A new, expressed multigene family containing a hot spot for insertion of retroelements is associated with polymorphic subtelomeric regions of Trypanosoma brucei [0.03%]
含有一个易被转座子插入热点的新表达的多基因家族与克氏锥虫多态亚端粒区域相关联
Frederic Bringaud,Nicolas Biteau,Sara E Melville et al.
Frederic Bringaud et al.
We describe a novel gene family that forms clusters in subtelomeric regions of Trypanosoma brucei chromosomes and partially accounts for the observed clustering of retrotransposons. The ingi and ribosomal inserted mobile element (RIME) non-...
CulB, a putative ubiquitin ligase subunit, regulates prestalk cell differentiation and morphogenesis in Dictyostelium spp [0.03%]
Dictyostelium 类鞭毛菌中 CulB（一种推定的泛素连接酶亚基）调控前茎细胞分化及形态建成
Bin Wang,Adam Kuspa
Bin Wang
Dictyostelium amoebae accomplish a starvation-induced developmental process by aggregating into a mound and forming a single fruiting body with terminally differentiated spores and stalk cells. culB was identified as the gene disrupted in a...
Calcium binding is required for calmodulin function in Aspergillus nidulans [0.03%]
钙结合是烟曲霉中钙调蛋白功能所必需的
James D Joseph,Anthony R Means
James D Joseph
To explore the structural basis for the essential role of calmodulin (CaM) in Aspergillus nidulans, we have compared the biochemical and in vivo properties of A. nidulans CaM (AnCaM) with those of heterologous CaMs. Neither Saccharomyces ce...
Comparative Study
Eukaryotic cell. 2002 Feb;1(1):119-25. DOI:10.1128/EC.01.1.119-125.2002 2002
Role of uridylate-specific exoribonuclease activity in Trypanosoma brucei RNA editing [0.03%]
尿苷特异的外核糖核酸酶在布氏冈比亚锥虫RNA编辑中的作用
Robert P Igo Jr,David S Weston,Nancy Lewis Ernst et al.
Robert P Igo Jr et al.
Editing of mitochondrial mRNAs in kinetoplastid protozoa occurs by a series of enzymatic steps that insert and delete uridylates (U's) as specified by guide RNAs (gRNAs). The characteristics of the 3' exonuclease activity that removes the U...
Pumilio homologue from saprolegnia parasitica specifically expressed in undifferentiated spore cysts [0.03%]
来自于Saprolegeina parasitica的Pumilio同源蛋白在未分化的孢子包中特异表达
M Gunnar Andersson,Lage Cerenius
M Gunnar Andersson
The expression of spore-specific marker transcripts at different stages of the asexual life cycle of Saprolegnia parasitica was analyzed. One of the markers, designated puf1, was found to be expressed transiently upon each of several cycles...
CDC42 is required for polarized growth in human pathogen Candida albicans [0.03%]
cdc42在致病性真菌白念珠菌极化生长中的作用研究
Sophia C Ushinsky,Doreen Harcus,Josee Ash et al.
Sophia C Ushinsky et al.
Cdc42p is a member of the RAS superfamily of GTPases and plays an essential role in polarized growth in many eukaryotic cells. We cloned the Candida albicans CaCDC42 by functional complementation in Saccharomyces cerevisiae and analyzed its...
Isolation and characterization of two ammonium permease genes, meaA and mepA, from Aspergillus nidulans [0.03%]
烟曲霉铵转运蛋白基因meaA和mepA的分离与鉴定
Brendon J Monahan,James A Fraser,Michael J Hynes et al.
Brendon J Monahan et al.
Ammonium and the analogue methylammonium are taken into the cell by active transport systems which constitute a family of transmembrane proteins that have been identified in fungi, bacteria, plants, and animals. Two genes from Aspergillus n...
Adenylyl cyclase functions downstream of the Galpha protein Gpa1 and controls mating and pathogenicity of Cryptococcus neoformans [0.03%]
腺苷酸环化酶位于G蛋白Gpa1的下游，调控新生隐球菌的交配和致病性
J Andrew Alspaugh,Read Pukkila-Worley,Toshiaki Harashima et al.
J Andrew Alspaugh et al.
The signaling molecule cyclic AMP (cAMP) is a ubiquitous second messenger that enables cells to detect and respond to extracellular signals. cAMP is generated by the enzyme adenylyl cyclase, which is activated or inhibited by the Galpha sub...
Saccharomyces cerevisiae C-type cyclin Ume3p/Srb11p is required for efficient induction and execution of meiotic development [0.03%]
酿酒酵母C型周期蛋白Ume3p/Srb11p对有丝分裂诱导和执行是必要的
Katrina F Cooper,Randy Strich
Katrina F Cooper
The yeast C-type cyclin Ume3p/Srb11p and its cyclin-dependent kinase partner Ume5p/Srb10p repress the transcription of several genes required for meiotic recombination or meiosis I nuclear division. To relieve this repression, Srbllp is des...
Yeast Rpi1 is a putative transcriptional regulator that contributes to preparation for stationary phase [0.03%]
酿酒酵母RPI1是一个假定的转录调节因子，在促进细胞进入停滞期方面发挥重要作用
Andrew K Sobering,Un Sung Jung,Kyung S Lee et al.
Andrew K Sobering et al.
The RPI1 gene of Saccharomyces cerevisiae was identified initially as a dosage suppressor of the heat shock sensitivity associated with overexpression of RAS2 (J. Kim and S. Powers, Mol. Cell. Biol. 11:3894-3904, 1991). Based on its failure...