Ku heterodimer-independent end joining in Trypanosoma brucei cell extracts relies upon sequence microhomology [0.03%]
序列微同源依赖的克鲁皮细胞裂解液中的 Ku 二聚体非依赖性末端连接反应
Peter Burton,David J McBride,Jonathan M Wilkes et al.
Peter Burton et al.
DNA double-strand breaks (DSBs) are repaired primarily by two distinct pathways: homologous recombination and nonhomologous end joining (NHEJ). NHEJ has been found in all eukaryotes examined to date and has been described recently for some ...
An Sfi1p-like centrin-binding protein mediates centrin-based Ca2+ -dependent contractility in Paramecium tetraurelia [0.03%]
一个类似SFI1P的中心粒结合蛋白介导了草履虫中的基于中心粒的钙离子依赖性收缩作用
Delphine Gogendeau,Janine Beisson,Nicole Garreau de Loubresse et al.
Delphine Gogendeau et al.
The previous characterization and structural analyses of Sfi1p, a Saccharomyces cerevisiae centrin-binding protein essential for spindle pole body duplication, have suggested molecular models to account for centrin-mediated, Ca2+-dependent ...
Colin P C De Souza,Stephen A Osmani
Colin P C De Souza
A cell number-counting factor regulates levels of a novel protein, SslA, as part of a group size regulation mechanism in Dictyostelium [0.03%]
一种细胞计数因子通过调节新型蛋白质SslA的水平来调控群体大小
Tong Gao,Celine Roisin-Bouffay,R Diane Hatton et al.
Tong Gao et al.
Developing Dictyostelium cells form aggregation streams that break into groups of approximately 2 x 10(4) cells. The breakup and subsequent group size are regulated by a secreted multisubunit counting factor (CF). To elucidate how CF regula...
Differential involvement of histidine kinase receptors in pseudohyphal development, stress adaptation, and drug sensitivity of the opportunistic yeast Candida lusitaniae [0.03%]
组氨酸受体在机会性酵母克鲁斯锥虫假菌丝发育、压力适应和药物敏感性中的不同作用
Florence Chapeland-Leclerc,Paméla Paccallet,Gwenaël Ruprich-Robert et al.
Florence Chapeland-Leclerc et al.
Fungal histidine kinase receptors (HKRs) sense and transduce many extracellular signals. We investigated the role of HKRs in morphogenetic transition, osmotolerance, oxidative stress response, and mating ability in the opportunistic yeast C...
A Toxoplasma gondii leucine-rich repeat protein binds phosphatase type 1 protein and negatively regulates its activity [0.03%]
一种弓形虫含亮氨酸丰富的重复蛋白结合到磷酸酶1蛋白上并对其活性具有抑制作用
Wassim Daher,Gabrielle Oria,Sylvain Fauquenoy et al.
Wassim Daher et al.
We have characterized the Toxoplasma gondii protein phosphatase type 1 (TgPP1) and a potential regulatory binding protein belonging to the leucine-rich repeat protein family, designated TgLRR1. TgLRR1 is capable of binding to TgPP1 to inhib...
FEA1, FEA2, and FRE1, encoding two homologous secreted proteins and a candidate ferrireductase, are expressed coordinately with FOX1 and FTR1 in iron-deficient Chlamydomonas reinhardtii [0.03%]
铁缺乏情况下，编码两个同源分泌蛋白和一个候选铁还原酶的FEA1、FEA2 和FRE1 基因与FOX1 和FTR1 协调表达
Michael D Allen,José A del Campo,Janette Kropat et al.
Michael D Allen et al.
Previously, we had identified FOX1 and FTR1 as iron deficiency-inducible components of a high-affinity copper-dependent iron uptake pathway in Chlamydomonas. In this work, we survey the version 3.0 draft genome to identify a ferrireductase,...
Spitzenkorper localization and intracellular traffic of green fluorescent protein-labeled CHS-3 and CHS-6 chitin synthases in living hyphae of Neurospora crassa [0.03%]
带有绿色荧光蛋白标签的粗糙脉孢菌CHS-3和CHS-6几丁质合成酶的尖端体定位及其在活菌丝细胞内的运输路径
Meritxell Riquelme,Salomon Bartnicki-García,Juan Manuel González-Prieto et al.
Meritxell Riquelme et al.
The subcellular location and traffic of two selected chitin synthases (CHS) from Neurospora crassa, CHS-3 and CHS-6, labeled with green fluorescent protein (GFP), were studied by high-resolution confocal laser scanning microscopy. While we ...
Serum lipoproteins promote efficient presentation of the malaria virulence protein PfEMP1 at the erythrocyte surface [0.03%]
血清脂蛋白促进疟疾病原蛋白PfEMP1在红细胞表面有效呈递
Sarah Frankland,Salenna R Elliott,Francisca Yosaatmadja et al.
Sarah Frankland et al.
The virulence of the malaria parasite Plasmodium falciparum is related to its ability to express a family of adhesive proteins known as P. falciparum erythrocyte membrane protein 1 (PfEMP1) at the infected red blood cell surface. The mechan...
Antigenic variation in Plasmodium falciparum: gene organization and regulation of the var multigene family [0.03%]
恶性疟原虫表型变异的基因组织和调控
Sue A Kyes,Susan M Kraemer,Joseph D Smith
Sue A Kyes