊断：遗传性铁负荷过度症-回顾性分析
Deniz Aslan,Ali Kadir Koç,Ferda Emriye Perçin
Deniz Aslan
Hereditary hemochromatosis (HH) is an iron storage disorder characterized by increased iron absorption leading to elevated erythrocyte parameters, including red blood cell (RBC) count. It is the most common genetic disorder in Caucasians an...
Optimized Flow Cytometry Incorporating t-SNE Enables Minimal Residual Disease Assessment in a Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia at or Near the Lower Detection Limit [0.03%]
优化的流式细胞术结合t-SNE能够以最低检测限评估费城染色体阳性急性淋巴细胞白血病中的最小残余病灶
Kenichiro Kobayashi,Shumpei Mizuta,Yuka Ohashi et al.
Kenichiro Kobayashi et al.
Unsupervised machine learning shows significant promise for evaluating multicolor flow cytometry, particularly in advancing minimal residual disease (MRD) analysis. We implemented t-distributed stochastic neighbor embedding (t-SNE)-assisted...
Outcomes With Risk-Stratified Treatment Algorithm for Childhood ALL in India [0.03%]
印度儿童急性淋巴细胞白血病风险 stratified治疗方案的疗效
Maddukuri Sriram,Sneha Bhosle,Amita Mahajan
Maddukuri Sriram
Risk-stratified management with reduced-treatment intensity for standard-risk (SR) patients is an effective strategy. With treatment-related mortality (TRM) continuing to be a major concern in low-middle-income countries, it is vital to lim...
Experimental Treatment of Measles Encephalitis With Inosine Pranobex and Remdesivir in a Child With Lymphocytic Leukemia [0.03%]
利巴韦林和瑞德西韦治疗淋巴细胞白血病儿童麻疹脑炎的实验疗法
Rajani Cheriyan,Nanda Kumar,Kalasekhar Vijayasekharan et al.
Rajani Cheriyan et al.
Measles encephalitis results in devastating epilepsia partialis and/or mortality in the majority of children treated with intense chemotherapy for hematolymphoid malignancies. Although many agents have been studied in the treatment of Measl...
KMT2A::NRIP3 Fusion Gene in the First Reported Case of B-Cell Acute Lymphoblastic Leukemia [0.03%]
首个B细胞急性淋巴细胞白血病KT2A::NRIP3基因融合病例报告
Bingqing Huang,Yujiao Jia,Benquan Qi et al.
Bingqing Huang et al.
Background: The KMT2A rearrangements is primarily caused by balanced translocations, with only a very small fraction resulting from deletions or inversions within the long arm of chromosome 11. ...
Relapsed Pancreatoblastoma in Children: The Quest for Cure in This Rare Entity [0.03%]
儿童胰腺母细胞瘤复发：探寻这一罕见实体的治愈之路
Carlos Echecopar,Erika Pace,Maesha Deheragoda et al.
Carlos Echecopar et al.
Pancreatoblastoma constitutes the most common malignant pancreatic tumor in children. Pancreatoblastomas are rare and data to generate evidence-based management guidelines are limited. A literature review and pooled data analysis of cases 1...
Impact of Graft CD3 Lymphocyte Cell Dose on Clinical Outcome of Children Undergoing Haploidentical Peripheral Blood Stem Cell Transplantation With Post-transplantation Cyclophosphamide [0.03%]
移植物CD3淋巴细胞剂量对单倍型相合外周血造血干细胞移植后应用环磷酰胺儿童受者预后影响的研究
Upasana Karthik,Dhwanee Thakkar,Aseem K Tiwari et al.
Upasana Karthik et al.