Thomas Chartrand,Mark S Goldman,Timothy J Lewis
Thomas Chartrand
Electrical coupling between neurons is broadly present across brain areas and is typically assumed to synchronize network activity. However, intrinsic properties of the coupled cells can complicate this simple picture. Many cell types with ...
A REDUCTION METHOD FOR BOOLEAN NETWORK MODELS PROVEN TO CONSERVE ATTRACTORS [0.03%]
一种能保持稳态的布尔网络模型化简方法
Assieh Saadatpour,RÉka Albert,Timothy C Reluga
Assieh Saadatpour
Boolean models, wherein each component is characterized with a binary (ON or OFF) variable, have been widely employed for dynamic modeling of biological regulatory networks. However, the exponential dependencse of the size of the state spac...
Neurologically Motivated Coupling Functions in Models of Motor Coordination [0.03%]
神经学启发的运动协调模型耦合函数
Piotr Słowiński,Sohaib Al-Ramadhani,Krasimira Tsaneva-Atanasova
Piotr Słowiński
We present an analysis of two Haken-Kelso-Bunz (HKB) oscillators coupled by a neurologically motivated function. We study the effect of time delay and weighted self-feedback and mutual feedback on the synchronization behavior of the model. ...
Bree Cummins,Tomas Gedeon,Shaun Harker et al.
Bree Cummins et al.
We show how a graph algorithm for finding matching labeled paths in pairs of labeled directed graphs can be used to perform model invalidation for a class of dynamical systems including regulatory network models of relevance to systems biol...
Bree Cummins,Tomas Gedeon,Shaun Harker et al.
Bree Cummins et al.
We describe the theoretical and computational framework for the Dynamic Signatures for Genetic Regulatory Network ( DSGRN) database. The motivation stems from urgent need to understand the global dynamics of biologically relevant signal tra...
A GRAPH PARTITIONING APPROACH TO PREDICTING PATTERNS IN LATERAL INHIBITION SYSTEMS [0.03%]
图划分预测侧向抑制系统中的模式的一种方法
Ana S Rufino Ferreira,Murat Arcak
Ana S Rufino Ferreira
We analyze spatial patterns on networks of cells where adjacent cells inhibit each other through contact signaling. We represent the network as a graph where each vertex represents the dynamics of identical individual cells and where graph ...
Marcella M Gomez,Richard M Murray,Matthew R Bennett
Marcella M Gomez
Delays in gene networks result from the sequential nature of protein assembly. However, it is unclear how models of gene networks that use delays should be modified when considering time-dependent changes in temperature. This is important, ...
Understanding Policy Diffusion in the U.S.: An Information-Theoretical Approach to Unveil Connectivity Structures in Slowly Evolving Complex Systems [0.03%]
理解美国政策扩散的信息理论方法：揭开缓慢进化复杂系统中的连通性结构
Ross P Anderson,Geronimo Jimenez,Jin Yung Bae et al.
Ross P Anderson et al.
Detecting and explaining the relationships among interacting components has long been a focal point of dynamical systems research. In this paper, we extend these types of data-driven analyses to the realm of public policy, whereby individua...
Stability of Systems with Stochastic Delays and Applications to Genetic Regulatory Networks [0.03%]
具随机时滞系统的稳定性及其在基因调控网络中的应用
Marcella M Gomez,Mehdi Sadeghpour,Matthew R Bennett et al.
Marcella M Gomez et al.
The dynamics of systems with stochastically varying time delays are investigated in this paper. It is shown that the mean dynamics can be used to derive necessary conditions for the stability of equilibria of the stochastic system. Moreover...
Calcium and Metabolic Oscillations in Pancreatic Islets: Who's Driving the Bus?* [0.03%]
钙与胰岛代谢振荡：谁在驾驶这辆巴士？
Margaret Watts,Bernard Fendler,Matthew J Merrins et al.
Margaret Watts et al.
Pancreatic islets exhibit bursting oscillations in response to elevated blood glucose. These oscillations are accompanied by oscillations in the free cytosolic Ca2+ concentration (Cac ), which drives pulses of insulin secretion. Both islet ...