Peroxisomal peripheral membrane protein YlInp1p is required for peroxisome inheritance and influences the dimorphic transition in the yeast Yarrowia lipolytica [0.03%]
过氧化物酶体周质膜蛋白YlInp1p对过氧化物酶体遗传和脂酵母毕赤氏亚裂殖酵母形态转换的影响作用
Jinlan Chang,Andrei Fagarasanu,Richard A Rachubinski
Jinlan Chang
Eukaryotic cells have evolved molecular mechanisms to ensure the faithful inheritance of organelles by daughter cells in order to maintain the benefits afforded by the compartmentalization of biochemical functions. Little is known about the...
Choline induces transcriptional repression and proteasomal degradation of the malarial phosphoethanolamine methyltransferase [0.03%]
胆碱通过转录抑制和蛋白酶体降解诱导疟疾磷乙醇胺甲基转移酶
William Harold Witola,Choukri Ben Mamoun
William Harold Witola
During its intraerythrocytic life cycle, the malaria parasite Plasmodium falciparum undergoes dramatic metabolic and morphological changes and multiplies to produce up to 36 new daughter parasites. This rapid multiplication of the parasite ...
Jaap J van Hellemond,Aad Hoek,Paul Wichgers Schreur et al.
Jaap J van Hellemond et al.
Bloodstream form Trypanosoma theileri degrades glucose to acetate (47%) and succinate (45%) and, therefore, does not solely rely on glycolysis for ATP production. This trypanosomatid does not use amino acids for energy metabolism. These res...
Role of laeA in the Regulation of alb1, gliP, Conidial Morphology, and Virulence in Aspergillus fumigatus [0.03%]
LaeA在烟曲霉alb1、gliP表达、分生孢子形态和致病性调控中的作用
Janyce A Sugui,Julian Pardo,Yun C Chang et al.
Janyce A Sugui et al.
The alb1 (pksP) gene has been reported as a virulence factor controlling the pigmentation and morphology of conidia in Aspergillus fumigatus. A recent report suggested that laeA regulates alb1 expression and conidial morphology but not pigm...
Response regulators SrrA and SskA are central components of a phosphorelay system involved in stress signal transduction and asexual sporulation in Aspergillus nidulans [0.03%]
响应调节因子SrrA和SskA是参与烟曲霉胁迫信号转导和无性孢子形成的磷酸传递系统的核心组成部分
Itzel Vargas-Pérez,Olivia Sánchez,Laura Kawasaki et al.
Itzel Vargas-Pérez et al.
Among eukaryotes, only slime molds, fungi, and plants contain signal transduction phosphorelay systems. In filamentous fungi, multiple sensor kinases appear to use a single histidine-containing phosphotransfer (HPt) protein to relay signals...
Aspergillus nidulans conidiation genes dewA, fluG, and stuA are differentially regulated in early vegetative growth [0.03%]
曲霉属nidulans生长期的营养体生长早期阶段分化基因dewA、fluG和stuA的差异调控
Andrew Breakspear,Michelle Momany
Andrew Breakspear
Microarray analysis was used to identify transcriptional changes in early vegetative growth of the filamentous fungus Aspergillus nidulans. The results suggest that the previously identified conidiation genes dewA, fluG, and stuA may functi...
EhLimA, a novel LIM protein, localizes to the plasma membrane in Entamoeba histolytica [0.03%]
新型的LIM蛋白EhLimA定位于溶组织内阿米巴的胞浆膜上
Nomy Wender,Eduardo Villalobo,David Mirelman
Nomy Wender
The parasitic protozoan Entamoeba histolytica relies on a very dynamic cytoskeleton in order to invade and survive in host tissues. Identification of cytoskeletal elements is key to understanding these processes. Here we present the charact...
Flip-flop of fluorescently labeled phospholipids in proteoliposomes reconstituted with Saccharomyces cerevisiae microsomal proteins [0.03%]
荧光标记的磷脂在酿酒酵母微胞浆蛋白组成的蛋白脂质体中的翻转流动
Stefanie Vehring,Leroy Pakkiri,Adrien Schröer et al.
Stefanie Vehring et al.
A phospholipid flippase activity from the endoplasmic reticulum (ER) of the model organism Saccharomyces cerevisiae has been characterized and functionally reconstituted into proteoliposomes. Analysis of the transbilayer movement of acyl-7-...
The high-osmolarity glycerol response pathway in the human fungal pathogen Candida glabrata strain ATCC 2001 lacks a signaling branch that operates in baker's yeast [0.03%]
模式酵母菌株中高渗甘油反应通路缺乏作用于人形隐球病原菌中的信号分支
Christa Gregori,Christoph Schüller,Andreas Roetzer et al.
Christa Gregori et al.
The high-osmolarity glycerol (HOG) mitogen-activated protein (MAP) kinase pathway mediates adaptation to high-osmolarity stress in the yeast Saccharomyces cerevisiae. Here we investigate the function of HOG in the human opportunistic fungal...
Histone deacetylase activity regulates chemical diversity in Aspergillus [0.03%]
组蛋白脱乙酰酶活性调控曲霉属次级代谢化学多样性
E Keats Shwab,Jin Woo Bok,Martin Tribus et al.
E Keats Shwab et al.
Bioactive small molecules are critical in Aspergillus species during their development and interaction with other organisms. Genes dedicated to their production are encoded in clusters that can be located throughout the genome. We show that...